MIR4263 Gene (RNA Gene)

MicroRNA 4263

GC02P027996
GIFtS:
12
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4263 Gene

Subcategory (RNA class) for MIR4263 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR4263 Gene

  • MicroRNA 4263 2 3 5
  • Hsa-Mir-4263 3
  • MIMAT0016898 53
  • MI0015876 53
  • MIR4263 2

External Ids for MIR4263 Gene

Previous GeneCards Identifiers for MIR4263 Gene

  • GC02U902061
  • GC02P028219

Summaries for MIR4263 Gene

Entrez Gene Summary for MIR4263 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4263 Gene

MIR4263 (MicroRNA 4263) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4263 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4263 Gene

Genomics for MIR4263 Gene

GeneHancer (GH) Regulatory Elements for MIR4263 Gene

Promoters and enhancers for MIR4263 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH02J027992 Enhancer 0.8 Ensembl ENCODE 0.6 -2.4 -2366 5.6 ZNF652 FOSL2 CREB1 POLR2A CEBPB ATF7 JUN JUND SP1 EP300 FNDC4 TRIM54 MIR4263 lnc-RBKS-5 BABAM2
GH02J028011 Enhancer 0.8 Ensembl 0.4 +15.0 15034 0.8 RBPJ NR2F1 MIXL1 HLF ELF3 TFE3 CEBPG PPARG ZNF644 KAT8 ENSG00000270528 LOC100505694 MIR4263 BABAM2
GH02J028003 Enhancer 0.6 Ensembl ENCODE 0.4 +7.8 7834 1.6 MAFK RUNX3 FOS JUND MIR4263 ENSG00000270528 LOC100505694 BABAM2
GH02J027988 Enhancer 0.5 ENCODE 0.4 -6.9 -6931 2.3 ZNF316 NFE2 MAFG CEBPG ZNF398 ZFP37 FNDC4 ENSG00000234072 lnc-RBKS-5 MIR4263 BABAM2
GH02J028009 Enhancer 0.2 Ensembl 0.4 +13.4 13434 0.4 ENSG00000270528 LOC100505694 MIR4263 BABAM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4263 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4263 Gene

Genomic Locations for MIR4263 Gene
chr2:27,996,367-27,996,449
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr2:28,219,234-28,219,316
(GRCh37/hg19)
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR4263 Gene

Genes around MIR4263 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4263 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4263 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4263 Gene

Proteins for MIR4263 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4263 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4263 Gene

Domains & Families for MIR4263 Gene

Gene Families for MIR4263 Gene

HGNC:
genes like me logo Genes that share domains with MIR4263: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4263 Gene

Function for MIR4263 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for MIR4263 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4263 Gene

Localization for MIR4263 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4263 Gene

Pathways & Interactions for MIR4263 Gene

PathCards logo

SuperPathways for MIR4263 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4263 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4263 Gene

Drugs & Compounds for MIR4263 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4263 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4263 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4263 Gene

No ASD Table

Relevant External Links for MIR4263 Gene

GeneLoc Exon Structure for
MIR4263
ECgene alternative splicing isoforms for
MIR4263

Expression for MIR4263 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4263 Gene

mRNA expression in normal human tissues for MIR4263 Gene
mRNA expression by GTEx for MIR4263 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4263 Gene:

MIR4263
genes like me logo Genes that share expression patterns with MIR4263: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4263 Gene

Orthologs for MIR4263 Gene

Evolution for MIR4263 Gene

ENSEMBL:
Gene Tree for MIR4263 (if available)
TreeFam:
Gene Tree for MIR4263 (if available)

No data available for Orthologs for MIR4263 Gene

Paralogs for MIR4263 Gene

No data available for Paralogs for MIR4263 Gene

Variants for MIR4263 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for MIR4263 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1003866015 -- 27,994,374(+) T/C upstream_transcript_variant
rs1004001658 -- 27,994,646(+) C/T upstream_transcript_variant
rs1004009481 -- 27,995,228(+) G/A upstream_transcript_variant
rs1006360299 -- 27,995,983(+) A/G upstream_transcript_variant
rs1007455774 -- 27,994,979(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4263 Gene

Variant ID Type Subtype PubMed ID
esv2759034 CNV gain 17122850

Additional Variant Information for MIR4263 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4263

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4263 Gene

Disorders for MIR4263 Gene

Additional Disease Information for MIR4263

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4263 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4263 Gene

Publications for MIR4263 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

ExternalLinks

View latest publications for MIR4263 gene in Mastermind

Products for MIR4263 Gene

Sources for MIR4263 Gene