Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4256 Gene

Subcategory (RNA class) for MIR4256 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4256 Gene

  • MicroRNA 4256 2 3 5
  • Hsa-Mir-4256 3

External Ids for MIR4256 Gene

Previous GeneCards Identifiers for MIR4256 Gene

  • GC01U902967
  • GC01M113004

Summaries for MIR4256 Gene

Entrez Gene Summary for MIR4256 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4256 Gene

MIR4256 (MicroRNA 4256) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4256 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4256 Gene

Genomics for MIR4256 Gene

GeneHancer (GH) Regulatory Elements for MIR4256 Gene

Promoters and enhancers for MIR4256 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I112461 Enhancer 0.5 ENCODE 550.8 +0.1 139 0.2 ATF1 TEAD4 CBFA2T3 ZNF24 KDM1A KDM4B MIR4256 CTTNBP2NL GC01P112397
GH01I112463 Enhancer 0.4 ENCODE 550.8 +0.5 519 0.2 SMARCE1 GATA3 MIR4256 CTTNBP2NL GC01P112397
GH01I112462 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.8 -2.9 -2934 5 HDGF PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B WNT2B LOC100421402 DDX20 ST7L LRIG2 CTTNBP2NL MIR4256
GH01I112402 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.2 +58.1 58075 4.3 ATF1 ZNF529 ZSCAN4 INSM2 KLF17 ZNF2 BRCA1 RFX5 ZEB1 ZNF366 WNT2B ENSG00000238761 ENSG00000260948 LOC100996251 PPM1J RHOC CTTNBP2NL MOV10 ENSG00000225075 GC01P112397
GH01I112456 Enhancer 0.3 ENCODE 0.8 +4.6 4642 2.1 FOS CTTNBP2NL WNT2B ENSG00000238761 MIR4256 GC01P112397
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4256 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4256 Gene

Genomic Locations for MIR4256 Gene
chr1:112,461,770-112,461,833
(GRCh38/hg38)
Size:
64 bases
Orientation:
Minus strand
chr1:113,004,392-113,004,455
(GRCh37/hg19)

Genomic View for MIR4256 Gene

Genes around MIR4256 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4256 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4256 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4256 Gene

ORGUL Member Location for MIR4256 Gene

ORGUL Member Location for MIR4256 gene

Proteins for MIR4256 Gene

Post-translational modifications for MIR4256 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4256 Gene

Domains & Families for MIR4256 Gene

Gene Families for MIR4256 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4256: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4256 Gene

Function for MIR4256 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4256 Gene

Localization for MIR4256 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4256 Gene

Pathways & Interactions for MIR4256 Gene

SuperPathways for MIR4256 Gene

No Data Available

Interacting Proteins for MIR4256 Gene

Gene Ontology (GO) - Biological Process for MIR4256 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4256 Gene

Drugs & Compounds for MIR4256 Gene

No Compound Related Data Available

Transcripts for MIR4256 Gene

mRNA/cDNA for MIR4256 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4256 Gene

No ASD Table

Relevant External Links for MIR4256 Gene

GeneLoc Exon Structure for
MIR4256
ECgene alternative splicing isoforms for
MIR4256

Expression for MIR4256 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4256 Gene:

MIR4256
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4256 Gene

Orthologs for MIR4256 Gene

Evolution for MIR4256 Gene

ENSEMBL:
Gene Tree for MIR4256 (if available)
TreeFam:
Gene Tree for MIR4256 (if available)

No data available for Orthologs for MIR4256 Gene

Paralogs for MIR4256 Gene

No data available for Paralogs for MIR4256 Gene

Variants for MIR4256 Gene

Sequence variations from dbSNP and Humsavar for MIR4256 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000977929 -- 112,463,076(-) C/T upstream_transcript_variant
rs1001413153 -- 112,462,465(-) T/C upstream_transcript_variant
rs1003618181 -- 112,463,457(-) G/T upstream_transcript_variant
rs1004524057 -- 112,463,407(-) T/C upstream_transcript_variant
rs1004914004 -- 112,461,903(-) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4256 Gene

Variant ID Type Subtype PubMed ID
esv27061 CNV gain+loss 19812545
nsv506955 OTHER sequence alteration 20534489
nsv831081 CNV loss 17160897

Additional Variant Information for MIR4256 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4256

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4256 Gene

Disorders for MIR4256 Gene

Additional Disease Information for MIR4256

No disorders were found for MIR4256 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4256 Gene

Publications for MIR4256 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4256 Gene

Sources for MIR4256 Gene

Content
Loading form....