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Aliases for MIR4254 Gene

Subcategory (RNA class) for MIR4254 Gene


Quality Score for this RNA gene is


Aliases for MIR4254 Gene

  • MicroRNA 4254 2 3 5
  • Hsa-Mir-4254 3

External Ids for MIR4254 Gene

Previous GeneCards Identifiers for MIR4254 Gene

  • GC01U903038
  • GC01M032224

Summaries for MIR4254 Gene

Entrez Gene Summary for MIR4254 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4254 Gene

MIR4254 (MicroRNA 4254) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4254 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4254 Gene

Genomics for MIR4254 Gene

GeneHancer (GH) Regulatory Elements for MIR4254 Gene

Promoters and enhancers for MIR4254 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I031759 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 550.8 -2.0 -1997 2.4 PKNOX1 ARID4B SIN3A BMI1 GLIS2 EGR1 ZNF366 ZSCAN5C ZNF143 FOS MIR4254 COL16A1 ENSG00000235790 LOC105378626 TINAGL1 ADGRB2
GH01I031756 Enhancer 0.6 dbSUPER 550.8 +1.0 1023 1.8 SMARCA5 BCOR ZMYM3 ZBTB7A POLR2A HDAC2 ADNP GLIS1 ZNF444 KDM1A MIR4254 COL16A1 ENSG00000235790 LOC105378626 TINAGL1 ADGRB2 GC01P031741
GH01I031762 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 0.8 -4.1 -4126 0.3 RB1 ARNT ZNF76 SIN3A ZNF48 RAD21 ZNF335 GLIS2 ZNF366 ZNF143 ADGRB2 MIR4254
GH01I031752 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.8 +4.3 4273 3.4 ZIC2 HIC1 CTBP1 ZNF316 ZBTB48 RCOR1 MAFK RXRA NFIA MAFG ADGRB2 MIR4254 GC01P031741
GH01I031763 Promoter/Enhancer 1.8 EPDnew Ensembl dbSUPER 0.4 -5.3 -5266 1.2 HDGF RB1 ZNF2 ZNF335 GLIS2 ZNF366 EGR2 ZNF398 REST ZEB2 ADGRB2 CCDC28B MIR4254
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4254 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4254 Gene

Genomic Locations for MIR4254 Gene
76 bases
Minus strand

Genomic View for MIR4254 Gene

Genes around MIR4254 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4254 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4254 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4254 Gene

ORGUL Member Location for MIR4254 Gene

ORGUL Member Location for MIR4254 gene

Proteins for MIR4254 Gene

Post-translational modifications for MIR4254 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4254 Gene

Domains & Families for MIR4254 Gene

Gene Families for MIR4254 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4254: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4254 Gene

Function for MIR4254 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4254 Gene

Localization for MIR4254 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4254 Gene

Pathways & Interactions for MIR4254 Gene

SuperPathways for MIR4254 Gene

No Data Available

Interacting Proteins for MIR4254 Gene

Gene Ontology (GO) - Biological Process for MIR4254 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4254 Gene

Drugs & Compounds for MIR4254 Gene

No Compound Related Data Available

Transcripts for MIR4254 Gene

mRNA/cDNA for MIR4254 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4254 Gene

No ASD Table

Relevant External Links for MIR4254 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4254 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4254 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4254 Gene:

genes like me logo Genes that share expression patterns with MIR4254: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4254 Gene

Orthologs for MIR4254 Gene

Evolution for MIR4254 Gene

Gene Tree for MIR4254 (if available)
Gene Tree for MIR4254 (if available)

No data available for Orthologs for MIR4254 Gene

Paralogs for MIR4254 Gene

No data available for Paralogs for MIR4254 Gene

Variants for MIR4254 Gene

Sequence variations from dbSNP and Humsavar for MIR4254 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002656717 -- 31,759,221(-) T/C upstream_transcript_variant
rs1003709127 -- 31,759,143(-) G/T upstream_transcript_variant
rs1004049146 -- 31,760,706(-) G/A upstream_transcript_variant
rs1004049530 -- 31,760,509(-) G/A upstream_transcript_variant
rs1006558354 -- 31,758,632(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4254 Gene

Variant ID Type Subtype PubMed ID
esv2758930 CNV loss 17122850
nsv1007390 CNV gain 25217958
nsv1007786 CNV gain 25217958
nsv950385 CNV deletion 24416366

Additional Variant Information for MIR4254 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4254 Gene

Disorders for MIR4254 Gene

Additional Disease Information for MIR4254

No disorders were found for MIR4254 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4254 Gene

Publications for MIR4254 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4254 Gene

Sources for MIR4254 Gene

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