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Aliases for MIR4251 Gene

Subcategory (RNA class) for MIR4251 Gene


Quality Score for this RNA gene is


Aliases for MIR4251 Gene

  • MicroRNA 4251 2 3 5
  • Hsa-Mir-4251 3

External Ids for MIR4251 Gene

Previous GeneCards Identifiers for MIR4251 Gene

  • GC01U903019
  • GC01P003044

Summaries for MIR4251 Gene

Entrez Gene Summary for MIR4251 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4251 Gene

MIR4251 (MicroRNA 4251) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4251 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4251 Gene

Genomics for MIR4251 Gene

GeneHancer (GH) Regulatory Elements for MIR4251 Gene

Promoters and enhancers for MIR4251 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I003127 Enhancer 0.6 dbSUPER 550.8 +0.6 625 2.2 ZSCAN4 MNT GLI4 ZNF148 GATA3 ZFHX2 EGR1 EGR2 MIR4251 ENSG00000226286 PRDM16
GH01I003125 Enhancer 0.5 ENCODE dbSUPER 0.8 -2.1 -2060 1.8 HLF MIR4251 PIR58969 PRDM16
GH01I003124 Enhancer 0.4 dbSUPER 0.8 -3.8 -3772 0.3 HNF4A NR2F2 MIR4251 PIR58969 PRDM16
GH01I003129 Enhancer 0.4 dbSUPER 0.8 +2.0 2011 0.4 GLIS2 ZIC2 MIR4251 ENSG00000226286 PRDM16
GH01I003126 Enhancer 0.4 dbSUPER 0.8 -3.3 -3311 0.7 HNF4A NR2F2 MIR4251 PIR58969 PRDM16
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4251 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4251 Gene

Genomic Locations for MIR4251 Gene
61 bases
Plus strand

Genomic View for MIR4251 Gene

Genes around MIR4251 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4251 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4251 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4251 Gene

Proteins for MIR4251 Gene

Post-translational modifications for MIR4251 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4251 Gene

Domains & Families for MIR4251 Gene

Gene Families for MIR4251 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4251: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4251 Gene

Function for MIR4251 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4251 Gene

Localization for MIR4251 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4251 Gene

Pathways & Interactions for MIR4251 Gene

SuperPathways for MIR4251 Gene

No Data Available

Interacting Proteins for MIR4251 Gene

Gene Ontology (GO) - Biological Process for MIR4251 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4251 Gene

Drugs & Compounds for MIR4251 Gene

No Compound Related Data Available

Transcripts for MIR4251 Gene

mRNA/cDNA for MIR4251 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4251 Gene

No ASD Table

Relevant External Links for MIR4251 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4251 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4251 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4251 Gene

Orthologs for MIR4251 Gene

Evolution for MIR4251 Gene

Gene Tree for MIR4251 (if available)
Gene Tree for MIR4251 (if available)

No data available for Orthologs for MIR4251 Gene

Paralogs for MIR4251 Gene

No data available for Paralogs for MIR4251 Gene

Variants for MIR4251 Gene

Sequence variations from dbSNP and Humsavar for MIR4251 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002101419 -- 3,127,246(+) A/G upstream_transcript_variant
rs1002154100 -- 3,127,330(+) C/G upstream_transcript_variant
rs1002322904 -- 3,128,068(+) C/T downstream_transcript_variant
rs1003096030 -- 3,128,279(+) C/T downstream_transcript_variant
rs1003181802 -- 3,127,890(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4251 Gene

Variant ID Type Subtype PubMed ID
nsv951959 CNV deletion 24416366
nsv545099 CNV loss 21841781
nsv428399 CNV gain 18775914
nsv1013792 CNV gain 25217958
nsv1000306 CNV gain 25217958
esv3585038 CNV gain 21293372
esv3583359 CNV gain 25503493
dgv11n100 CNV gain 25217958

Additional Variant Information for MIR4251 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4251 Gene

Disorders for MIR4251 Gene

Additional Disease Information for MIR4251

No disorders were found for MIR4251 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4251 Gene

Publications for MIR4251 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4251 Gene

Sources for MIR4251 Gene

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