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Aliases for MIR410 Gene

Subcategory (RNA class) for MIR410 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR410 Gene

  • MicroRNA 410 2 3 5
  • Hsa-Mir-410 3
  • Mir-410 3
  • MIRN410 3

External Ids for MIR410 Gene

ORGUL Members for MIR410 Gene

Previous HGNC Symbols for MIR410 Gene

  • MIRN410

Previous GeneCards Identifiers for MIR410 Gene

  • GC14P100843
  • GC14P100933
  • GC14P101534
  • GC14P101562
  • GC14P101595
  • GC14P101634
  • GC14P101662
  • GC14P101696
  • GC14P101734
  • GC14P101774
  • GC14P101832
  • GC14P101972
  • GC14P102169
  • GC14P101276
  • GC14P101895
  • GC14P102209
  • GC14P102376
  • GC14P102556
  • GC14P102728
  • GC14P102898

Summaries for MIR410 Gene

Entrez Gene Summary for MIR410 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR410 Gene

MIR410 (MicroRNA 410) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

Additional gene information for MIR410 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR410 Gene

Genomics for MIR410 Gene

GeneHancer (GH) Regulatory Elements for MIR410 Gene

Promoters and enhancers for MIR410 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I101096 Enhancer 0.7 FANTOM5 ENCODE 11.4 +32.4 32436 3.2 ATF4 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR410 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR410 Gene

Genomic Locations for MIR410 Gene
chr14:101,065,912-101,065,991
(GRCh38/hg38)
Size:
80 bases
Orientation:
Plus strand
chr14:101,532,249-101,532,328
(GRCh37/hg19)

Genomic View for MIR410 Gene

Genes around MIR410 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR410 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR410 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR410 Gene

Proteins for MIR410 Gene

Post-translational modifications for MIR410 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR410 Gene

Domains & Families for MIR410 Gene

Gene Families for MIR410 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR410: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR410 Gene

Function for MIR410 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR410 Gene

Localization for MIR410 Gene

Gene Ontology (GO) - Cellular Components for MIR410 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR410: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR410 Gene

Pathways & Interactions for MIR410 Gene

genes like me logo Genes that share pathways with MIR410: view

Pathways by source for MIR410 Gene

1 BioSystems pathway for MIR410 Gene

Interacting Proteins for MIR410 Gene

Gene Ontology (GO) - Biological Process for MIR410 Gene

None

No data available for SIGNOR curated interactions for MIR410 Gene

Drugs & Compounds for MIR410 Gene

No Compound Related Data Available

Transcripts for MIR410 Gene

mRNA/cDNA for MIR410 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR410 Gene

No ASD Table

Relevant External Links for MIR410 Gene

GeneLoc Exon Structure for
MIR410
ECgene alternative splicing isoforms for
MIR410

Expression for MIR410 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR410 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR410 Gene:

MIR410
genes like me logo Genes that share expression patterns with MIR410: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR410 Gene

Orthologs for MIR410 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR410 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-410 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-410 34
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir410 34
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-410 34
  • 65 (a)
OneToOne
Species where no ortholog for MIR410 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR410 Gene

ENSEMBL:
Gene Tree for MIR410 (if available)
TreeFam:
Gene Tree for MIR410 (if available)

Paralogs for MIR410 Gene

No data available for Paralogs for MIR410 Gene

Variants for MIR410 Gene

Sequence variations from dbSNP and Humsavar for MIR410 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000697312 -- 101,066,260(+) G/C downstream_transcript_variant
rs1003049499 -- 101,065,113(+) G/T upstream_transcript_variant
rs1003932318 -- 101,064,797(+) C/T upstream_transcript_variant
rs1004937700 -- 101,065,745(+) G/A upstream_transcript_variant
rs1006160079 -- 101,064,852(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR410 Gene

Variant ID Type Subtype PubMed ID
nsv565860 CNV gain 21841781
nsv565859 CNV gain 21841781
nsv509551 CNV insertion 20534489
nsv1040993 CNV gain 25217958
esv3635521 CNV gain 21293372

Additional Variant Information for MIR410 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR410

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR410 Gene

Disorders for MIR410 Gene

Additional Disease Information for MIR410

No disorders were found for MIR410 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR410 Gene

Publications for MIR410 Gene

  1. MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma. (PMID: 28138700) Chen R … Hu W (Molecular medicine reports 2017) 3 58
  2. MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer. (PMID: 28076327) Ke X … Wei Y (Oncotarget 2017) 3 58
  3. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  4. MicroRNA-410 acts as oncogene in NSCLC through downregulating SLC34A2 via activating Wnt/β-catenin pathway. (PMID: 26910912) Zhang X … Wei Y (Oncotarget 2016) 3 58
  5. Long non-coding RNA CCAT1 promotes glioma cell proliferation via inhibiting microRNA-410. (PMID: 27765628) Wang ZH … Zheng DL (Biochemical and biophysical research communications 2016) 3 58

Products for MIR410 Gene

Sources for MIR410 Gene

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