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Aliases for MIR3973 Gene

Subcategory (RNA class) for MIR3973 Gene


Quality Score for this RNA gene is


Aliases for MIR3973 Gene

  • MicroRNA 3973 2 3 5
  • Hsa-Mir-3973 3

External Ids for MIR3973 Gene

Previous GeneCards Identifiers for MIR3973 Gene

  • GC11U901866

Summaries for MIR3973 Gene

Entrez Gene Summary for MIR3973 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3973 Gene

MIR3973 (MicroRNA 3973) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3973 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3973 Gene

Genomics for MIR3973 Gene

GeneHancer (GH) Regulatory Elements for MIR3973 Gene

Promoters and enhancers for MIR3973 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I036008 Enhancer 1.1 Ensembl ENCODE dbSUPER 550.8 -0.9 -921 3.3 JUN RAD21 RFX5 CTBP1 GATA3 POLR2A FOSL2 FOS SMARCE1 CEBPB MIR3973 LDLRAD3 CD44 RPL12P31
GH11I036011 Enhancer 0.8 Ensembl ENCODE 0.8 +2.5 2483 1.3 BCOR TSC22D4 CEBPB DPF2 FOSL1 ZNF217 MAFF GATA3 JUND ADNP LDLRAD3 MIR3973 GC11M036020
GH11I036007 Enhancer 0.5 ENCODE 0.8 -2.6 -2589 0 SMARCE1 ZNF217 CTBP1 GATA3 DPF2 FOS SP7 LDLRAD3 MIR3973 RPL12P31
GH11I036014 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.4 +5.5 5514 2.2 MEIS2 ZFHX2 GATA3 CEBPB EGR2 LDLRAD3 MIR3973 GC11M036020
GH11I036030 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +21.0 21011 1.8 ATF4 GATA3 IKZF1 FOXP2 GC11M036020 MIR3973 LDLRAD3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3973 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3973 Gene

Genomic Locations for MIR3973 Gene
107 bases
Plus strand

Genomic View for MIR3973 Gene

Genes around MIR3973 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3973 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3973 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3973 Gene

Proteins for MIR3973 Gene

Post-translational modifications for MIR3973 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3973 Gene

Domains & Families for MIR3973 Gene

Gene Families for MIR3973 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3973: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3973 Gene

Function for MIR3973 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3973 Gene

Localization for MIR3973 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3973 Gene

Pathways & Interactions for MIR3973 Gene

SuperPathways for MIR3973 Gene

No Data Available

Interacting Proteins for MIR3973 Gene

Gene Ontology (GO) - Biological Process for MIR3973 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR3973 Gene

Drugs & Compounds for MIR3973 Gene

No Compound Related Data Available

Transcripts for MIR3973 Gene

mRNA/cDNA for MIR3973 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3973 Gene

No ASD Table

Relevant External Links for MIR3973 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3973 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3973 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3973 Gene:

genes like me logo Genes that share expression patterns with MIR3973: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3973 Gene

Orthologs for MIR3973 Gene

Evolution for MIR3973 Gene

Gene Tree for MIR3973 (if available)
Gene Tree for MIR3973 (if available)

No data available for Orthologs for MIR3973 Gene

Paralogs for MIR3973 Gene

No data available for Paralogs for MIR3973 Gene

Variants for MIR3973 Gene

Sequence variations from dbSNP and Humsavar for MIR3973 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000700237 -- 36,009,537(+) A/G upstream_transcript_variant
rs1001218998 -- 36,009,765(+) A/G upstream_transcript_variant
rs1002082108 -- 36,008,840(+) T/C upstream_transcript_variant
rs1002483245 -- 36,009,123(+) C/T upstream_transcript_variant
rs1002628126 -- 36,008,878(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3973 Gene

Variant ID Type Subtype PubMed ID
nsv832122 CNV gain 17160897
nsv7735 CNV insertion 18451855
nsv554002 CNV loss 21841781
nsv1042014 CNV loss 25217958
esv2422305 CNV duplication 17116639

Additional Variant Information for MIR3973 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3973 Gene

Disorders for MIR3973 Gene

Additional Disease Information for MIR3973

No disorders were found for MIR3973 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3973 Gene

Publications for MIR3973 Gene

  1. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. (PMID: 20876853) Ramsingh G … Link DC (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3973 Gene

Sources for MIR3973 Gene

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