Aliases for MIR3960 Gene
Subcategory (RNA class) for MIR3960 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR3960 Gene
- HGNC: 41595
- Entrez Gene: 100616250
- Ensembl: ENSG00000283863
- miRBase: hsa-mir-3960
Previous GeneCards Identifiers for MIR3960 Gene
- GC09U901725
- GC09P130553
- GC09P130554
- GC09P130557
Summaries for MIR3960 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR3960 Gene
MIR3960 (MicroRNA 3960) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Gene Expression.
Additional gene information for MIR3960 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3960 Gene
Genomics for MIR3960 Gene
GeneHancer (GH) Regulatory Elements for MIR3960 Gene
Promoters and enhancers for MIR3960 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH09I127775 | Promoter/Enhancer | 2.5 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 0.8 | -2.9 | -2934 | 13.9 | HDGF PKNOX1 CLOCK SMAD1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 | SH2D3C CDK9 FPGS LOC102723566 SNORA65 RPL12 URM1 ZNF79 ZBTB34 TOR2A |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR3960 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR3960 Gene
Genomic Locations for MIR3960 Gene
- chr9:127,785,833-127,785,923
- (GRCh38/hg38)
- Size:
- 91 bases
- Orientation:
- Plus strand
- chr9:130,548,112-130,548,202
- (GRCh37/hg19)
Genomic View for MIR3960 Gene
Genes around MIR3960 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.11 by Ensembl
- 9q34.11 by Entrez Gene
- 9q34.11 by HGNC
MIR3960 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR3960 Gene
Proteins for MIR3960 Gene
Post-translational modifications for MIR3960 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR3960
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3960
- Origene Custom Protein Services for MIR3960
- Search GeneTex for Proteins for MIR3960
No data available for DME Specific Peptides for MIR3960 Gene
Domains & Families for MIR3960 Gene
Gene Families for MIR3960 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3960 Gene
Function for MIR3960 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR3960
-
- Search ViGene Biosciences for MIR3960
CRISPR Products
- Browse CRISPR knockouts for MIR3960
- Applied Biological Materials CRISPR for MIR3960
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR3960
Clone Products
- GenScript: Custom all cDNA clones Services for MIR3960
- VectorBuilder custom plasmid, inducible vectors for MIR3960
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR3960
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR3960
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3960 Gene
Localization for MIR3960 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3960 Gene
Pathways & Interactions for MIR3960 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Formation of HIV elongation complex in the absence of HIV Tat | ||
| 2 | HIV Life Cycle |
.92
.65
|
.45
|
| 3 | Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer | ||
| 4 | Gene Expression |
.48
|
|
| 5 | MicroRNAs in cardiomyocyte hypertrophy | ||
Pathways by source for MIR3960 Gene
4 BioSystems pathways for MIR3960 Gene
Interacting Proteins for MIR3960 Gene
No data available for SIGNOR curated interactions for MIR3960 Gene
Transcripts for MIR3960 Gene
mRNA/cDNA for MIR3960 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR3960
- Applied Biological Materials CRISPR for MIR3960
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR3960
Clone Products
- GenScript: Custom all cDNA clones Services for MIR3960
- VectorBuilder custom plasmid, inducible vectors for MIR3960
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR3960
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR3960
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR3960 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR3960 Gene:
MIR3960Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3960 Gene
Orthologs for MIR3960 Gene
No data available for Orthologs for MIR3960 Gene
Paralogs for MIR3960 Gene
No data available for Paralogs for MIR3960 Gene
Variants for MIR3960 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs794728003 | association, Bone mineral density quantitative trait locus 15 | 127,785,950(+) | C/G | downstream_transcript_variant | |
| rs1000622607 | -- | 127,784,616(+) | G/A/T | upstream_transcript_variant | |
| rs1000911478 | -- | 127,784,670(+) | T/G | upstream_transcript_variant | |
| rs1000925389 | -- | 127,784,697(+) | G/C | upstream_transcript_variant | |
| rs1002805270 | -- | 127,785,314(+) | G/A | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv825094 | CNV | gain | 20364138 |
| nsv615374 | CNV | loss | 21841781 |
| nsv615373 | CNV | loss | 21841781 |
| nsv615371 | CNV | loss | 21841781 |
| nsv471323 | CNV | loss | 18288195 |
| nsv466575 | CNV | loss | 19166990 |
| nsv466573 | CNV | loss | 19166990 |
| nsv1075676 | CNV | deletion | 25765185 |
| esv3891727 | CNV | gain | 25118596 |
| dgv12879n54 | CNV | loss | 21841781 |
Additional Variant Information for MIR3960 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR3960
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3960 Gene
Disorders for MIR3960 Gene
Additional Disease Information for MIR3960
No disorders were found for MIR3960 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3960 Gene
Publications for MIR3960 Gene
- A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation. (PMID: 21324897) Hu R … Luo XH (The Journal of biological chemistry 2011) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR3960 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3960
- Origene Custom Protein Services for MIR3960
- Browse OriGene Inhibitory RNA Products For MIR3960
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR3960
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR3960
- GenScript: Custom all cDNA clones Services for MIR3960
- GenScript Custom Purified and Recombinant Proteins Services for MIR3960
- GenScript Custom Assay Services for MIR3960
- GenScript Custom overexpressing Cell Line Services for MIR3960
- Browse GenScript CRISPR for MIR3960
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR3960
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR3960
- VectorBuilder custom plasmid, inducible vectors for MIR3960
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR3960
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR3960
- Search GeneTex for Proteins for MIR3960
Sources for MIR3960 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew