microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3960 Gene

Subcategory (RNA class) for MIR3960 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR3960 Gene

  • MicroRNA 3960 2 3 5
  • Hsa-Mir-3960 2 3
  • MIR3960 2 5
  • Hsa-MiR-3960 173
  • MIMAT0019337 50
  • MI0016964 50

External Ids for MIR3960 Gene

Previous GeneCards Identifiers for MIR3960 Gene

  • GC09U901725
  • GC09P130553
  • GC09P130554
  • GC09P130557
  • GC09P127786

Summaries for MIR3960 Gene

Entrez Gene Summary for MIR3960 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3960 Gene

MIR3960 (MicroRNA 3960) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Signaling by GPCR.

Additional gene information for MIR3960 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3960 Gene

Genomics for MIR3960 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3960 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J127775 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -3.1 -3105 14.3 SP1 CTCF PRDM10 ZNF629 RFX1 SIX5 LEF1 IKZF1 KDM1A ZNF692 SH2D3C CDK9 lnc-CDK9-1 FPGS LOC102723566 SNORA65 RPL12 URM1 ZNF79 ENSG00000228510
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3960 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3960 Gene

Genomic Locations for MIR3960 Gene
chr9:127,785,833-127,785,923
(GRCh38/hg38)
Size:
91 bases
Orientation:
Plus strand
chr9:130,548,112-130,548,202
(GRCh37/hg19)
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR3960 Gene

Genes around MIR3960 on UCSC Golden Path with GeneCards custom track
MIR3960 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3960 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3960 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3960 Gene

Proteins for MIR3960 Gene

Post-translational modifications for MIR3960 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3960 Gene

Domains & Families for MIR3960 Gene

Gene Families for MIR3960 Gene

HGNC:
genes like me logo Genes that share domains with MIR3960: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3960 Gene

Function for MIR3960 Gene

Phenotypes From GWAS Catalog for MIR3960 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3960 Gene

Localization for MIR3960 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3960 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3960 Gene

Pathways & Interactions for MIR3960 Gene

genes like me logo Genes that share pathways with MIR3960: view

Gene Ontology (GO) - Biological Process for MIR3960 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3960 Gene

Drugs & Compounds for MIR3960 Gene

No Compound Related Data Available

Transcripts for MIR3960 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3960 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CBCF_9606 precursor_RNA 91 4

HGNC: 41595,

RefSeq: NR_039767,

Ensembl: ENST00000583311 (view in UCSC) ,

miRBase: MI0016964,

URS00003783AB_9606 miRNA 20 3

RefSeq: NR_039767,

miRBase: MIMAT0019337,

TarBase: hsa-miR-3960,

MIR3960 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3960 Gene

No ASD Table

Relevant External Links for MIR3960 Gene

GeneLoc Exon Structure for
MIR3960

No data available for mRNA/cDNA for MIR3960 Gene

Expression for MIR3960 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3960 Gene

genes like me logo Genes that share expression patterns with MIR3960: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3960 Gene

Orthologs for MIR3960 Gene

Evolution for MIR3960 Gene

ENSEMBL:
Gene Tree for MIR3960 (if available)
TreeFam:
Gene Tree for MIR3960 (if available)

No data available for Orthologs for MIR3960 Gene

Paralogs for MIR3960 Gene

No data available for Paralogs for MIR3960 Gene

Variants for MIR3960 Gene

Additional dbSNP identifiers (rs#s) for MIR3960 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3960 Gene

Variant ID Type Subtype PubMed ID
dgv12879n54 CNV loss 21841781
esv3891727 CNV gain 25118596
nsv1075676 CNV deletion 25765185
nsv466573 CNV loss 19166990
nsv466575 CNV loss 19166990
nsv471323 CNV loss 18288195
nsv615371 CNV loss 21841781
nsv615373 CNV loss 21841781
nsv615374 CNV loss 21841781
nsv825094 CNV gain 20364138

Additional Variant Information for MIR3960 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3960

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3960 Gene

Disorders for MIR3960 Gene

Additional Disease Information for MIR3960

No disorders were found for MIR3960 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3960 Gene

Publications for MIR3960 Gene

  1. A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation. (PMID: 21324897) Hu R … Luo XH (The Journal of biological chemistry 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3960 Gene

Sources for MIR3960 Gene