microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3926-1 Gene

Data sources for MIR3926-1 Gene:

RNA type for MIR3926-1 Gene

miRNA

Aliases for MIR3926-1 Gene

External Ids for MIR3926-1 Gene

Previous GeneCards Identifiers for MIR3926-1 Gene

  • GC08U901484
  • GC08M012585

Summaries for MIR3926-1 Gene

Entrez Gene Summary for MIR3926-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3926-1 Gene

MIR3926-1 (MicroRNA 3926-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3926-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3926-1 Gene

Genomics for MIR3926-1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3926-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J012725 Enhancer 1 Ensembl ENCODE 250.7 +0.6 604 2.6 JUND CEBPA CEBPB EP300 FOXA2 MAFF SAP130 ZNF316 TEAD3 TCF7L2 MIR3926-1 MIR3926-2 lnc-FAM86B2-6 microRNAhsa-miR-3926-2-3p LONRF1 FAM86B2
GH08J012731 Enhancer 0.4 Ensembl 0.4 -5.6 -5597 3.4 CTCF POLR2A RUNX3 ZFHX2 LONRF1 ENPP7P12 lnc-FAM86B2-7 MIR3926-1 FAM86B2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3926-1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3926-1 Gene

Latest Assembly
chr8:12,727,232-12,727,304
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand

Previous Assembly
chr8:12,584,741-12,584,813
(GRCh37/hg19 by Entrez Gene)
Size:
73 bases
Orientation:
Minus strand

chr8:12,584,741-12,584,813
(GRCh37/hg19 by Ensembl)
Size:
73 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr8(PATCHES):5,922,580-5,922,652 (-)

Genomic View for MIR3926-1 Gene

Genes around MIR3926-1 on UCSC Golden Path with GeneCards custom track
MIR3926-1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3926-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3926-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3926-1 Gene

Proteins for MIR3926-1 Gene

Post-translational modifications for MIR3926-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3926-1 Gene

Domains & Families for MIR3926-1 Gene

Gene Families for MIR3926-1 Gene

HGNC:
genes like me logo Genes that share domains with MIR3926-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3926-1 Gene

Function for MIR3926-1 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3926-1 Gene

Localization for MIR3926-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3926-1 Gene

Pathways & Interactions for MIR3926-1 Gene

PathCards logo

SuperPathways for MIR3926-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3926-1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3926-1 Gene

Drugs & Compounds for MIR3926-1 Gene

No Compound Related Data Available

Transcripts for MIR3926-1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3926-1 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075B286_9606 precursor_RNA 73 4

RefSeq: NR_037492,

Ensembl: ENST00000578598 (view in UCSC) ,

miRBase: MI0016434,

ENA: LM611257.1:1..73:precursor_RNA,

URS0000576DFF_9606 miRNA 21 3

RefSeq: NR_037492, NR_037495,

miRBase: MIMAT0018201,

ENA: LM382177.1:1..21:ncRNA, LM611257.1:11..31:ncRNA, LM611259.1:6..26:ncRNA,

MIR3926-1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3926-1 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3926-1 Gene

No ASD Table

Relevant External Links for MIR3926-1 Gene

GeneLoc Exon Structure for
MIR3926-1

Expression for MIR3926-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3926-1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3926-1

genes like me logo Genes that share expression patterns with MIR3926-1: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3926-1 Gene

Orthologs for MIR3926-1 Gene

Evolution for MIR3926-1 Gene

ENSEMBL:
Gene Tree for MIR3926-1 (if available)
TreeFam:
Gene Tree for MIR3926-1 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3926-1

No data available for Orthologs for MIR3926-1 Gene

Paralogs for MIR3926-1 Gene

No data available for Paralogs for MIR3926-1 Gene

Variants for MIR3926-1 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3926-1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3926-1 Gene

Variant ID Type Subtype PubMed ID
dgv244e55 CNV gain 17911159
dgv246e55 CNV gain 17911159
esv2759593 CNV gain+loss 17122850
nsv1029648 CNV gain 25217958

Additional Variant Information for MIR3926-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3926-1
Leiden Open Variation Database (LOVD)
MIR3926-1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3926-1 Gene

Disorders for MIR3926-1 Gene

Additional Disease Information for MIR3926-1

No disorders were found for MIR3926-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3926-1 Gene

Publications for MIR3926-1 Gene

  1. MiR-3926 inhibits synovial fibroblasts proliferation and inflammatory cytokines secretion through targeting toll like receptor 5. (PMID: 30412746) Fu D … Ye S (Gene 2019) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3926-1 Gene

Sources for MIR3926-1 Gene