microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3917 Gene

Subcategory (RNA class) for MIR3917 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR3917 Gene

  • MicroRNA 3917 2 3 5
  • Hsa-Mir-3917 2 3
  • MIR3917 2 5
  • Hsa-MiR-3917 173
  • MIMAT0018191 50
  • MI0016423 50
  • Mir-3917 3

External Ids for MIR3917 Gene

Previous GeneCards Identifiers for MIR3917 Gene

  • GC01U903123
  • GC01M026237
  • GC01M026243
  • GC01M026246
  • GC01M025885

Summaries for MIR3917 Gene

Entrez Gene Summary for MIR3917 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3917 Gene

MIR3917 (MicroRNA 3917) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are EGF/EGFR Signaling Pathway and Retinoblastoma (RB) in Cancer.

Additional gene information for MIR3917 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3917 Gene

Genomics for MIR3917 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3917 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J025903 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +0.9 910 5.1 SP1 HNRNPL CREB1 ATF7 PRDM10 ZNF629 TFE3 SIX5 LEF1 ZNF692 LOC105376885 MIR3917 STMN1 lnc-PAQR7-1 piR-52220 GPN2 MTFR1L ENSG00000261349 PIGV DHDDS-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3917 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3917 Gene

Genomic Locations for MIR3917 Gene
chr1:25,906,362-25,906,454
(GRCh38/hg38)
Size:
93 bases
Orientation:
Minus strand
chr1:26,232,853-26,232,945
(GRCh37/hg19)
Size:
93 bases
Orientation:
Minus strand

Genomic View for MIR3917 Gene

Genes around MIR3917 on UCSC Golden Path with GeneCards custom track
MIR3917 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3917 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3917 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3917 Gene

Proteins for MIR3917 Gene

Post-translational modifications for MIR3917 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3917 Gene

Domains & Families for MIR3917 Gene

Gene Families for MIR3917 Gene

HGNC:
genes like me logo Genes that share domains with MIR3917: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3917 Gene

Function for MIR3917 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3917 Gene

Localization for MIR3917 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3917 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3917 Gene

Pathways & Interactions for MIR3917 Gene

genes like me logo Genes that share pathways with MIR3917: view

Pathways by source for MIR3917 Gene

Gene Ontology (GO) - Biological Process for MIR3917 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3917 Gene

Drugs & Compounds for MIR3917 Gene

No Compound Related Data Available

Transcripts for MIR3917 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3917 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BB4E_9606 precursor_RNA 93 5

HGNC: 38911,

RefSeq: NR_037481,

Ensembl: ENST00000580971 (view in UCSC) ,

miRBase: MI0016423,

ENA: LM611253.1:1..93:precursor_RNA,

URS000035925E_9606 miRNA 20 4

RefSeq: NR_037481,

miRBase: MIMAT0018191,

TarBase: hsa-miR-3917,

ENA: LM382174.1:1..20:ncRNA, LM611253.1:52..71:ncRNA,

MIR3917 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3917 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3917 Gene

No ASD Table

Relevant External Links for MIR3917 Gene

GeneLoc Exon Structure for
MIR3917

Expression for MIR3917 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3917 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3917 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x5.8), Brain - Frontal Cortex (BA9) (x5.3), Brain - Anterior cingulate cortex (BA24) (x5.0), and Brain - Cortex (x4.4).
genes like me logo Genes that share expression patterns with MIR3917: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3917 Gene

Orthologs for MIR3917 Gene

Evolution for MIR3917 Gene

ENSEMBL:
Gene Tree for MIR3917 (if available)
TreeFam:
Gene Tree for MIR3917 (if available)

No data available for Orthologs for MIR3917 Gene

Paralogs for MIR3917 Gene

No data available for Paralogs for MIR3917 Gene

Variants for MIR3917 Gene

Additional dbSNP identifiers (rs#s) for MIR3917 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3917 Gene

Variant ID Type Subtype PubMed ID
nsv834491 CNV loss 17160897
nsv834502 CNV gain 17160897

Additional Variant Information for MIR3917 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3917

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3917 Gene

Disorders for MIR3917 Gene

Additional Disease Information for MIR3917

No disorders were found for MIR3917 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3917 Gene

Publications for MIR3917 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3917 Gene

Sources for MIR3917 Gene