microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3910-2 Gene

Subcategory (RNA class) for MIR3910-2 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR3910-2 Gene

  • MicroRNA 3910-2 2 3 5
  • Hsa-Mir-3910-2 2 3
  • MIR3910-2 2 5
  • MIMAT0018184 50
  • Mir-3910-2 3
  • MI0016431 50

External Ids for MIR3910-2 Gene

Previous GeneCards Identifiers for MIR3910-2 Gene

  • GC09U901634
  • GC09P094400
  • GC09M094399

Summaries for MIR3910-2 Gene

Entrez Gene Summary for MIR3910-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3910-2 Gene

MIR3910-2 (MicroRNA 3910-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3910-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3910-2 Gene

Genomics for MIR3910-2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3910-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J091659 Enhancer 0.6 Ensembl 0.4 -23.8 -23756 1 CTCF REST FOXA2 RAD21 ZNF654 HNF4A RXRA SMC3 TRIM22 SP1 ENSG00000228216 lnc-CENPP-15 MIR3910-2 NFIL3 ROR2
GH09J091661 Enhancer 0.3 Ensembl 0.3 -25.9 -25856 1.2 SPI1 lnc-CENPP-15 MIR3910-2 NFIL3 ROR2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3910-2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3910-2 Gene

Genomic Locations for MIR3910-2 Gene
chr9:91,636,264-91,636,345
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand
chr9:94,398,546-94,398,627
(GRCh37/hg19)
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR3910-2 Gene

Genes around MIR3910-2 on UCSC Golden Path with GeneCards custom track
MIR3910-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3910-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3910-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3910-2 Gene

Proteins for MIR3910-2 Gene

Post-translational modifications for MIR3910-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3910-2 Gene

Domains & Families for MIR3910-2 Gene

Gene Families for MIR3910-2 Gene

HGNC:
genes like me logo Genes that share domains with MIR3910-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3910-2 Gene

Function for MIR3910-2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3910-2 Gene

Localization for MIR3910-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3910-2 Gene

Pathways & Interactions for MIR3910-2 Gene

PathCards logo

SuperPathways for MIR3910-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3910-2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3910-2 Gene

Drugs & Compounds for MIR3910-2 Gene

No Compound Related Data Available

Transcripts for MIR3910-2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3910-2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C036_9606 precursor_RNA 82 5

HGNC: 38952,

RefSeq: NR_037489,

Ensembl: ENST00000636558 (view in UCSC) ,

miRBase: MI0016431,

ENA: LM611256.1:1..82:precursor_RNA,

URS00003E1C37_9606 miRNA 20 3

RefSeq: NR_037472, NR_037489,

miRBase: MIMAT0018184,

ENA: LM382168.1:1..20:ncRNA, LM611246.1:63..82:ncRNA, LM611256.1:50..69:ncRNA,

MIR3910-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3910-2 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3910-2 Gene

No ASD Table

Relevant External Links for MIR3910-2 Gene

GeneLoc Exon Structure for
MIR3910-2

Expression for MIR3910-2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3910-2

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3910-2 Gene

Orthologs for MIR3910-2 Gene

Evolution for MIR3910-2 Gene

ENSEMBL:
Gene Tree for MIR3910-2 (if available)
TreeFam:
Gene Tree for MIR3910-2 (if available)

No data available for Orthologs for MIR3910-2 Gene

Paralogs for MIR3910-2 Gene

No data available for Paralogs for MIR3910-2 Gene

Variants for MIR3910-2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR3910-2 Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
157151 Not Provided: Normal pregnancy 91,633,776(-) TGTACATAGGCAGAAC

Additional dbSNP identifiers (rs#s) for MIR3910-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3910-2 Gene

Variant ID Type Subtype PubMed ID
dgv12792n54 CNV loss 21841781
dgv12793n54 CNV loss 21841781
esv2671891 CNV deletion 23128226
esv3545125 CNV deletion 23714750
esv3584916 CNV loss 24956385
esv3621067 CNV loss 21293372
nsv1045332 CNV loss 25217958
nsv438109 CNV loss 16468122
nsv516473 CNV loss 19592680
nsv614860 CNV loss 21841781
nsv614863 CNV loss 21841781
nsv818713 CNV loss 17921354

Additional Variant Information for MIR3910-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3910-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3910-2 Gene

Disorders for MIR3910-2 Gene

Additional Disease Information for MIR3910-2

No disorders were found for MIR3910-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3910-2 Gene

Publications for MIR3910-2 Gene

  1. A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. (PMID: 28625976) Hou P … Huang J (Cancer research 2017) 3
  2. MiR-3910 Promotes the Growth and Migration of Cancer Cells in the Progression of Hepatocellular Carcinoma. (PMID: 28823082) Cheng L … Han S (Digestive diseases and sciences 2017) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3910-2 Gene

Sources for MIR3910-2 Gene