microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3908 Gene

Subcategory (RNA class) for MIR3908 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR3908 Gene

  • MicroRNA 3908 2 3 5
  • Hsa-Mir-3908 3
  • MIMAT0018182 53
  • MI0016412 53
  • MIR3908 2

External Ids for MIR3908 Gene

Previous GeneCards Identifiers for MIR3908 Gene

  • GC12U901507
  • GC12P124022

Summaries for MIR3908 Gene

Entrez Gene Summary for MIR3908 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3908 Gene

MIR3908 (MicroRNA 3908) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3908 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3908 Gene

Genomics for MIR3908 Gene

Genomic Locations for MIR3908 Gene

Genomic Locations for MIR3908 Gene
chr12:123,536,409-123,536,534
(GRCh38/hg38)
Size:
126 bases
Orientation:
Plus strand
chr12:124,020,956-124,021,081
(GRCh37/hg19)
Size:
126 bases
Orientation:
Plus strand

Genomic View for MIR3908 Gene

Genes around MIR3908 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3908 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3908 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3908 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR3908 Gene

Proteins for MIR3908 Gene

Post-translational modifications for MIR3908 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3908 Gene

Domains & Families for MIR3908 Gene

Gene Families for MIR3908 Gene

HGNC:
genes like me logo Genes that share domains with MIR3908: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3908 Gene

Function for MIR3908 Gene

Phenotypes From GWAS Catalog for MIR3908 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3908 Gene

Localization for MIR3908 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3908 Gene

Pathways & Interactions for MIR3908 Gene

PathCards logo

SuperPathways for MIR3908 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3908 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3908 Gene

Drugs & Compounds for MIR3908 Gene

No Compound Related Data Available

Transcripts for MIR3908 Gene

mRNA/cDNA for MIR3908 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3908 Gene

No ASD Table

Relevant External Links for MIR3908 Gene

GeneLoc Exon Structure for
MIR3908
ECgene alternative splicing isoforms for
MIR3908

Expression for MIR3908 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3908 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3908 Gene:

MIR3908
genes like me logo Genes that share expression patterns with MIR3908: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3908 Gene

Orthologs for MIR3908 Gene

Evolution for MIR3908 Gene

ENSEMBL:
Gene Tree for MIR3908 (if available)
TreeFam:
Gene Tree for MIR3908 (if available)

No data available for Orthologs for MIR3908 Gene

Paralogs for MIR3908 Gene

No data available for Paralogs for MIR3908 Gene

Variants for MIR3908 Gene

Sequence variations from dbSNP and Humsavar for MIR3908 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001974179 -- 123,536,795(+) T/G downstream_transcript_variant
rs1002602881 -- 123,534,975(+) T/C upstream_transcript_variant
rs1003526091 -- 123,535,764(+) T/C upstream_transcript_variant
rs1005802420 -- 123,536,559(+) C/G downstream_transcript_variant
rs1006022636 -- 123,534,635(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3908 Gene

Variant ID Type Subtype PubMed ID
esv2422416 CNV duplication 17116639
nsv1037260 CNV gain 25217958

Additional Variant Information for MIR3908 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3908

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3908 Gene

Disorders for MIR3908 Gene

Additional Disease Information for MIR3908

No disorders were found for MIR3908 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3908 Gene

Publications for MIR3908 Gene

  1. AdipoR1-mediated miR-3908 inhibits glioblastoma tumorigenicity through downregulation of STAT2 associated with the AMPK/SIRT1 pathway. (PMID: 28440504) Liu X … Zhang J (Oncology reports 2017) 3 56
  2. Lipid raft-mediated miR-3908 inhibition of migration of breast cancer cell line MCF-7 by regulating the interactions between AdipoR1 and Flotillin-1. (PMID: 28327197) Li Y … Chen J (World journal of surgical oncology 2017) 3 56
  3. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 56
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR3908 Gene

Sources for MIR3908 Gene