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Aliases for MIR379 Gene

Subcategory (RNA class) for MIR379 Gene


Quality Score for this RNA gene is


Aliases for MIR379 Gene

  • MicroRNA 379 2 3 5
  • Hsa-Mir-379 3
  • Mir-379 3
  • MIRN379 3

External Ids for MIR379 Gene

ORGUL Members for MIR379 Gene

Previous HGNC Symbols for MIR379 Gene

  • MIRN379

Previous GeneCards Identifiers for MIR379 Gene

  • GC14P100811
  • GC14P100903
  • GC14P101488
  • GC14P101230
  • GC14P101801
  • GC14P102095
  • GC14P102329
  • GC14P102499
  • GC14P102676
  • GC14P102848
  • GC14P103023

Summaries for MIR379 Gene

Entrez Gene Summary for MIR379 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR379 Gene

MIR379 (MicroRNA 379) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR379 include Polymyositis and Dermatomyositis.

Additional gene information for MIR379 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR379 Gene

Genomics for MIR379 Gene

GeneHancer (GH) Regulatory Elements for MIR379 Gene

Promoters and enhancers for MIR379 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J101020 Enhancer 0.5 ENCODE 650.7 -1.1 -1081 1 KLF1 ZNF488 KLF8 ZNF248 ZBTB1 GC14P103382 MIR379 MEG9 ENSG00000222185 MEG8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR379 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR379 Gene

Genomic Locations for MIR379 Gene
67 bases
Plus strand
126 bases
Plus strand

Genomic View for MIR379 Gene

Genes around MIR379 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR379 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR379 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR379 Gene

Proteins for MIR379 Gene

Post-translational modifications for MIR379 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR379 Gene

Domains & Families for MIR379 Gene

Gene Families for MIR379 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR379: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR379 Gene

Function for MIR379 Gene

Phenotypes From GWAS Catalog for MIR379 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR379 Gene

Localization for MIR379 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR379 Gene

Pathways & Interactions for MIR379 Gene

SuperPathways for MIR379 Gene

No Data Available

Interacting Proteins for MIR379 Gene

Gene Ontology (GO) - Biological Process for MIR379 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR379 Gene

Drugs & Compounds for MIR379 Gene

No Compound Related Data Available

Transcripts for MIR379 Gene

mRNA/cDNA for MIR379 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR379 Gene

No ASD Table

Relevant External Links for MIR379 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR379 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR379 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR379 Gene:

genes like me logo Genes that share expression patterns with MIR379: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR379 Gene

Orthologs for MIR379 Gene

Evolution for MIR379 Gene

Gene Tree for MIR379 (if available)
Gene Tree for MIR379 (if available)

No data available for Orthologs for MIR379 Gene

Paralogs for MIR379 Gene

No data available for Paralogs for MIR379 Gene

Variants for MIR379 Gene

Sequence variations from dbSNP and Humsavar for MIR379 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1001056043 -- 101,022,619(+) C/G downstream_transcript_variant
rs1001734264 -- 101,020,376(+) C/G upstream_transcript_variant
rs1003412680 -- 101,021,384(+) C/T upstream_transcript_variant
rs1003500241 -- 101,021,122(+) G/A/C upstream_transcript_variant
rs1003855846 -- 101,021,267(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR379 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv1426 CNV insertion 18451855
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR379 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR379 Gene

Disorders for MIR379 Gene

MalaCards: The human disease database

(4) MalaCards diseases for MIR379 Gene - From: miR2Disease

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR379

genes like me logo Genes that share disorders with MIR379: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR379 Gene

Publications for MIR379 Gene

  1. MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. (PMID: 27781416) Li Z … Wu WK (Journal of cellular and molecular medicine 2017) 3 58
  2. Suppression of EIF4G2 by miR-379 potentiates the cisplatin chemosensitivity in nonsmall cell lung cancer cells. (PMID: 28117895) Hao GJ … Zhang BB (FEBS letters 2017) 3 58
  3. MicroRNA-379 inhibits the proliferation, migration and invasion of human osteosarcoma cells by targetting EIF4G2. (PMID: 28381518) Xie X … Luo W (Bioscience reports 2017) 3 58
  4. MicroRNA-379-5p plays a tumor-suppressive role in human bladder cancer growth and metastasis by directly targeting MDM2. (PMID: 28498468) Wu D … Wang Z (Oncology reports 2017) 3 58
  5. MicroRNA-379 inhibits metastasis and epithelial-mesenchymal transition via targeting FAK/AKT signaling in gastric cancer. (PMID: 28713929) Xu M … Li M (International journal of oncology 2017) 3 58

Products for MIR379 Gene

Sources for MIR379 Gene

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