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Aliases for MIR378I Gene

Subcategory (RNA class) for MIR378I Gene


Quality Score for this RNA gene is


Aliases for MIR378I Gene

  • MicroRNA 378i 2 3 5
  • Hsa-Mir-378i 3

External Ids for MIR378I Gene

Previous GeneCards Identifiers for MIR378I Gene

  • GC22U900799
  • GC22M042322
  • GC22M041926
  • GC22M041928
  • GC22M042059

Summaries for MIR378I Gene

Entrez Gene Summary for MIR378I Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378I Gene

MIR378I (MicroRNA 378i) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System.

Additional gene information for MIR378I Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378I Gene

Genomics for MIR378I Gene

GeneHancer (GH) Regulatory Elements for MIR378I Gene

Promoters and enhancers for MIR378I Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I041918 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 -1.0 -1001 11 HDGF SMAD1 ZNF2 IRF4 ZNF121 GLIS2 ZNF207 ZNF143 ATF7 RUNX3 TNFRSF13C GC22M042615 MIR378I NDUFA6 SMDT1 CYP2D8P CSDC2 CENPM SHISA8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR378I on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR378I Gene

Genomic Locations for MIR378I Gene
76 bases
Minus strand

Genomic View for MIR378I Gene

Genes around MIR378I on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378I Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378I Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378I Gene

ORGUL Member Location for MIR378I Gene

ORGUL Member Location for MIR378I gene

Proteins for MIR378I Gene

Post-translational modifications for MIR378I Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378I Gene

Domains & Families for MIR378I Gene

Gene Families for MIR378I Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378I: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378I Gene

Function for MIR378I Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378I Gene

Localization for MIR378I Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR378I Gene

Pathways & Interactions for MIR378I Gene

No data available for SIGNOR curated interactions for MIR378I Gene

Drugs & Compounds for MIR378I Gene

No Compound Related Data Available

Transcripts for MIR378I Gene

mRNA/cDNA for MIR378I Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378I Gene

No ASD Table

Relevant External Links for MIR378I Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR378I Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR378I Gene

mRNA differential expression in normal tissues according to GTEx for MIR378I Gene

This gene is overexpressed in Spleen (x16.6), Small Intestine - Terminal Ileum (x9.4), and Whole Blood (x9.3).

NURSA nuclear receptor signaling pathways regulating expression of MIR378I Gene:

genes like me logo Genes that share expression patterns with MIR378I: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378I Gene

Orthologs for MIR378I Gene

Evolution for MIR378I Gene

Gene Tree for MIR378I (if available)
Gene Tree for MIR378I (if available)

No data available for Orthologs for MIR378I Gene

Paralogs for MIR378I Gene

No data available for Paralogs for MIR378I Gene

Variants for MIR378I Gene

Sequence variations from dbSNP and Humsavar for MIR378I Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs550105406 uncertain-significance, Common Variable Immune Deficiency, Recessive 41,925,254(-) C/T upstream_transcript_variant
rs7290134 benign, Common Variable Immune Deficiency, Recessive 41,925,247(-) A/G upstream_transcript_variant
rs1000160835 -- 41,923,555(-) GGGGGG/GGGGG/GGGGGGG upstream_transcript_variant
rs1000232273 -- 41,923,291(-) T/G non_coding_transcript_variant
rs1000780087 -- 41,925,209(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR378I Gene

Variant ID Type Subtype PubMed ID
nsv955162 CNV deletion 24416366
nsv589053 CNV loss 21841781
nsv508736 CNV insertion 20534489
nsv1057208 CNV gain 25217958

Additional Variant Information for MIR378I Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378I Gene

Disorders for MIR378I Gene

Additional Disease Information for MIR378I

No disorders were found for MIR378I Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378I Gene

Publications for MIR378I Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR378I Gene

Sources for MIR378I Gene

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