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Aliases for MIR378H Gene

Subcategory (RNA class) for MIR378H Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR378H Gene

  • MicroRNA 378h 2 3 5
  • Hsa-Mir-378h 3

External Ids for MIR378H Gene

Previous GeneCards Identifiers for MIR378H Gene

  • GC05U901576
  • GC05P154211

Summaries for MIR378H Gene

Entrez Gene Summary for MIR378H Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378H Gene

MIR378H (MicroRNA 378h) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR378H Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378H Gene

Genomics for MIR378H Gene

GeneHancer (GH) Regulatory Elements for MIR378H Gene

Promoters and enhancers for MIR378H Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I154828 Enhancer 1 ENCODE dbSUPER 550.8 +0.3 327 2.8 NCOA3 CTCF FOXA2 NFIB ZBTB7B RAD21 RARA ZNF121 CTBP1 GATA3 MIR378H CNOT8 FAXDC2 LARP1
GH05I154849 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 0.3 +21.3 21250 2.4 ARID4B ZNF2 YY1 ATF7 RXRA NFYC REST MIER2 PPARG ZNF592 FAXDC2 CNOT8 MIR378H
GH05I154834 Enhancer 1.5 Ensembl ENCODE dbSUPER 0.4 +5.6 5624 1.7 PKNOX1 FOXA2 MLX ARNT ARID4B FEZF1 ZNF2 YY1 ZNF766 ZNF213 CNOT8 SAP30L-AS1 LARP1 MFAP3 GEMIN5 FAM114A2 FAXDC2 MIR378H
GH05I154844 Enhancer 1.1 ENCODE dbSUPER 0.4 +15.5 15460 0.4 ELF3 PKNOX1 CLOCK ATF1 FOXA2 NFIB MLX ARID4B NEUROD1 FOS CNOT8 FAXDC2 MIR378H
GH05I154843 Enhancer 0.9 ENCODE 0.4 +13.7 13698 0.2 ELF3 FOXA2 MLX ARID4B DMAP1 RARA CREM THAP11 MIXL1 HMG20B CNOT8 MIR378H FAXDC2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR378H on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR378H Gene

Genomic Locations for MIR378H Gene
chr5:154,829,458-154,829,540
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr5:154,209,018-154,209,100
(GRCh37/hg19)

Genomic View for MIR378H Gene

Genes around MIR378H on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378H Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378H Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378H Gene

Proteins for MIR378H Gene

Post-translational modifications for MIR378H Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378H Gene

Domains & Families for MIR378H Gene

Gene Families for MIR378H Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378H: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378H Gene

Function for MIR378H Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378H Gene

Localization for MIR378H Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR378H Gene

Pathways & Interactions for MIR378H Gene

SuperPathways for MIR378H Gene

No Data Available

Interacting Proteins for MIR378H Gene

Gene Ontology (GO) - Biological Process for MIR378H Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR378H Gene

Drugs & Compounds for MIR378H Gene

No Compound Related Data Available

Transcripts for MIR378H Gene

mRNA/cDNA for MIR378H Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378H Gene

No ASD Table

Relevant External Links for MIR378H Gene

GeneLoc Exon Structure for
MIR378H
ECgene alternative splicing isoforms for
MIR378H

Expression for MIR378H Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR378H Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378H Gene:

MIR378H
genes like me logo Genes that share expression patterns with MIR378H: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378H Gene

Orthologs for MIR378H Gene

Evolution for MIR378H Gene

ENSEMBL:
Gene Tree for MIR378H (if available)
TreeFam:
Gene Tree for MIR378H (if available)

No data available for Orthologs for MIR378H Gene

Paralogs for MIR378H Gene

No data available for Paralogs for MIR378H Gene

Variants for MIR378H Gene

Sequence variations from dbSNP and Humsavar for MIR378H Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1002515682 -- 154,829,036(+) G/A upstream_transcript_variant
rs1004668166 -- 154,829,045(+) A/G upstream_transcript_variant
rs1004822971 -- 154,829,656(+) T/A downstream_transcript_variant
rs1005019462 -- 154,829,342(+) A/T upstream_transcript_variant
rs1006286886 -- 154,828,054(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR378H Gene

Variant ID Type Subtype PubMed ID
nsv830521 CNV gain 17160897

Additional Variant Information for MIR378H Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR378H

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378H Gene

Disorders for MIR378H Gene

Additional Disease Information for MIR378H

No disorders were found for MIR378H Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378H Gene

Publications for MIR378H Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR378H Gene

Sources for MIR378H Gene

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