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Aliases for MIR378C Gene

Subcategory (RNA class) for MIR378C Gene


Quality Score for this RNA gene is


Aliases for MIR378C Gene

  • MicroRNA 378c 2 3 5
  • Hsa-Mir-378c 3
  • Mir-378c 3

External Ids for MIR378C Gene

Previous GeneCards Identifiers for MIR378C Gene

  • GC10U901430
  • GC10M132760

Summaries for MIR378C Gene

Entrez Gene Summary for MIR378C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR378C Gene

MIR378C (MicroRNA 378c) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR378C Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR378C Gene

Genomics for MIR378C Gene

GeneHancer (GH) Regulatory Elements for MIR378C Gene

Promoters and enhancers for MIR378C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I130933 Enhancer 0.7 ENCODE 0.3 +26.9 26895 4.1 CTCF MXI1 USF1 JUN MAX RFX5 SMC3 RCOR1 CBFA2T2 FOS MIR378C LOC105378562
GH10I131048 Enhancer 0.6 ENCODE 0.2 -86.5 -86474 1.3 SIN3A REST ZIC2 ETS1 SP1 POLR2A CTBP2 POU5F1 EZH2 PIR59984 MIR378C
GH10I131001 Enhancer 0.3 ENCODE 0.3 -39.8 -39802 1 MAX MIR378C PIR59984
GH10I131088 Enhancer 0.8 FANTOM5 0.1 -126.1 -126062 0.1 CTCF ATF1 ETV1 ZBTB40 CTBP1 DIDO1 PHF20 ATF7 CREM L3MBTL2 PIR59984 MIR378C
GH10I131086 Enhancer 0.6 ENCODE 0.1 -123.6 -123625 0.2 SOX5 SOX13 GATAD2A TFAP4 ESRRA FOXA2 FOXA3 NR2F1 RARA NR2F6 PIR59984 MIR378C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR378C on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR378C Gene

Genomic Locations for MIR378C Gene
81 bases
Minus strand

Genomic View for MIR378C Gene

Genes around MIR378C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR378C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR378C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR378C Gene

Proteins for MIR378C Gene

Post-translational modifications for MIR378C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR378C Gene

Domains & Families for MIR378C Gene

Gene Families for MIR378C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR378C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR378C Gene

Function for MIR378C Gene

Phenotypes From GWAS Catalog for MIR378C Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR378C Gene

Localization for MIR378C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR378C Gene

Pathways & Interactions for MIR378C Gene

SuperPathways for MIR378C Gene

No Data Available

Interacting Proteins for MIR378C Gene

Gene Ontology (GO) - Biological Process for MIR378C Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR378C Gene

Drugs & Compounds for MIR378C Gene

No Compound Related Data Available

Transcripts for MIR378C Gene

mRNA/cDNA for MIR378C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR378C Gene

No ASD Table

Relevant External Links for MIR378C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR378C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR378C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR378C Gene:

genes like me logo Genes that share expression patterns with MIR378C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR378C Gene

Orthologs for MIR378C Gene

Evolution for MIR378C Gene

Gene Tree for MIR378C (if available)
Gene Tree for MIR378C (if available)

No data available for Orthologs for MIR378C Gene

Paralogs for MIR378C Gene

No data available for Paralogs for MIR378C Gene

Variants for MIR378C Gene

Sequence variations from dbSNP and Humsavar for MIR378C Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1001460526 -- 130,964,512(-) C/T upstream_transcript_variant
rs1003474645 -- 130,962,319(-) G/A downstream_transcript_variant
rs1004033674 -- 130,963,361(-) A/G upstream_transcript_variant
rs1004853359 -- 130,963,662(-) C/T upstream_transcript_variant
rs1005407594 -- 130,962,775(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR378C Gene

Variant ID Type Subtype PubMed ID
nsv1048253 CNV gain 25217958
nsv1054934 CNV gain 25217958
nsv428242 CNV gain 18775914
nsv552322 CNV gain 21841781

Additional Variant Information for MIR378C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR378C Gene

Disorders for MIR378C Gene

Additional Disease Information for MIR378C

No disorders were found for MIR378C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR378C Gene

Publications for MIR378C Gene

  1. Increased Proangiogenic Activity of Mobilized CD34+ Progenitor Cells of Patients With Acute ST-Segment-Elevation Myocardial Infarction: Role of Differential MicroRNA-378 Expression. (PMID: 28062497) Templin C … Landmesser U (Arteriosclerosis, thrombosis, and vascular biology 2017) 3 58
  2. Decreased expression of miR-378 correlates with tumor invasiveness and poor prognosis of patients with glioma. (PMID: 26261592) Li B … Tao B (International journal of clinical and experimental pathology 2015) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR378C Gene

Sources for MIR378C Gene

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