microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3688-2 Gene

Data sources for MIR3688-2 Gene:

Subcategory (RNA class) for MIR3688-2 Gene

miRNA

Aliases for MIR3688-2 Gene

External Ids for MIR3688-2 Gene

Previous GeneCards Identifiers for MIR3688-2 Gene

  • GC04U901496
  • GC04M160051
  • GC04P160052

Summaries for MIR3688-2 Gene

Entrez Gene Summary for MIR3688-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3688-2 Gene

MIR3688-2 (MicroRNA 3688-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3688-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3688-2 Gene

Genomics for MIR3688-2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3688-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J159125 Enhancer 0.9 Ensembl ENCODE 250.7 +0.2 196 7.2 IKZF1 CUX1 FOXA2 ZEB2 ZNF316 ADNP NFE2 HDAC2 FOXA1 RAD51 MIR3688-1 MIR3688-2 RAPGEF2 C4orf45 NONHSAG039225.2 HSALNG0038193
GH04J159102 Promoter/Enhancer 1.9 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.3 -23.7 -23724 6.2 TBP ZBTB10 BCL11A SP1 FEZF1 CEBPA IKZF1 SMAD5 MBD2 ELF1 NONHSAG039225.2 C4orf45 C4orf46 ENSG00000271817 ETFDH RAPGEF2 lnc-C4orf45-4 MIR3688-2
GH04J159118 Enhancer 0.6 Ensembl 0.4 -11.0 -11004 2 CEBPA RXRA MYNN JUND HNF4A ZBTB33 FOXA1 CEBPG KDM1A ZNF18 C4orf45 MIR3688-2 NONHSAG039225.2 RAPGEF2
GH04J159126 Enhancer 0.3 Ensembl 0.7 -4.7 -4704 0.2 ZBTB33 CHAMP1 ETFDH MIR3688-2 NONHSAG039225.2 RAPGEF2
GH04J159109 Enhancer 0.6 Ensembl 0.4 -18.4 -18404 2.4 TAL1 STAT5A CEBPG TEAD4 RFX1 ATF4 MEIS2 ARID1B DPF2 ATF3 C4orf45 NONHSAG039225.2 RAPGEF2 MIR3688-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3688-2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3688-2 Gene

Latest Assembly
chr4:159,128,805-159,128,891
(GRCh38/hg38)
Size:
87 bases
Orientation:
Plus strand

Previous Assembly
chr4:160,049,957-160,050,043
(GRCh37/hg19 by Entrez Gene)
Size:
87 bases
Orientation:
Plus strand

Genomic View for MIR3688-2 Gene

Genes around MIR3688-2 on UCSC Golden Path with GeneCards custom track
MIR3688-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3688-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3688-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3688-2 Gene

Proteins for MIR3688-2 Gene

Post-translational modifications for MIR3688-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3688-2 Gene

Domains & Families for MIR3688-2 Gene

Gene Families for MIR3688-2 Gene

HGNC:
genes like me logo Genes that share domains with MIR3688-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3688-2 Gene

Function for MIR3688-2 Gene

Phenotypes From GWAS Catalog for MIR3688-2 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3688-2 Gene

Localization for MIR3688-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3688-2 Gene

Pathways & Interactions for MIR3688-2 Gene

PathCards logo

SuperPathways for MIR3688-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3688-2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3688-2 Gene

Drugs & Compounds for MIR3688-2 Gene

No Compound Related Data Available

Transcripts for MIR3688-2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3688-2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C973_9606 precursor_RNA 87 4

RefSeq: NR_039963,

Ensembl: ENST00000636963 (view in UCSC) ,

miRBase: MI0017447,

ENA: LM611425.1:1..87:precursor_RNA,

URS000032B492_9606 miRNA 22 3

RefSeq: NR_037459, NR_039963,

miRBase: MIMAT0018116,

ENA: FR772804.1:1..22:ncRNA, FR772806.1:1..22:ncRNA, LM382162.1:1..22:ncRNA, LM611197.1:60..81:ncRNA, LM611425.1:57..78:ncRNA,

URS000025CFB9_9606 miRNA 21 3

RefSeq: NR_037459, NR_039963,

miRBase: MIMAT0019223,

ENA: FR772805.1:1..21:ncRNA, FR772807.1:1..21:ncRNA, LM611197.1:15..35:ncRNA, LM611425.1:12..32:ncRNA,

MIR3688-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3688-2 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3688-2 Gene

No ASD Table

Relevant External Links for MIR3688-2 Gene

GeneLoc Exon Structure for
MIR3688-2

Expression for MIR3688-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3688-2 Gene

genes like me logo Genes that share expression patterns with MIR3688-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3688-2 Gene

Orthologs for MIR3688-2 Gene

Evolution for MIR3688-2 Gene

ENSEMBL:
Gene Tree for MIR3688-2 (if available)
TreeFam:
Gene Tree for MIR3688-2 (if available)

No data available for Orthologs for MIR3688-2 Gene

Paralogs for MIR3688-2 Gene

No data available for Paralogs for MIR3688-2 Gene

Variants for MIR3688-2 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3688-2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3688-2 Gene

Variant ID Type Subtype PubMed ID
nsv4572 CNV insertion 18451855

Additional Variant Information for MIR3688-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3688-2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3688-2 Gene

Disorders for MIR3688-2 Gene

Additional Disease Information for MIR3688-2

No disorders were found for MIR3688-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3688-2 Gene

Publications for MIR3688-2 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

No data available for Mastermind for MIR3688-2 Gene

Products for MIR3688-2 Gene

Sources for MIR3688-2 Gene