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Aliases for MIR3681 Gene

Subcategory (RNA class) for MIR3681 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3681 Gene

  • MicroRNA 3681 2 3 5
  • Hsa-Mir-3681 3

External Ids for MIR3681 Gene

Previous GeneCards Identifiers for MIR3681 Gene

  • GC02U902252
  • GC02P012342

Summaries for MIR3681 Gene

Entrez Gene Summary for MIR3681 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3681 Gene

MIR3681 (MicroRNA 3681) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3681 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3681 Gene

Genomics for MIR3681 Gene

GeneHancer (GH) Regulatory Elements for MIR3681 Gene

Promoters and enhancers for MIR3681 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I012201 Enhancer 0.6 ENCODE 0.8 +3.5 3479 1.8 SOX6 BHLHE40 NRF1 GABPA MITF CC2D1A FOSL1 HDAC2 IKZF1 HMBOX1 MIR3681 GC02P012326 MIR3681HG
GH02I012276 Enhancer 1.5 FANTOM5 ENCODE dbSUPER 0.2 +78.4 78418 2.4 SMAD1 ATF1 ARNT TCF12 POLR2B ZNF766 GATA2 E2F8 ATF7 CAVIN1 TRIB2 GC02P012326 MIR3681 MIR3681HG
GH02I012192 Enhancer 0.7 FANTOM5 Ensembl 0.4 -6.1 -6051 0.6 JUN GABPB1 GABPA LOC105373432 LPIN1 MIR3681 MIR3681HG
GH02I012287 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.2 +88.3 88317 0.9 HDAC1 PKNOX1 ATF1 NFRKB NCOA2 ZNF766 CEBPB NCOA1 ZEB2 SMARCA4 GC02P012326 MIR3681 MIR3681HG
GH02I012262 Enhancer 0.9 FANTOM5 Ensembl ENCODE 0.2 +63.8 63771 1 MEIS2 PKNOX1 RFX1 ZNF83 TRIB2 MIR3681 GC02P012326 MIR3681HG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3681 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3681 Gene

Genomic Locations for MIR3681 Gene
chr2:12,199,130-12,199,201
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr2:12,339,256-12,339,327
(GRCh37/hg19)

Genomic View for MIR3681 Gene

Genes around MIR3681 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3681 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3681 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3681 Gene

Proteins for MIR3681 Gene

Post-translational modifications for MIR3681 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3681 Gene

Domains & Families for MIR3681 Gene

Gene Families for MIR3681 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3681: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3681 Gene

Function for MIR3681 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3681 Gene

Localization for MIR3681 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3681 Gene

Pathways & Interactions for MIR3681 Gene

SuperPathways for MIR3681 Gene

No Data Available

Interacting Proteins for MIR3681 Gene

Gene Ontology (GO) - Biological Process for MIR3681 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3681 Gene

Drugs & Compounds for MIR3681 Gene

No Compound Related Data Available

Transcripts for MIR3681 Gene

mRNA/cDNA for MIR3681 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3681 Gene

No ASD Table

Relevant External Links for MIR3681 Gene

GeneLoc Exon Structure for
MIR3681
ECgene alternative splicing isoforms for
MIR3681

Expression for MIR3681 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3681 Gene:

MIR3681
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3681 Gene

Orthologs for MIR3681 Gene

Evolution for MIR3681 Gene

ENSEMBL:
Gene Tree for MIR3681 (if available)
TreeFam:
Gene Tree for MIR3681 (if available)

No data available for Orthologs for MIR3681 Gene

Paralogs for MIR3681 Gene

No data available for Paralogs for MIR3681 Gene

Variants for MIR3681 Gene

Sequence variations from dbSNP and Humsavar for MIR3681 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000099950 -- 12,198,480(+) T/C upstream_transcript_variant
rs1001202357 -- 12,197,840(+) A/G upstream_transcript_variant
rs1001256130 -- 12,198,075(+) G/A upstream_transcript_variant
rs1002971737 -- 12,198,693(+) A/G upstream_transcript_variant
rs1004485923 -- 12,198,978(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3681 Gene

Variant ID Type Subtype PubMed ID
nsv1001333 CNV loss 25217958

Additional Variant Information for MIR3681 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3681

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3681 Gene

Disorders for MIR3681 Gene

Additional Disease Information for MIR3681

No disorders were found for MIR3681 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3681 Gene

Publications for MIR3681 Gene

  1. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C … Bhattacharya A (BMC genomics 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3681 Gene

Sources for MIR3681 Gene

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