microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3680-2 Gene

Subcategory (RNA class) for MIR3680-2 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR3680-2 Gene

  • MicroRNA 3680-2 2 3 5
  • Hsa-Mir-3680-2 2 3
  • MIR3680-2 2 5
  • MIMAT0018106 50
  • MIMAT0018107 50
  • MIR3680-1 2
  • MI0019113 50
  • MI0016081 50

External Ids for MIR3680-2 Gene

Previous GeneCards Identifiers for MIR3680-2 Gene

  • GC16U901353
  • GC16M029613
  • GC16M029600
  • GC16M029617

Summaries for MIR3680-2 Gene

Entrez Gene Summary for MIR3680-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3680-2 Gene

MIR3680-2 (MicroRNA 3680-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3680-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3680-2 Gene

Genomics for MIR3680-2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3680-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J029597 Promoter 0.6 Ensembl 600.7 +1.5 1464 0.8 ESR1 ZBTB17 NR2F6 ZNF362 SP7 ENSG00000279583 LOC105371168 MIR3680-2 piR-37516-002 CA5AP1 SMG1P2 SPN NPIPB12
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3680-2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3680-2 Gene

Genomic Locations for MIR3680-2 Gene
chr16:29,599,179-29,599,265
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand
chr16:29,610,500-29,610,586
(GRCh37/hg19)
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR3680-2 Gene

Genes around MIR3680-2 on UCSC Golden Path with GeneCards custom track
MIR3680-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3680-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3680-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3680-2 Gene

Proteins for MIR3680-2 Gene

Post-translational modifications for MIR3680-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3680-2 Gene

Domains & Families for MIR3680-2 Gene

Gene Families for MIR3680-2 Gene

genes like me logo Genes that share domains with MIR3680-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3680-2 Gene

Function for MIR3680-2 Gene

Phenotypes From GWAS Catalog for MIR3680-2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3680-2 Gene

Localization for MIR3680-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3680-2 Gene

Pathways & Interactions for MIR3680-2 Gene

PathCards logo

SuperPathways for MIR3680-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3680-2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3680-2 Gene

Drugs & Compounds for MIR3680-2 Gene

No Compound Related Data Available

Transcripts for MIR3680-2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3680-2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CE98_9606 precursor_RNA 87 4

HGNC: 38989, 43472,

RefSeq: NR_037451, NR_049833,

Ensembl: ENST00000578247 (view in UCSC) , ENST00000581433 (view in UCSC) ,

miRBase: MI0016081, MI0019113,

URS000075F058_9606 miRNA 23 2

RefSeq: NR_037451, NR_049833,

miRBase: MIMAT0018107,

URS00005EAC45_9606 miRNA 22 2

RefSeq: NR_037451, NR_049833,

miRBase: MIMAT0018106,

MIR3680-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3680-2 Gene

No ASD Table

Relevant External Links for MIR3680-2 Gene

GeneLoc Exon Structure for
MIR3680-2

No data available for mRNA/cDNA for MIR3680-2 Gene

Expression for MIR3680-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3680-2 Gene

genes like me logo Genes that share expression patterns with MIR3680-2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3680-2 Gene

Orthologs for MIR3680-2 Gene

Evolution for MIR3680-2 Gene

ENSEMBL:
Gene Tree for MIR3680-2 (if available)
TreeFam:
Gene Tree for MIR3680-2 (if available)

No data available for Orthologs for MIR3680-2 Gene

Paralogs for MIR3680-2 Gene

No data available for Paralogs for MIR3680-2 Gene

Variants for MIR3680-2 Gene

Additional dbSNP identifiers (rs#s) for MIR3680-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3680-2 Gene

Variant ID Type Subtype PubMed ID
dgv1316n106 CNV duplication 24896259
dgv2800n100 CNV gain 25217958
dgv2801n100 CNV loss 25217958
esv2421840 CNV deletion 20811451
esv25717 CNV gain+loss 19812545
esv2758636 CNV gain+loss 17122850
esv2758641 CNV gain 17122850
esv2762010 CNV gain+loss 21179565
esv2763135 CNV gain 21179565
esv29892 CNV gain 19812545
esv32773 CNV loss 17666407
esv33799 CNV loss 17666407
esv34235 CNV gain 17911159
esv3584705 CNV loss 24956385
nsv1056249 CNV gain 25217958
nsv1076422 CNV duplication 25765185
nsv1152437 CNV duplication 26484159
nsv1160372 CNV duplication 26073780
nsv428322 CNV gain 18775914
nsv433437 CNV gain 18776910
nsv433438 CNV gain 18776910
nsv442716 CNV gain 18776908
nsv509606 CNV insertion 20534489
nsv827584 CNV gain 20364138
nsv9397 CNV gain+loss 18304495
nsv9429 CNV loss 18304495
nsv978108 CNV duplication 23825009
nsv978128 CNV duplication 23825009

Additional Variant Information for MIR3680-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3680-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3680-2 Gene

Disorders for MIR3680-2 Gene

Additional Disease Information for MIR3680-2

No disorders were found for MIR3680-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3680-2 Gene

Publications for MIR3680-2 Gene

  1. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C … Bhattacharya A (BMC genomics 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3680-2 Gene

Sources for MIR3680-2 Gene