microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3679 Gene

Data sources for MIR3679 Gene:

Subcategory (RNA class) for MIR3679 Gene

miRNA

Aliases for MIR3679 Gene

External Ids for MIR3679 Gene

Previous GeneCards Identifiers for MIR3679 Gene

  • GC02U902266
  • GC02P134887

Summaries for MIR3679 Gene

Entrez Gene Summary for MIR3679 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3679 Gene

MIR3679 (MicroRNA 3679) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3679 include Moyamoya Disease 1.

Additional gene information for MIR3679 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3679 Gene

Genomics for MIR3679 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3679 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J134127 Enhancer 0.7 ENCODE dbSUPER 250.7 +0.6 560 0.2 EBF1 ZNF316 CBFB BHLHE40 MTA3 POLR2A MAFK TCF12 RUNX3 EMSY MIR3679 MGAT5 piR-52679 lnc-TMEM163-4 TMEM163
GH02J134117 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -5.0 -5000 8.3 TBP SP1 ZBTB10 MXD4 BCL11A MNT DEK IKZF1 SMAD5 IRF2 MGAT5 MIR3679 lnc-TMEM163-4 TMEM163
GH02J134132 Enhancer 1.1 ENCODE dbSUPER 0.4 +5.5 5540 0.2 CEBPA MNT HES1 BHLHE40 HOMEZ KDM6A ARNT REST ZNF395 FOXA2 MIR3679 piR-52679 MGAT5 lnc-TMEM163-4 TMEM163
GH02J134131 Enhancer 0.5 dbSUPER 0.7 +4.8 4775 0.6 ZNF395 ZNF189 EP400 ZBTB40 TFAP4 ZNF384 ZNF512 ZNF644 MIR3679 piR-52679 MGAT5 lnc-TMEM163-4 TMEM163
GH02J134136 Enhancer 0.8 ENCODE CraniofacialAtlas dbSUPER 0.4 +10.4 10378 2.2 SPI1 CTCF EP300 ATF3 CBFA2T3 piR-52679 MIR3679 MGAT5 lnc-TMEM163-4 TMEM163
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3679 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3679 Gene

Latest Assembly
chr2:134,127,125-134,127,192
(GRCh38/hg38)
Size:
68 bases
Orientation:
Plus strand

Previous Assembly
chr2:134,884,696-134,884,763
(GRCh37/hg19 by Entrez Gene)
Size:
68 bases
Orientation:
Plus strand

chr2:134,884,696-134,884,763
(GRCh37/hg19 by Ensembl)
Size:
68 bases
Orientation:
Plus strand

Genomic View for MIR3679 Gene

Genes around MIR3679 on UCSC Golden Path with GeneCards custom track
MIR3679 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3679 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3679 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3679 Gene

Proteins for MIR3679 Gene

Post-translational modifications for MIR3679 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3679 Gene

Domains & Families for MIR3679 Gene

Gene Families for MIR3679 Gene

HGNC:
genes like me logo Genes that share domains with MIR3679: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3679 Gene

Function for MIR3679 Gene

Phenotypes From GWAS Catalog for MIR3679 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3679 Gene

Localization for MIR3679 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3679 gene
Compartment Confidence
extracellular 1
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for MIR3679 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 31926946
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR3679: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR3679 Gene

Pathways & Interactions for MIR3679 Gene

PathCards logo

SuperPathways for MIR3679 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3679 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3679 Gene

Drugs & Compounds for MIR3679 Gene

No Compound Related Data Available

Transcripts for MIR3679 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3679 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00000D0BB4_9606 miRNA 23 5

RefSeq: NR_037450,

LncBase: hsa-miR-3679-5p,

miRBase: MIMAT0018104,

TarBase: hsa-miR-3679-5p,

ENA: FR772802.1:1..23:ncRNA, LM382159.1:1..23:ncRNA, LM611194.1:6..28:ncRNA,

URS000075AC34_9606 precursor_RNA 68 4

RefSeq: NR_037450,

Ensembl: ENST00000581102 (view in UCSC) ,

miRBase: MI0016080,

ENA: LM611194.1:1..68:precursor_RNA,

URS00003E3F4E_9606 miRNA 22 3

RefSeq: NR_037450,

miRBase: MIMAT0018105,

ENA: FR772801.1:1..22:ncRNA, LM611194.1:44..65:ncRNA,

MIR3679 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3679 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3679 Gene

No ASD Table

Relevant External Links for MIR3679 Gene

GeneLoc Exon Structure for
MIR3679

Expression for MIR3679 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3679 Gene

Orthologs for MIR3679 Gene

Evolution for MIR3679 Gene

ENSEMBL:
Gene Tree for MIR3679 (if available)
TreeFam:
Gene Tree for MIR3679 (if available)

No data available for Orthologs for MIR3679 Gene

Paralogs for MIR3679 Gene

No data available for Paralogs for MIR3679 Gene

Variants for MIR3679 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3679 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3679 Gene

Variant ID Type Subtype PubMed ID
dgv7088n54 CNV loss 21841781
nsv1008965 CNV loss 25217958

Additional Variant Information for MIR3679 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3679

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3679 Gene

Disorders for MIR3679 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3679 Gene - From: COP

Disorder Aliases PubMed IDs
moyamoya disease 1
  • mymy1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3679

genes like me logo Genes that share disorders with MIR3679: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3679 Gene

Publications for MIR3679 Gene

  1. Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C. (PMID: 31926946) Hu W … Zhang R (Experimental cell research 2020) 3
  2. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. (PMID: 32125007) Higashijima Y … Kanki Y (The EMBO journal 2020) 3
  3. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  4. Salivary microRNAs show potential as a noninvasive biomarker for detecting resectable pancreatic cancer. (PMID: 25538087) Xie Z … Li Z (Cancer prevention research (Philadelphia, Pa.) 2015) 3
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3

Products for MIR3679 Gene

Sources for MIR3679 Gene