microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3678 Gene

Data sources for MIR3678 Gene:

Subcategory (RNA class) for MIR3678 Gene

miRNA

Aliases for MIR3678 Gene

External Ids for MIR3678 Gene

Previous GeneCards Identifiers for MIR3678 Gene

  • GC17U901543
  • GC17P073405

Summaries for MIR3678 Gene

Entrez Gene Summary for MIR3678 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3678 Gene

MIR3678 (MicroRNA 3678) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3678 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3678 Gene

Genomics for MIR3678 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3678 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J075401 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -1.7 -1659 5.2 CHD2 TBP ZBTB10 SP1 MXD4 ZNF217 MNT DEK IKZF1 BRCA1 GRB2 MIR3678 lnc-CASKIN2-5 NUP85 UNK GGA3 ENSG00000266980 CDK3 NAT9 ENSG00000267342
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3678 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3678 Gene

Latest Assembly
chr17:75,406,069-75,406,162
(GRCh38/hg38)
Size:
94 bases
Orientation:
Plus strand

Previous Assembly
chr17:73,402,150-73,402,243
(GRCh37/hg19 by Entrez Gene)
Size:
94 bases
Orientation:
Plus strand

chr17:73,402,150-73,402,243
(GRCh37/hg19 by Ensembl)
Size:
94 bases
Orientation:
Plus strand

Genomic View for MIR3678 Gene

Genes around MIR3678 on UCSC Golden Path with GeneCards custom track
MIR3678 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3678 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3678 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3678 Gene

Proteins for MIR3678 Gene

Post-translational modifications for MIR3678 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3678 Gene

Domains & Families for MIR3678 Gene

Gene Families for MIR3678 Gene

HGNC:
genes like me logo Genes that share domains with MIR3678: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3678 Gene

Function for MIR3678 Gene

Phenotypes From GWAS Catalog for MIR3678 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3678 Gene

Localization for MIR3678 Gene

Gene Ontology (GO) - Cellular Components for MIR3678 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR3678: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3678 Gene

Pathways & Interactions for MIR3678 Gene

PathCards logo

SuperPathways for MIR3678 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3678 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3678 Gene

Drugs & Compounds for MIR3678 Gene

No Compound Related Data Available

Transcripts for MIR3678 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3678 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DF0D_9606 precursor_RNA 94 4

RefSeq: NR_037449,

Ensembl: ENST00000578455 (view in UCSC) ,

miRBase: MI0016079,

ENA: LM611193.1:1..94:precursor_RNA,

URS000075BC79_9606 miRNA 22 3

RefSeq: NR_037449,

miRBase: MIMAT0018103,

ENA: LM382158.1:1..22:ncRNA, LM611193.1:69..90:ncRNA,

URS000075A9CF_9606 miRNA 20 3

RefSeq: NR_037449,

miRBase: MIMAT0018102,

ENA: LM611193.1:9..28:ncRNA,

MIR3678 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3678 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3678 Gene

No ASD Table

Relevant External Links for MIR3678 Gene

GeneLoc Exon Structure for
MIR3678

Expression for MIR3678 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3678 Gene

genes like me logo Genes that share expression patterns with MIR3678: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3678 Gene

Orthologs for MIR3678 Gene

Evolution for MIR3678 Gene

ENSEMBL:
Gene Tree for MIR3678 (if available)
TreeFam:
Gene Tree for MIR3678 (if available)

No data available for Orthologs for MIR3678 Gene

Paralogs for MIR3678 Gene

No data available for Paralogs for MIR3678 Gene

Variants for MIR3678 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3678 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3678 Gene

Variant ID Type Subtype PubMed ID
nsv576027 CNV gain 21841781
nsv833541 CNV loss 17160897

Additional Variant Information for MIR3678 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3678

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3678 Gene

Disorders for MIR3678 Gene

Additional Disease Information for MIR3678

No disorders were found for MIR3678 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3678 Gene

Publications for MIR3678 Gene

  1. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. (PMID: 20459673) Vaz C … Bhattacharya A (BMC genomics 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3678 Gene

Sources for MIR3678 Gene