microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3665 Gene

Data sources for MIR3665 Gene:

RNA type for MIR3665 Gene

miRNA

Aliases for MIR3665 Gene

External Ids for MIR3665 Gene

Previous GeneCards Identifiers for MIR3665 Gene

  • GC13U900812
  • GC13M078274

Summaries for MIR3665 Gene

Entrez Gene Summary for MIR3665 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3665 Gene

MIR3665 (MicroRNA 3665) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3665 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3665 Gene

Genomics for MIR3665 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3665 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J077696 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 250.7 -0.6 -585 5.8 SP1 ZNF600 POLR2A ZNF10 YY1 ZNF592 SIN3A TARDBP FEZF1 FOXA2 HSALNG0098068 MIR3665 SLAIN1 RPL31P54 piR-61532-090 lnc-EDNRB-4 HSALNG0098066 EDNRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3665 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3665 Gene

Latest Assembly
chr13:77,698,012-77,698,116
(GRCh38/hg38)
Size:
105 bases
Orientation:
Minus strand

Previous Assembly
chr13:78,272,147-78,272,251
(GRCh37/hg19 by Entrez Gene)
Size:
105 bases
Orientation:
Minus strand

chr13:78,272,147-78,272,251
(GRCh37/hg19 by Ensembl)
Size:
105 bases
Orientation:
Minus strand

Genomic View for MIR3665 Gene

Genes around MIR3665 on UCSC Golden Path with GeneCards custom track
MIR3665 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3665 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3665 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3665 Gene

Proteins for MIR3665 Gene

Post-translational modifications for MIR3665 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3665 Gene

Domains & Families for MIR3665 Gene

Gene Families for MIR3665 Gene

HGNC:
genes like me logo Genes that share domains with MIR3665: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3665 Gene

Function for MIR3665 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3665 Gene

Localization for MIR3665 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3665 Gene

Pathways & Interactions for MIR3665 Gene

PathCards logo

SuperPathways for MIR3665 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3665 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3665 Gene

Drugs & Compounds for MIR3665 Gene

No Compound Related Data Available

Transcripts for MIR3665 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3665 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075E1E9_9606 pre_miRNA 105 3

RefSeq: NR_037438,

Ensembl: ENST00000578708 (view in UCSC) ,

miRBase: MI0016066,

URS000075AFFF_9606 miRNA 18 2

RefSeq: NR_037438,

miRBase: MIMAT0018087,

MIR3665 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3665 Gene

No ASD Table

Relevant External Links for MIR3665 Gene

GeneLoc Exon Structure for
MIR3665

No data available for mRNA/cDNA for MIR3665 Gene

Expression for MIR3665 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3665 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3665 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x10.3), Brain - Substantia nigra (x5.2), and Brain - Hippocampus (x4.2).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3665

genes like me logo Genes that share expression patterns with MIR3665: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3665 Gene

Orthologs for MIR3665 Gene

Evolution for MIR3665 Gene

ENSEMBL:
Gene Tree for MIR3665 (if available)
TreeFam:
Gene Tree for MIR3665 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3665

No data available for Orthologs for MIR3665 Gene

Paralogs for MIR3665 Gene

No data available for Paralogs for MIR3665 Gene

Variants for MIR3665 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3665 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3665 Gene

Variant ID Type Subtype PubMed ID
dgv3262n54 CNV gain 21841781
dgv3263n54 CNV loss 21841781
esv23084 CNV loss 19812545
nsv1070597 CNV deletion 25765185
nsv1136173 CNV deletion 24896259
nsv562376 CNV loss 21841781
nsv562377 CNV gain 21841781
nsv562387 CNV loss 21841781
nsv562388 CNV loss 21841781
nsv951899 CNV duplication 24416366

Additional Variant Information for MIR3665 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3665
Leiden Open Variation Database (LOVD)
MIR3665

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3665 Gene

Disorders for MIR3665 Gene

Additional Disease Information for MIR3665

No disorders were found for MIR3665 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3665 Gene

Publications for MIR3665 Gene

  1. Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment. (PMID: 20559549) Smith B … Sikorska M (PloS one 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
  3. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. (PMID: 15735639) Xie X … Kellis M (Nature 2005) 3

Products for MIR3665 Gene

Sources for MIR3665 Gene