microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3664 Gene

Data sources for MIR3664 Gene:

RNA type for MIR3664 Gene

miRNA

Aliases for MIR3664 Gene

External Ids for MIR3664 Gene

Previous GeneCards Identifiers for MIR3664 Gene

  • GC11U901776
  • GC11M070721

Summaries for MIR3664 Gene

Entrez Gene Summary for MIR3664 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3664 Gene

MIR3664 (MicroRNA 3664) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3664 include Spinal Cord Glioma.

Additional gene information for MIR3664 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3664 Gene

Genomics for MIR3664 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3664 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J070872 Enhancer 0.9 Ensembl ENCODE CraniofacialAtlas 250.7 -0.5 -533 2.2 ETS1 CTBP1 RFX1 TRIM24 POLR2A GATAD2A MTA2 CEBPB MIR3664 PPFIA1 HSALNG0085447 SHANK2 CTTN
GH11J070876 Enhancer 0.2 Ensembl 0.7 -4.4 -4433 0.4 MIR3664 HSALNG0085447 SHANK2 CTTN
GH11J070877 Enhancer 0.2 Ensembl 0.4 -5.8 -5833 0.8 KRTAP5-9 MIR3664 HSALNG0085447 SHANK2 CTTN
GH11J070883 Enhancer 0.2 ENCODE 0.4 -11.9 -11939 0.9 ENSG00000286708 HSALNG0085447 SHANK2 MIR3664 CTTN
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3664 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3664 Gene

Latest Assembly
chr11:70,872,270-70,872,368
(GRCh38/hg38)
Size:
99 bases
Orientation:
Minus strand

Previous Assembly
chr11:70,718,375-70,718,473
(GRCh37/hg19 by Entrez Gene)
Size:
99 bases
Orientation:
Minus strand

chr11:70,718,375-70,718,473
(GRCh37/hg19 by Ensembl)
Size:
99 bases
Orientation:
Minus strand

Genomic View for MIR3664 Gene

Genes around MIR3664 on UCSC Golden Path with GeneCards custom track
MIR3664 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3664 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3664 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3664 Gene

Proteins for MIR3664 Gene

Post-translational modifications for MIR3664 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3664 Gene

Domains & Families for MIR3664 Gene

Gene Families for MIR3664 Gene

HGNC:
genes like me logo Genes that share domains with MIR3664: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3664 Gene

Function for MIR3664 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3664 Gene

Localization for MIR3664 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3664 Gene

Pathways & Interactions for MIR3664 Gene

PathCards logo

SuperPathways for MIR3664 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3664 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3664 Gene

Drugs & Compounds for MIR3664 Gene

No Compound Related Data Available

Transcripts for MIR3664 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3664 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075991E_9606 precursor_RNA 99 4

RefSeq: NR_037437,

Ensembl: ENST00000579074 (view in UCSC) ,

miRBase: MI0016065,

ENA: LM611190.1:1..99:precursor_RNA,

URS000043C1C3_9606 miRNA 22 3

RefSeq: NR_037437,

miRBase: MIMAT0019220,

ENA: FR772797.1:1..22:ncRNA, LM382501.1:1..22:ncRNA, LM611190.1:59..80:ncRNA,

URS000075CCEC_9606 miRNA 22 3

RefSeq: NR_037437,

miRBase: MIMAT0018086,

ENA: LM611190.1:21..42:ncRNA,

URS00003B40D2_9606 miRNA 21 1

ENA: FR772798.1:1..21:ncRNA,

MIR3664 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3664 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3664 Gene

No ASD Table

Relevant External Links for MIR3664 Gene

GeneLoc Exon Structure for
MIR3664

Expression for MIR3664 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3664 Gene

genes like me logo Genes that share expression patterns with MIR3664: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3664 Gene

Orthologs for MIR3664 Gene

Evolution for MIR3664 Gene

ENSEMBL:
Gene Tree for MIR3664 (if available)
TreeFam:
Gene Tree for MIR3664 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3664

No data available for Orthologs for MIR3664 Gene

Paralogs for MIR3664 Gene

No data available for Paralogs for MIR3664 Gene

Variants for MIR3664 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3664 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3664 Gene

Variant ID Type Subtype PubMed ID
esv993927 CNV deletion 20482838
nsv381 CNV insertion 18451855
nsv555399 CNV loss 21841781

Additional Variant Information for MIR3664 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3664
Leiden Open Variation Database (LOVD)
MIR3664

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3664 Gene

Disorders for MIR3664 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3664 Gene - From: GCD

Disorder Aliases PubMed IDs
spinal cord glioma
  • glial neoplasm spinal cord
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3664

genes like me logo Genes that share disorders with MIR3664: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3664 Gene

Publications for MIR3664 Gene

  1. Comparison of Alterations in miRNA Expression in Matched Tissue and Blood Samples during Spinal Cord Glioma Progression. (PMID: 31235820) An T … Jiang GJ (Scientific reports 2019) 3
  2. miR‑3664‑5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF‑κB signaling pathway through targeting MTDH. (PMID: 30628643) Jiao Y … Tang L (International journal of oncology 2019) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  5. Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. (PMID: 20532037) Hansen TB … Kjems J (PloS one 2010) 3

Products for MIR3664 Gene

Sources for MIR3664 Gene