microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3658 Gene

Subcategory (RNA class) for MIR3658 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR3658 Gene

  • MicroRNA 3658 2 3 5
  • Hsa-Mir-3658 2 3
  • MIR3658 2 5
  • MIMAT0018078 50
  • MI0016058 50

External Ids for MIR3658 Gene

Previous GeneCards Identifiers for MIR3658 Gene

  • GC01U903155
  • GC01P165882
  • GC01P165828

Summaries for MIR3658 Gene

Entrez Gene Summary for MIR3658 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3658 Gene

MIR3658 (MicroRNA 3658) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3658 include Pediatric Hepatocellular Carcinoma. Among its related pathways are Metabolism of nucleotides and Fluoropyrimidine Activity.

Additional gene information for MIR3658 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3658 Gene

Genomics for MIR3658 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3658 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J165902 Enhancer 0.6 ENCODE dbSUPER 0.7 -4.1 -4096 2 ZBTB17 CREM ATF1 UCK2 ENSG00000236364 TMCO1 TMCO1-AS1 FAM78B-AS1 MIR3658 lnc-MGST3-5 FAM78B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3658 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3658 Gene

Genomic Locations for MIR3658 Gene
chr1:165,907,921-165,907,976
(GRCh38/hg38)
Size:
56 bases
Orientation:
Plus strand
chr1:165,877,158-165,877,213
(GRCh37/hg19)
Size:
56 bases
Orientation:
Plus strand

Genomic View for MIR3658 Gene

Genes around MIR3658 on UCSC Golden Path with GeneCards custom track
MIR3658 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3658 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3658 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3658 Gene

Proteins for MIR3658 Gene

Post-translational modifications for MIR3658 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3658 Gene

Domains & Families for MIR3658 Gene

Gene Families for MIR3658 Gene

HGNC:
genes like me logo Genes that share domains with MIR3658: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3658 Gene

Function for MIR3658 Gene

Phenotypes From GWAS Catalog for MIR3658 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3658 Gene

Localization for MIR3658 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3658 Gene

Pathways & Interactions for MIR3658 Gene

genes like me logo Genes that share pathways with MIR3658: view

Pathways by source for MIR3658 Gene

1 BioSystems pathway for MIR3658 Gene

Gene Ontology (GO) - Biological Process for MIR3658 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3658 Gene

Drugs & Compounds for MIR3658 Gene

No Compound Related Data Available

Transcripts for MIR3658 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3658 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BCB3_9606 precursor_RNA 56 4

HGNC: 38963,

RefSeq: NR_037431,

Ensembl: ENST00000636291 (view in UCSC) ,

miRBase: MI0016058,

URS000075A6CE_9606 miRNA 22 2

RefSeq: NR_037431,

miRBase: MIMAT0018078,

MIR3658 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3658 Gene

No ASD Table

Relevant External Links for MIR3658 Gene

GeneLoc Exon Structure for
MIR3658

No data available for mRNA/cDNA for MIR3658 Gene

Expression for MIR3658 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3658 Gene

genes like me logo Genes that share expression patterns with MIR3658: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3658 Gene

Orthologs for MIR3658 Gene

Evolution for MIR3658 Gene

ENSEMBL:
Gene Tree for MIR3658 (if available)
TreeFam:
Gene Tree for MIR3658 (if available)

No data available for Orthologs for MIR3658 Gene

Paralogs for MIR3658 Gene

No data available for Paralogs for MIR3658 Gene

Variants for MIR3658 Gene

Additional dbSNP identifiers (rs#s) for MIR3658 Gene

Additional Variant Information for MIR3658 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3658

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3658 Gene

Disorders for MIR3658 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3658 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pediatric hepatocellular carcinoma
  • childhood hepatocellular carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3658

genes like me logo Genes that share disorders with MIR3658: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3658 Gene

Publications for MIR3658 Gene

  1. Hsa-miR-3658 Promotes Cell Proliferation, Migration and Invasion by Effecting LASS2 in Bladder Cancer. (PMID: 29739079) Luan T … Wang J (Clinical laboratory 2018) 3
  2. Upregulation of miR-3658 in bladder cancer and tumor progression. (PMID: 27820650) Chen YJ … Wang JS (Genetics and molecular research : GMR 2016) 3
  3. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3658 Gene

Sources for MIR3658 Gene