microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3657 Gene

Subcategory (RNA class) for MIR3657 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR3657 Gene

  • MicroRNA 3657 2 3 5
  • Hsa-Mir-3657 2 3
  • Hsa-MiR-3657 163 173
  • MIR3657 2 5
  • MIMAT0018077 50
  • MI0016057 50

External Ids for MIR3657 Gene

Previous GeneCards Identifiers for MIR3657 Gene

  • GC12U901522
  • GC12M112477

Summaries for MIR3657 Gene

Entrez Gene Summary for MIR3657 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3657 Gene

MIR3657 (MicroRNA 3657) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3657 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3657 Gene

Genomics for MIR3657 Gene

Genomic Locations for MIR3657 Gene

Genomic Locations for MIR3657 Gene
chr12:112,037,599-112,037,715
(GRCh38/hg38)
Size:
117 bases
Orientation:
Minus strand
chr12:112,475,403-112,475,519
(GRCh37/hg19)
Size:
117 bases
Orientation:
Minus strand

Genomic View for MIR3657 Gene

Genes around MIR3657 on UCSC Golden Path with GeneCards custom track
MIR3657 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3657 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3657 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3657 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR3657 Gene

Proteins for MIR3657 Gene

Post-translational modifications for MIR3657 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3657 Gene

Domains & Families for MIR3657 Gene

Gene Families for MIR3657 Gene

HGNC:
genes like me logo Genes that share domains with MIR3657: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3657 Gene

Function for MIR3657 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3657 Gene

Localization for MIR3657 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3657 gene
Compartment Confidence
endoplasmic reticulum 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3657 Gene

Pathways & Interactions for MIR3657 Gene

PathCards logo

SuperPathways for MIR3657 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3657 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3657 Gene

Drugs & Compounds for MIR3657 Gene

No Compound Related Data Available

Transcripts for MIR3657 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3657 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B6BC_9606 precursor_RNA 117 4

HGNC: 38906,

RefSeq: NR_037430,

Ensembl: ENST00000584818 (view in UCSC) ,

miRBase: MI0016057,

URS000075C59B_9606 miRNA 21 4

RefSeq: NR_037430,

LncBase: hsa-miR-3657,

miRBase: MIMAT0018077,

TarBase: hsa-miR-3657,

MIR3657 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3657 Gene

No ASD Table

Relevant External Links for MIR3657 Gene

GeneLoc Exon Structure for
MIR3657

No data available for mRNA/cDNA for MIR3657 Gene

Expression for MIR3657 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3657 Gene

genes like me logo Genes that share expression patterns with MIR3657: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3657 Gene

Orthologs for MIR3657 Gene

Evolution for MIR3657 Gene

ENSEMBL:
Gene Tree for MIR3657 (if available)
TreeFam:
Gene Tree for MIR3657 (if available)

No data available for Orthologs for MIR3657 Gene

Paralogs for MIR3657 Gene

No data available for Paralogs for MIR3657 Gene

Variants for MIR3657 Gene

Additional dbSNP identifiers (rs#s) for MIR3657 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3657 Gene

Variant ID Type Subtype PubMed ID
nsv52789 CNV deletion 16902084

Additional Variant Information for MIR3657 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3657

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3657 Gene

Disorders for MIR3657 Gene

Additional Disease Information for MIR3657

No disorders were found for MIR3657 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3657 Gene

Publications for MIR3657 Gene

  1. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3657 Gene

Sources for MIR3657 Gene