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Aliases for MIR3653 Gene

Subcategory (RNA class) for MIR3653 Gene

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Quality Score for this RNA gene is

4

Aliases for MIR3653 Gene

  • MicroRNA 3653 2 3 5
  • Hsa-Mir-3653 3
  • Mir-3653 3

External Ids for MIR3653 Gene

Previous GeneCards Identifiers for MIR3653 Gene

  • GC22U900730
  • GC22M029732

Summaries for MIR3653 Gene

Entrez Gene Summary for MIR3653 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3653 Gene

MIR3653 (MicroRNA 3653) is an RNA Gene, and is affiliated with the undefined RNA class.

fRNAdb sequence ontologies for MIR3653 Gene

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

Additional gene information for MIR3653 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3653 Gene

Genomics for MIR3653 Gene

GeneHancer (GH) Regulatory Elements for MIR3653 Gene

Promoters and enhancers for MIR3653 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I029332 Enhancer 0.2 dbSUPER 550.8 +0.1 105 1 MIR3653 SNORD125 GAS2L1 RHBDD3 AP1B1 RASL10A
GH22I029336 Enhancer 0.7 ENCODE dbSUPER 0.8 -4.0 -4024 1.8 HIC1 RXRA MAX HNF4A YY1 GAS2L1 MIR3653 LOC102723305 AP1B1
GH22I029381 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 0.2 -52.1 -52137 8.1 PKNOX1 SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 SLC30A9 AP1B1 RASL10A SNORD125 ZNRF3 GAS2L1 RHBDD3 LOC102723305 MIR3653
GH22I029341 Enhancer 1.1 ENCODE dbSUPER 0.4 -10.2 -10155 3.4 PKNOX1 FOXA2 NEUROD1 SIN3A FOS RXRA TSHZ1 ZNF518A ZSCAN16 GLIS1 RASL10A GAS2L1 ENSG00000237015 RHBDD3 MIR3653 LOC102723305 AP1B1
GH22I029368 Enhancer 1.1 FANTOM5 Ensembl ENCODE 0.3 -36.3 -36270 1.3 ZNF266 MAX ZIC2 FOSL1 PRDM10 FOS ZNF362 ZNF189 NRF1 HLF EWSR1 SF3A1 AP1B1 RASL10A SNORD125 TBC1D10A ENSG00000272858 THOC5 NEFH ZNRF3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3653 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3653 Gene

Genomic Locations for MIR3653 Gene
chr22:29,333,158-29,333,267
(GRCh38/hg38)
Size:
110 bases
Orientation:
Minus strand
chr22:29,729,147-29,729,256
(GRCh37/hg19)

Genomic View for MIR3653 Gene

Genes around MIR3653 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3653 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3653 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3653 Gene

ORGUL Member Location for MIR3653 Gene

ORGUL Member Location for MIR3653 gene

Proteins for MIR3653 Gene

Post-translational modifications for MIR3653 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3653 Gene

Domains & Families for MIR3653 Gene

Gene Families for MIR3653 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3653: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3653 Gene

Function for MIR3653 Gene

Phenotypes From GWAS Catalog for MIR3653 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3653 Gene

Localization for MIR3653 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3653 Gene

Pathways & Interactions for MIR3653 Gene

SuperPathways for MIR3653 Gene

No Data Available

Interacting Proteins for MIR3653 Gene

Gene Ontology (GO) - Biological Process for MIR3653 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3653 Gene

Drugs & Compounds for MIR3653 Gene

No Compound Related Data Available

Transcripts for MIR3653 Gene

mRNA/cDNA for MIR3653 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3653 Gene

No ASD Table

Relevant External Links for MIR3653 Gene

GeneLoc Exon Structure for
MIR3653
ECgene alternative splicing isoforms for
MIR3653

Expression for MIR3653 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3653 Gene:

MIR3653
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3653 Gene

Orthologs for MIR3653 Gene

Evolution for MIR3653 Gene

ENSEMBL:
Gene Tree for MIR3653 (if available)
TreeFam:
Gene Tree for MIR3653 (if available)

No data available for Orthologs for MIR3653 Gene

Paralogs for MIR3653 Gene

No data available for Paralogs for MIR3653 Gene

Variants for MIR3653 Gene

Sequence variations from dbSNP and Humsavar for MIR3653 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000132468 -- 29,335,222(-) C/T upstream_transcript_variant
rs1000449335 -- 29,333,866(-) C/A upstream_transcript_variant
rs1000800621 -- 29,333,702(-) G/C upstream_transcript_variant
rs1001127885 -- 29,333,019(-) G/C downstream_transcript_variant
rs1001181841 -- 29,333,217(-) C/T non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3653 Gene

Variant ID Type Subtype PubMed ID
nsv834171 CNV loss 17160897

Additional Variant Information for MIR3653 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3653

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3653 Gene

Disorders for MIR3653 Gene

Additional Disease Information for MIR3653

No disorders were found for MIR3653 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3653 Gene

Publications for MIR3653 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin BM … Amundadottir LT (Nature genetics 2014) 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 58
  3. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 58
  4. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 58

Products for MIR3653 Gene

Sources for MIR3653 Gene

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