microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3651 Gene

Subcategory (RNA class) for MIR3651 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR3651 Gene

  • MicroRNA 3651 2 3 5
  • Hsa-Mir-3651 2 3
  • Hsa-MiR-3651 163 173
  • MIR3651 2 5
  • MIMAT0018071 50
  • MI0016051 50
  • Mir-3651 3

External Ids for MIR3651 Gene

Previous GeneCards Identifiers for MIR3651 Gene

  • GC09U901627
  • GC09M095055

Summaries for MIR3651 Gene

Entrez Gene Summary for MIR3651 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3651 Gene

MIR3651 (MicroRNA 3651) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3651 include Polycystic Liver Disease and Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease.

Rfam classification for MIR3651 Gene

  • Small nucleolar RNA SNORA84

Additional gene information for MIR3651 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3651 Gene

Genomics for MIR3651 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3651 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J092291 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -1.2 -1229 5.6 ARHGAP35 CEBPG SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 REST ZNF629 IARS1 MIR3651 SNORA84 lnc-CENPP-17 lnc-NOL8-1 NOL8 MTND4P15 CENPP OGN MTCO3P29
GH09J092290 Enhancer 0.4 Ensembl 0.7 +2.2 2247 0.2 CEBPB BATF EBF1 IARS1 MIR3651 lnc-NOL8-1 lnc-NOL8-2 PRSS47
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3651 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3651 Gene

Genomic Locations for MIR3651 Gene
chr9:92,292,458-92,292,547
(GRCh38/hg38)
Size:
90 bases
Orientation:
Minus strand
chr9:95,054,740-95,054,829
(GRCh37/hg19)
Size:
90 bases
Orientation:
Minus strand

Genomic View for MIR3651 Gene

Genes around MIR3651 on UCSC Golden Path with GeneCards custom track
MIR3651 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3651 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3651 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3651 Gene

Proteins for MIR3651 Gene

Post-translational modifications for MIR3651 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3651 Gene

Domains & Families for MIR3651 Gene

Gene Families for MIR3651 Gene

HGNC:
genes like me logo Genes that share domains with MIR3651: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3651 Gene

Function for MIR3651 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3651 Gene

Localization for MIR3651 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3651 gene
Compartment Confidence
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MIR3651 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with MIR3651: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR3651 Gene

Pathways & Interactions for MIR3651 Gene

PathCards logo

SuperPathways for MIR3651 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3651 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with MIR3651: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3651 Gene

Drugs & Compounds for MIR3651 Gene

No Compound Related Data Available

Transcripts for MIR3651 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3651 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DEE5_9606 precursor_RNA 90 5

HGNC: 38897,

RefSeq: NR_037424,

Ensembl: ENST00000630427 (view in UCSC) ,

miRBase: MI0016051,

ENA: LM611182.1:1..90:precursor_RNA,

URS0000299AD8_9606 miRNA 24 5

RefSeq: NR_037424,

LncBase: hsa-miR-3651,

miRBase: MIMAT0018071,

TarBase: hsa-miR-3651,

ENA: LM382148.1:1..24:ncRNA, LM611182.1:64..87:ncRNA,

MIR3651 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3651 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3651 Gene

No ASD Table

Relevant External Links for MIR3651 Gene

GeneLoc Exon Structure for
MIR3651

Expression for MIR3651 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3651 Gene

Orthologs for MIR3651 Gene

Evolution for MIR3651 Gene

ENSEMBL:
Gene Tree for MIR3651 (if available)
TreeFam:
Gene Tree for MIR3651 (if available)

No data available for Orthologs for MIR3651 Gene

Paralogs for MIR3651 Gene

No data available for Paralogs for MIR3651 Gene

Variants for MIR3651 Gene

Additional dbSNP identifiers (rs#s) for MIR3651 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3651 Gene

Variant ID Type Subtype PubMed ID
esv3891693 CNV gain 25118596
nsv1046733 CNV gain 25217958

Additional Variant Information for MIR3651 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3651

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3651 Gene

Disorders for MIR3651 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR3651 Gene - From: DISEASES

Disorder Aliases PubMed IDs
polycystic liver disease
  • congenital cystic liver disease
polycystic kidney disease 4 with or without polycystic liver disease
  • pkd4
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3651

genes like me logo Genes that share disorders with MIR3651: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3651 Gene

Publications for MIR3651 Gene

  1. Prognostic significance of altered miRNA expression in whole blood of OSCC patients. (PMID: 28498442) Ries J … Nkenke E (Oncology reports 2017) 3
  2. Clinical potential of miR-3651 as a novel prognostic biomarker for esophageal squamous cell cancer. (PMID: 26210449) Wang C … Cheng Y (Biochemical and biophysical research communications 2015) 3
  3. miR-186, miR-3651 and miR-494: potential biomarkers for oral squamous cell carcinoma extracted from whole blood. (PMID: 24452363) Ries J … Nkenke E (Oncology reports 2014) 3
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  5. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3

Products for MIR3651 Gene

Sources for MIR3651 Gene