Aliases for MIR363 Gene
Subcategory (RNA class) for MIR363 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR363 Gene
- HGNC: 32023
- Entrez Gene: 574031
- Ensembl: ENSG00000284499
- miRBase: hsa-mir-363
ORGUL Members for MIR363 Gene
Previous HGNC Symbols for MIR363 Gene
- MIRN363
Previous GeneCards Identifiers for MIR363 Gene
- GC0XM133150
- GC0XM133157
- GC0XM133303
- GC0XM134170
- GC0XM134187
- GC0XM134193
Summaries for MIR363 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR363 Gene
MIR363 (MicroRNA 363) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Parkinsons Disease Pathway.
Additional gene information for MIR363 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR363 Gene
Genomics for MIR363 Gene
GeneHancer (GH) Regulatory Elements for MIR363 Gene
Promoters and enhancers for MIR363 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XI134148 | Enhancer | 0.4 | FANTOM5 | 13.1 | +20.9 | 20904 | 0.3 | CC2D1A RFX1 ZBTB5 | MIR363 ENSG00000200572 GC0XM134143 GC0XM134159 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR363 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR363 Gene
Genomic Locations for MIR363 Gene
- chrX:134,169,378-134,169,452
- (GRCh38/hg38)
- Size:
- 75 bases
- Orientation:
- Minus strand
- chrX:133,303,408-133,303,482
- (GRCh37/hg19)
Genomic View for MIR363 Gene
Genes around MIR363 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq26.2 by Ensembl
- Xq26.2 by Entrez Gene
- Xq26.2 by HGNC
MIR363 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR363 Gene
Proteins for MIR363 Gene
Post-translational modifications for MIR363 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR363
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR363
- Origene Custom Protein Services for MIR363
- Search GeneTex for Proteins for MIR363
No data available for DME Specific Peptides for MIR363 Gene
Domains & Families for MIR363 Gene
Gene Families for MIR363 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR363 Gene
Function for MIR363 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:1903231 | mRNA binding involved in posttranscriptional gene silencing | IDA | 20190813 |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR363
-
- Search ViGene Biosciences for MIR363
CRISPR Products
- Browse CRISPR knockouts for MIR363
- Applied Biological Materials CRISPR for MIR363
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR363
Clone Products
- GenScript: Custom all cDNA clones Services for MIR363
- VectorBuilder custom plasmid, inducible vectors for MIR363
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR363
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR363
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR363 Gene
Localization for MIR363 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IDA | 26646931 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR363 Gene
Pathways & Interactions for MIR363 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | MicroRNAs in cancer | ||
| 2 | Parkinsons Disease Pathway | ||
Pathways by source for MIR363 Gene
1 BioSystems pathway for MIR363 Gene
1 KEGG pathway for MIR363 Gene
Interacting Proteins for MIR363 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0035195 | gene silencing by miRNA | IDA | 20190813 |
No data available for SIGNOR curated interactions for MIR363 Gene
Transcripts for MIR363 Gene
mRNA/cDNA for MIR363 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR363
- Applied Biological Materials CRISPR for MIR363
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR363
Clone Products
- GenScript: Custom all cDNA clones Services for MIR363
- VectorBuilder custom plasmid, inducible vectors for MIR363
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR363
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR363
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR363 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR363 Gene:
MIR363
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR363 Gene
Orthologs for MIR363 Gene
No data available for Orthologs for MIR363 Gene
Paralogs for MIR363 Gene
No data available for Paralogs for MIR363 Gene
Variants for MIR363 Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1003224417 | -- | 134,168,950(-) | G/A | downstream_transcript_variant | |
| rs1003822325 | -- | 134,171,007(-) | T/C | upstream_transcript_variant | |
| rs1004902717 | -- | 134,170,953(-) | A/G | upstream_transcript_variant | |
| rs1005828091 | -- | 134,169,983(-) | T/G | upstream_transcript_variant | |
| rs1007316405 | -- | 134,171,110(-) | G/A | upstream_transcript_variant |
Additional Variant Information for MIR363 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR363
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR363 Gene
Disorders for MIR363 Gene
Additional Disease Information for MIR363
No disorders were found for MIR363 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR363 Gene
Publications for MIR363 Gene
- miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma. (PMID: 28423618) Wang Y … Liu G (Oncotarget 2017) 3 58
- Dendritic Cells from Rheumatoid Arthritis Patient Peripheral Blood Induce Th17 Cell Differentiation via miR-363/Integrin αv/TGF-β Axis. (PMID: 28376277) Pan F … Cai C (Scandinavian journal of immunology 2017) 3 58
- Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
- miR-363 induces transdifferentiation of human kidney tubular cells to mesenchymal phenotype. (PMID: 26373846) Morizane R … Itoh H (Clinical and experimental nephrology 2016) 3 58
- Oncogenic cAMP responsive element binding protein 1 is overexpressed upon loss of tumor suppressive miR-10b-5p and miR-363-3p in renal cancer. (PMID: 26796749) Li Y … Lai Y (Oncology reports 2016) 3 58
Products for MIR363 Gene
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- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
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- Browse Proteins and Enzymes
- Browse ELISAs
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR363
- VectorBuilder custom plasmid, inducible vectors for MIR363
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR363
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR363
- Search GeneTex for Proteins for MIR363
- Search ViGene Biosciences for MIR363
Sources for MIR363 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems