microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3620 Gene

Data sources for MIR3620 Gene:

RNA type for MIR3620 Gene

miRNA

Aliases for MIR3620 Gene

External Ids for MIR3620 Gene

Previous GeneCards Identifiers for MIR3620 Gene

  • GC01U903105
  • GC01P228288

Summaries for MIR3620 Gene

Entrez Gene Summary for MIR3620 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3620 Gene

MIR3620 (MicroRNA 3620) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Glycerophospholipid biosynthesis and Golgi-to-ER retrograde transport.

Additional gene information for MIR3620 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3620 Gene

Genomics for MIR3620 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3620 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J228098 Enhancer 0.6 Ensembl 250.7 +1.3 1309 0.5 BCLAF1 POLR2A KLF7 CTCF SUPT5H ZNF189 PAF1 GLIS2 POLR2B RBFOX2 6HTU_D HSALNG0011193 MIR3620 piR-47559 C1orf35 ARF1
GH01J228096 Enhancer 0.5 ENCODE 250.7 -1.2 -1155 0.1 ZNF837 ZNF18 EGR2 ZNF660 ZFHX2 6HTU_D MIR3620 piR-47559 MRPL55 HSALNG0011192 C1orf35 ARF1
GH01J228092 Enhancer 0.5 dbSUPER 0.7 -4.6 -4558 0.9 POLR2A SMARCE1 DPF2 ZNF560 ZNF579 HSALNG0011192 IBA57-DT RPL23AP15 H2AW H2BU1 MIR3620 ARF1 C1orf35
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3620 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3620 Gene

Latest Assembly
chr1:228,097,263-228,097,341
(GRCh38/hg38)
Size:
79 bases
Orientation:
Plus strand

Previous Assembly
chr1:228,284,964-228,285,042
(GRCh37/hg19 by Entrez Gene)
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR3620 Gene

Genes around MIR3620 on UCSC Golden Path with GeneCards custom track
MIR3620 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3620 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3620 Gene

Proteins for MIR3620 Gene

Post-translational modifications for MIR3620 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3620 Gene

Domains & Families for MIR3620 Gene

Gene Families for MIR3620 Gene

HGNC:
genes like me logo Genes that share domains with MIR3620: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3620 Gene

Function for MIR3620 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3620 Gene

Localization for MIR3620 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3620 gene
Compartment Confidence
extracellular 1
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3620 Gene

Pathways & Interactions for MIR3620 Gene

genes like me logo Genes that share pathways with MIR3620: view

Gene Ontology (GO) - Biological Process for MIR3620 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3620 Gene

Drugs & Compounds for MIR3620 Gene

No Compound Related Data Available

Transcripts for MIR3620 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3620 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075F100_9606 precursor_RNA 79 4

RefSeq: NR_037415,

Ensembl: ENST00000584469 (view in UCSC) ,

miRBase: MI0016011,

ENA: LM611177.1:1..79:precursor_RNA,

URS000075C163_9606 miRNA 22 4

RefSeq: NR_037415,

miRBase: MIMAT0018001,

TarBase: hsa-miR-3620-3p,

ENA: LM611177.1:58..79:ncRNA,

URS00004818BD_9606 miRNA 22 3

RefSeq: NR_037415,

miRBase: MIMAT0022967,

ENA: LM383093.1:1..22:ncRNA, LM611177.1:23..44:ncRNA,

MIR3620 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3620 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3620 Gene

No ASD Table

Relevant External Links for MIR3620 Gene

GeneLoc Exon Structure for
MIR3620

Expression for MIR3620 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3620 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3620

genes like me logo Genes that share expression patterns with MIR3620: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3620 Gene

Orthologs for MIR3620 Gene

Evolution for MIR3620 Gene

ENSEMBL:
Gene Tree for MIR3620 (if available)
TreeFam:
Gene Tree for MIR3620 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3620

No data available for Orthologs for MIR3620 Gene

Paralogs for MIR3620 Gene

No data available for Paralogs for MIR3620 Gene

Variants for MIR3620 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3620 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3620 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv1160102 CNV deletion 26073780
nsv516409 CNV loss 19592680
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv832803 CNV loss 17160897
nsv952136 CNV deletion 24416366

Additional Variant Information for MIR3620 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3620
Leiden Open Variation Database (LOVD)
MIR3620

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3620 Gene

Disorders for MIR3620 Gene

Additional Disease Information for MIR3620

No disorders were found for MIR3620 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3620 Gene

Publications for MIR3620 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3620 Gene

Sources for MIR3620 Gene