microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3619 Gene

Data sources for MIR3619 Gene:

RNA type for MIR3619 Gene

miRNA

Aliases for MIR3619 Gene

External Ids for MIR3619 Gene

Previous GeneCards Identifiers for MIR3619 Gene

  • GC22U900743
  • GC22P046489

Summaries for MIR3619 Gene

Entrez Gene Summary for MIR3619 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3619 Gene

MIR3619 (MicroRNA 3619) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3619 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3619 Gene

Genomics for MIR3619 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3619 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J046040 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -22.8 -22837 55.6 SP1 MYC ZNF600 IKZF1 JUND ZNF580 ZNF592 ATF2 ZNF223 ZNF10 ENSG00000235159 PRR34 MN297931 PRR34-AS1 MIRLET7BHG CDPF1 TRMU LINC00899 ENSG00000273243 ATXN10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3619 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3619 Gene

Latest Assembly
chr22:46,091,044-46,091,126
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand

Previous Assembly
chr22:46,486,924-46,487,006
(GRCh37/hg19 by Entrez Gene)
Size:
83 bases
Orientation:
Plus strand

chr22:46,486,924-46,487,006
(GRCh37/hg19 by Ensembl)
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR3619 Gene

Genes around MIR3619 on UCSC Golden Path with GeneCards custom track
MIR3619 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3619 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3619 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3619 Gene

Proteins for MIR3619 Gene

Post-translational modifications for MIR3619 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3619 Gene

Domains & Families for MIR3619 Gene

Gene Families for MIR3619 Gene

HGNC:
genes like me logo Genes that share domains with MIR3619: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3619 Gene

Function for MIR3619 Gene

Phenotypes From GWAS Catalog for MIR3619 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3619 Gene

Localization for MIR3619 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3619 Gene

Pathways & Interactions for MIR3619 Gene

PathCards logo

SuperPathways for MIR3619 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3619 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3619 Gene

Drugs & Compounds for MIR3619 Gene

No Compound Related Data Available

Transcripts for MIR3619 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3619 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000053966D_9606 miRNA 22 5

RefSeq: NR_037413,

LncBase: hsa-miR-3619-5p,

miRBase: MIMAT0017999,

MirGeneDB: Hsa-Mir-3619_5p,

TarBase: hsa-miR-3619-5p,

URS000061BAF5_9606 miRNA 22 5

RefSeq: NR_037413,

LncBase: hsa-miR-3619-3p,

miRBase: MIMAT0019219,

TarBase: hsa-miR-3619-3p,

ENA: FR772790.1:1..22:ncRNA,

URS000075C055_9606 pre_miRNA 83 3

RefSeq: NR_037413,

Ensembl: ENST00000579667 (view in UCSC) ,

miRBase: MI0016009,

URS0000EFCDA3_9606 precursor_RNA 55 1

MirGeneDB: Hsa-Mir-3619,

URS0000103040_9606 miRNA 23 1

ENA: FR772791.1:1..23:ncRNA,

MIR3619 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3619 Gene

No ASD Table

Relevant External Links for MIR3619 Gene

GeneLoc Exon Structure for
MIR3619

No data available for mRNA/cDNA for MIR3619 Gene

Expression for MIR3619 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3619 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3619

genes like me logo Genes that share expression patterns with MIR3619: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3619 Gene

Orthologs for MIR3619 Gene

Evolution for MIR3619 Gene

ENSEMBL:
Gene Tree for MIR3619 (if available)
TreeFam:
Gene Tree for MIR3619 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3619

No data available for Orthologs for MIR3619 Gene

Paralogs for MIR3619 Gene

No data available for Paralogs for MIR3619 Gene

Variants for MIR3619 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3619 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3619 Gene

Variant ID Type Subtype PubMed ID
dgv2469n106 OTHER inversion 24896259
dgv776n67 CNV gain 20364138
nsv1152661 OTHER inversion 26484159
nsv459904 CNV loss 19166990
nsv471212 CNV loss 18288195
nsv471213 CNV gain 18288195
nsv516279 CNV loss 19592680
nsv589132 CNV loss 21841781
nsv829281 CNV gain 20364138
nsv829285 CNV gain 20364138

Additional Variant Information for MIR3619 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3619
Leiden Open Variation Database (LOVD)
MIR3619

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3619 Gene

Disorders for MIR3619 Gene

Additional Disease Information for MIR3619

No disorders were found for MIR3619 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3619 Gene

Publications for MIR3619 Gene

  1. Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro. (PMID: 32437796) Hao P … Wang Y (Life sciences 2020) 3
  2. CircZFR promotes hepatocellular carcinoma progression through regulating miR-3619-5p/CTNNB1 axis and activating Wnt/β-catenin pathway. (PMID: 30468709) Tan A … Chen L (Archives of biochemistry and biophysics 2019) 3
  3. Long Noncoding RNA LINC00202 Promotes Tumor Progression by Sponging miR-3619-5p in Retinoblastoma. (PMID: 30905893) Yan G … Chen N (Cell structure and function 2019) 3
  4. MiR-3619-5p hampers proliferation and cisplatin resistance in cutaneous squamous-cell carcinoma via KPNA4. (PMID: 30967266) Zhang M … Hui L (Biochemical and biophysical research communications 2019) 3
  5. Long non-coding RNA00882 contributes to platelet-derived growth factor-induced proliferation of human fetal airway smooth muscle cells by enhancing Wnt/β-catenin signaling via sponging miR-3619-5p. (PMID: 31014672) Liu Z … He Z (Biochemical and biophysical research communications 2019) 3

Products for MIR3619 Gene

Sources for MIR3619 Gene