microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3618 Gene

Data sources for MIR3618 Gene:

RNA type for MIR3618 Gene

miRNA

Aliases for MIR3618 Gene

External Ids for MIR3618 Gene

Previous GeneCards Identifiers for MIR3618 Gene

  • GC22U900749
  • GC22P020078

Summaries for MIR3618 Gene

Entrez Gene Summary for MIR3618 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3618 Gene

MIR3618 (MicroRNA 3618) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Tat-mediated elongation of the HIV-1 transcript and DDX1 as a regulatory component of the Drosha microprocessor.

Additional gene information for MIR3618 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3618 Gene

Genomics for MIR3618 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3618 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J020084 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 250.7 -0.8 -823 1.4 NCOR1 IKZF1 MYC MXD4 REST HES1 BHLHE40 ZNF341 MNT CTCF MIR1306 MIR3618 DGCR8 TRMT2A LZTR1 LINC01311 MED15 ENSG00000215493 RPL7AP70 ESS2
GH22J020085 Promoter/Enhancer 0.7 EPDnew dbSUPER 250.7 +0.1 56 0.1 MLLT1 ZBTB33 NFXL1 MIR1306 MIR3618 DGCR8 RANBP1
GH22J020078 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -4.2 -4225 5.2 SP1 IKZF1 MYC NCOR1 SIX5 ZNF580 ATF2 CEBPA POLR2A ZIC2 DGCR8 lnc-TRMT2A-3 TRMT2A LZTR1 MED15 UFD1 RPL7AP70 RPL8P5 RANBP1 LINC01311
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3618 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3618 Gene

Latest Assembly
chr22:20,085,746-20,085,833
(GRCh38/hg38)
Size:
88 bases
Orientation:
Plus strand

Previous Assembly
chr22:20,073,269-20,073,356
(GRCh37/hg19 by Entrez Gene)
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR3618 Gene

Genes around MIR3618 on UCSC Golden Path with GeneCards custom track
MIR3618 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3618 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3618 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3618 Gene

Proteins for MIR3618 Gene

Post-translational modifications for MIR3618 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3618 Gene

Domains & Families for MIR3618 Gene

Gene Families for MIR3618 Gene

HGNC:
genes like me logo Genes that share domains with MIR3618: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3618 Gene

Function for MIR3618 Gene

Phenotypes From GWAS Catalog for MIR3618 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3618 Gene

Localization for MIR3618 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3618 Gene

Pathways & Interactions for MIR3618 Gene

genes like me logo Genes that share pathways with MIR3618: view

Pathways by source for MIR3618 Gene

Gene Ontology (GO) - Biological Process for MIR3618 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3618 Gene

Drugs & Compounds for MIR3618 Gene

No Compound Related Data Available

Transcripts for MIR3618 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3618 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075BA45_9606 precursor_RNA 88 3

RefSeq: NR_037412,

Ensembl: ENST00000580330 (view in UCSC) ,

miRBase: MI0016008,

URS000075E3B9_9606 miRNA 22 2

RefSeq: NR_037412,

miRBase: MIMAT0017998,

MIR3618 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3618 Gene

No ASD Table

Relevant External Links for MIR3618 Gene

GeneLoc Exon Structure for
MIR3618

No data available for mRNA/cDNA for MIR3618 Gene

Expression for MIR3618 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3618 Gene

genes like me logo Genes that share expression patterns with MIR3618: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3618 Gene

Orthologs for MIR3618 Gene

Evolution for MIR3618 Gene

ENSEMBL:
Gene Tree for MIR3618 (if available)
TreeFam:
Gene Tree for MIR3618 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3618

No data available for Orthologs for MIR3618 Gene

Paralogs for MIR3618 Gene

No data available for Paralogs for MIR3618 Gene

Variants for MIR3618 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3618 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3618 Gene

Variant ID Type Subtype PubMed ID
dgv4480n100 CNV gain 25217958
dgv726n67 CNV gain 20364138
dgv7983n54 CNV gain 21841781
esv2758825 CNV loss 17122850
esv3647284 CNV gain 21293372
esv3893434 CNV gain 25118596
nsv471183 CNV loss 18288195
nsv828938 CNV gain 20364138
nsv828939 CNV loss 20364138
nsv834133 CNV loss 17160897
nsv953027 CNV deletion 24416366

Additional Variant Information for MIR3618 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3618
Leiden Open Variation Database (LOVD)
MIR3618

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3618 Gene

Disorders for MIR3618 Gene

Additional Disease Information for MIR3618

No disorders were found for MIR3618 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3618 Gene

Publications for MIR3618 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3618 Gene

Sources for MIR3618 Gene