microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3616 Gene

Subcategory (RNA class) for MIR3616 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR3616 Gene

  • MicroRNA 3616 2 3 5
  • Hsa-Mir-3616 2 3
  • MIR3616 2 5
  • MIMAT0017996 50
  • MIMAT0017995 50
  • MI0016006 50
  • Mir-3616 3

External Ids for MIR3616 Gene

Previous GeneCards Identifiers for MIR3616 Gene

  • GC20U900639
  • GC20P045798

Summaries for MIR3616 Gene

Entrez Gene Summary for MIR3616 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3616 Gene

MIR3616 (MicroRNA 3616) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3616 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3616 Gene

Genomics for MIR3616 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3616 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J047164 Enhancer 0.2 Ensembl 0.7 -2.9 -2866 0.2 MIR3616 RPS2P54 ZMYND8 EYA2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3616 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3616 Gene

Genomic Locations for MIR3616 Gene
chr20:47,166,967-47,167,058
(GRCh38/hg38)
Size:
92 bases
Orientation:
Plus strand
chr20:45,795,609-45,795,700
(GRCh37/hg19)
Size:
92 bases
Orientation:
Plus strand

Genomic View for MIR3616 Gene

Genes around MIR3616 on UCSC Golden Path with GeneCards custom track
MIR3616 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3616 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3616 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3616 Gene

Proteins for MIR3616 Gene

Post-translational modifications for MIR3616 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3616 Gene

Domains & Families for MIR3616 Gene

Gene Families for MIR3616 Gene

HGNC:
genes like me logo Genes that share domains with MIR3616: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3616 Gene

Function for MIR3616 Gene

Phenotypes From GWAS Catalog for MIR3616 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3616 Gene

Localization for MIR3616 Gene

Gene Ontology (GO) - Cellular Components for MIR3616 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR3616: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3616 Gene

Pathways & Interactions for MIR3616 Gene

PathCards logo

SuperPathways for MIR3616 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3616 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3616 Gene

Drugs & Compounds for MIR3616 Gene

No Compound Related Data Available

Transcripts for MIR3616 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3616 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D53C_9606 precursor_RNA 92 5

HGNC: 38943,

RefSeq: NR_037410,

Ensembl: ENST00000584070 (view in UCSC) ,

miRBase: MI0016006,

ENA: LM611175.1:1..92:precursor_RNA,

URS000075D1FC_9606 miRNA 23 3

RefSeq: NR_037410,

miRBase: MIMAT0017996,

ENA: LM382142.1:1..23:ncRNA, LM611175.1:60..82:ncRNA,

URS000075EF21_9606 miRNA 22 3

RefSeq: NR_037410,

miRBase: MIMAT0017995,

ENA: LM611175.1:19..40:ncRNA,

MIR3616 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3616 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3616 Gene

No ASD Table

Relevant External Links for MIR3616 Gene

GeneLoc Exon Structure for
MIR3616

Expression for MIR3616 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3616 Gene

genes like me logo Genes that share expression patterns with MIR3616: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3616 Gene

Orthologs for MIR3616 Gene

Evolution for MIR3616 Gene

ENSEMBL:
Gene Tree for MIR3616 (if available)
TreeFam:
Gene Tree for MIR3616 (if available)

No data available for Orthologs for MIR3616 Gene

Paralogs for MIR3616 Gene

No data available for Paralogs for MIR3616 Gene

Variants for MIR3616 Gene

Additional dbSNP identifiers (rs#s) for MIR3616 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3616 Gene

Variant ID Type Subtype PubMed ID
esv33497 CNV loss 17666407
nsv1061899 CNV loss 25217958

Additional Variant Information for MIR3616 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3616

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3616 Gene

Disorders for MIR3616 Gene

Additional Disease Information for MIR3616

No disorders were found for MIR3616 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3616 Gene

Publications for MIR3616 Gene

  1. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3616 Gene

Sources for MIR3616 Gene