microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3615 Gene

Data sources for MIR3615 Gene:

Subcategory (RNA class) for MIR3615 Gene

miRNA

Aliases for MIR3615 Gene

External Ids for MIR3615 Gene

Previous GeneCards Identifiers for MIR3615 Gene

  • GC17U901553
  • GC17P072747

Summaries for MIR3615 Gene

Entrez Gene Summary for MIR3615 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3615 Gene

MIR3615 (MicroRNA 3615) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3615 include Retinitis Pigmentosa 41 and Retinitis Pigmentosa 27.

Additional gene information for MIR3615 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3615 Gene

Genomics for MIR3615 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3615 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J074746 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 +1.8 1777 8.6 CHD2 TBP SP1 MXD4 CEBPA IKZF1 SMAD5 MBD2 POLR2A CTCF SLC9A3R1 ENSG00000266036 MIR3615 SLC9A3R1-AS1 NUP85 NT5C NAT9 GGA3 RAB37 TSEN54
GH17J074744 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -3.5 -3505 1.8 ZBTB10 MXD4 DEK ZNF217 CTCF ZEB1 NONO ZNF610 THAP11 REST HSALNG0118679 ENSG00000266036 MIR3615 SLC9A3R1 CD300LF RAB37
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3615 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3615 Gene

Latest Assembly
chr17:74,748,613-74,748,699
(GRCh38/hg38)
Size:
87 bases
Orientation:
Plus strand

Previous Assembly
chr17:72,744,752-72,744,838
(GRCh37/hg19 by Entrez Gene)
Size:
87 bases
Orientation:
Plus strand

Genomic View for MIR3615 Gene

Genes around MIR3615 on UCSC Golden Path with GeneCards custom track
MIR3615 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3615 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3615 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3615 Gene

Proteins for MIR3615 Gene

Post-translational modifications for MIR3615 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3615 Gene

Domains & Families for MIR3615 Gene

Gene Families for MIR3615 Gene

HGNC:
genes like me logo Genes that share domains with MIR3615: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3615 Gene

Function for MIR3615 Gene

Phenotypes From GWAS Catalog for MIR3615 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3615 Gene

Localization for MIR3615 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3615 gene
Compartment Confidence
nucleus 1

Gene Ontology (GO) - Cellular Components for MIR3615 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR3615: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR3615 Gene

Pathways & Interactions for MIR3615 Gene

PathCards logo

SuperPathways for MIR3615 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3615 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3615 Gene

Drugs & Compounds for MIR3615 Gene

No Compound Related Data Available

Transcripts for MIR3615 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3615 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000011166D_9606 miRNA 21 5

RefSeq: NR_037409,

LncBase: hsa-miR-3615,

miRBase: MIMAT0017994,

TarBase: hsa-miR-3615,

ENA: LM382141.1:1..21:ncRNA, LM611174.1:51..71:ncRNA,

URS000075A6B9_9606 precursor_RNA 87 4

RefSeq: NR_037409,

Ensembl: ENST00000581999 (view in UCSC) ,

miRBase: MI0016005,

ENA: LM611174.1:1..87:precursor_RNA,

MIR3615 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3615 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3615 Gene

No ASD Table

Relevant External Links for MIR3615 Gene

GeneLoc Exon Structure for
MIR3615

Expression for MIR3615 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3615 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3615 Gene

This gene is overexpressed in Testis (x22.2), Kidney - Cortex (x11.3), and Small Intestine - Terminal Ileum (x9.6).
genes like me logo Genes that share expression patterns with MIR3615: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3615 Gene

Orthologs for MIR3615 Gene

Evolution for MIR3615 Gene

ENSEMBL:
Gene Tree for MIR3615 (if available)
TreeFam:
Gene Tree for MIR3615 (if available)

No data available for Orthologs for MIR3615 Gene

Paralogs for MIR3615 Gene

No data available for Paralogs for MIR3615 Gene

Variants for MIR3615 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3615 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR3615 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3615

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3615 Gene

Disorders for MIR3615 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR3615 Gene - From: COP

Disorder Aliases PubMed IDs
retinitis pigmentosa 41
  • rp41
retinitis pigmentosa 27
  • rp27
usher syndrome, type ig
  • ush1g
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3615

genes like me logo Genes that share disorders with MIR3615: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3615 Gene

Publications for MIR3615 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3615 Gene

Sources for MIR3615 Gene