microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3613 Gene

Subcategory (RNA class) for MIR3613 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR3613 Gene

  • MicroRNA 3613 2 3 5
  • Hsa-MiR-3613-3p 166 177
  • Hsa-MiR-3613-5p 166 177
  • Hsa-Mir-3613 3
  • MIMAT0017990 51
  • MIMAT0017991 51
  • MI0016003 51
  • MIR3613 2

External Ids for MIR3613 Gene

Previous GeneCards Identifiers for MIR3613 Gene

  • GC13U900807
  • GC13M050574

Summaries for MIR3613 Gene

Entrez Gene Summary for MIR3613 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3613 Gene

MIR3613 (MicroRNA 3613) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3613 include Central Nervous System Primitive Neuroectodermal Neoplasm and Medulloepithelioma.

Additional gene information for MIR3613 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3613 Gene

Genomics for MIR3613 Gene

GeneHancer (GH) Regulatory Elements for MIR3613 Gene

Promoters and enhancers for MIR3613 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J049995 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 -1.3 -1259 4.9 HNRNPK CTCF SIN3A TCF12 POLR2G PHF8 ZFX ZNF639 EP300 ZIC2 TRIM13 SPRYD7 MIR3613 KCNRG SETDB2 DLEU1 EBPL CTAGE10P RNASEH2B DLEU2
GH13J050012 Enhancer 0.4 Ensembl 0.4 -16.6 -16587 1.4 ZNF316 MAFF MAFK HLF EMSY KCNRG MIR3613 TRIM13 DLEU2
GH13J050005 Enhancer 0.3 Ensembl 0.4 -8.9 -8900 0.8 POLR2A ZNF202 KCNRG MIR3613 TRIM13 DLEU2
GH13J050006 Enhancer 0.3 Ensembl 0.4 -10.1 -10100 0.4 ZNF680 PRDM1 KCNRG MIR3613 TRIM13 DLEU2
GH13J050007 Enhancer 0.2 Ensembl 0.4 -10.9 -10900 0.4 TRIM13 KCNRG MIR3613 DLEU2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3613 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3613 Gene

Genomic Locations for MIR3613 Gene
chr13:49,996,415-49,996,501
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand
chr13:50,570,551-50,570,637
(GRCh37/hg19)
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR3613 Gene

Genes around MIR3613 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3613 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3613 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3613 Gene

Proteins for MIR3613 Gene

Post-translational modifications for MIR3613 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3613 Gene

Domains & Families for MIR3613 Gene

Gene Families for MIR3613 Gene

HGNC:
genes like me logo Genes that share domains with MIR3613: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3613 Gene

Function for MIR3613 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3613 Gene

Localization for MIR3613 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3613 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3613 Gene

Pathways & Interactions for MIR3613 Gene

PathCards logo

SuperPathways for MIR3613 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR3613 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3613 Gene

Drugs & Compounds for MIR3613 Gene

No Compound Related Data Available

Transcripts for MIR3613 Gene

mRNA/cDNA for MIR3613 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
5 ENA transcripts :
2 LncBase transcripts :
2 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3613 Gene

No ASD Table

Relevant External Links for MIR3613 Gene

GeneLoc Exon Structure for
MIR3613

Expression for MIR3613 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3613 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3613

genes like me logo Genes that share expression patterns with MIR3613: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3613 Gene

Orthologs for MIR3613 Gene

Evolution for MIR3613 Gene

ENSEMBL:
Gene Tree for MIR3613 (if available)
TreeFam:
Gene Tree for MIR3613 (if available)

No data available for Orthologs for MIR3613 Gene

Paralogs for MIR3613 Gene

No data available for Paralogs for MIR3613 Gene

Variants for MIR3613 Gene

Additional dbSNP identifiers (rs#s) for MIR3613 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3613 Gene

Variant ID Type Subtype PubMed ID
nsv1035151 CNV loss 25217958
nsv1118263 CNV deletion 24896259
nsv561618 CNV loss 21841781

Additional Variant Information for MIR3613 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3613

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3613 Gene

Disorders for MIR3613 Gene

MalaCards: The human disease database

(5) MalaCards diseases for MIR3613 Gene - From: DISEASES

Disorder Aliases PubMed IDs
central nervous system primitive neuroectodermal neoplasm
  • cpnet
medulloepithelioma
  • diktyoma, malignant
synovium cancer
  • malignant tumor of synovium
sarcoma, synovial
  • synovial sarcoma
connective tissue cancer
  • connective tissue neoplasm
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3613

genes like me logo Genes that share disorders with MIR3613: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3613 Gene

Publications for MIR3613 Gene

  1. Impact of endurance exercise training on adipocyte microRNA expression in overweight men. (PMID: 27682205) Tsiloulis T … Watt MJ (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017) 2 3 54
  2. Exogenous expression of miRNA-3613-3p causes APAF1 downregulation and affects several proteins involved in apoptosis in BE(2)-C human neuroblastoma cells. (PMID: 30066861) Nowak I … Rokita H (International journal of oncology 2018) 3 54
  3. Whole blood miRNA expression analysis reveals miR-3613-3p as a potential biomarker for dedifferentiated liposarcoma. (PMID: 29689704) Fricke A … Eisenhardt SU (Cancer biomarkers : section A of Disease markers 2018) 3 54
  4. Monocyte Chemoattractant Protein-Induced Protein 1 Overexpression Modulates Transcriptome, Including MicroRNA, in Human Neuroblastoma Cells. (PMID: 26308737) Boratyn E … Rokita H (Journal of cellular biochemistry 2016) 3 54
  5. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 54

Products for MIR3613 Gene

Sources for MIR3613 Gene