microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3610 Gene

Data sources for MIR3610 Gene:

RNA type for MIR3610 Gene

miRNA

Aliases for MIR3610 Gene

External Ids for MIR3610 Gene

Previous GeneCards Identifiers for MIR3610 Gene

  • GC08U901480
  • GC08M117888

Summaries for MIR3610 Gene

Entrez Gene Summary for MIR3610 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3610 Gene

MIR3610 (MicroRNA 3610) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3610 include Acth Deficiency, Isolated and Hypopituitarism. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cell Cycle, Mitotic.

Additional gene information for MIR3610 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3610 Gene

Genomics for MIR3610 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3610 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J116869 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 +1.9 1936 5.9 ZNF207 MYC IKZF1 CEBPA BRCA1 ZIC2 POLR2A YY1 CEBPB SMAD5 RAD21 HSALNG0067947 MIR3610 RAD21-AS1 UTP23 RF00994-1084 EIF3H
GH08J116878 Enhancer 1.1 FANTOM5 Ensembl dbSUPER 0.7 -4.4 -4379 0.4 NCOR1 HES1 TAL1 ZNF316 NFE2 FOXM1 HDAC2 MAFK MAFG JUND HSALNG0067949 piR-60073 RAD21 UTP23 MIR3610 AARD
GH08J116877 Enhancer 1.1 FANTOM5 Ensembl dbSUPER 0.7 -3.0 -3001 0.8 MYC CEBPA CEBPB EP300 NBN PRDM6 ATF1 IRF9 SMARCA4 EHMT2 RAD21 MIR3610 piR-60073 AARD
GH08J116879 Enhancer 0.6 Ensembl dbSUPER 0.7 -3.7 -3701 0.2 ZNF512 RNF2 MCM7 HSALNG0067949 piR-60073 MIR3610 RAD21 AARD
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3610 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3610 Gene

Latest Assembly
chr8:116,874,728-116,874,800
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand

Previous Assembly
chr8:117,886,967-117,887,039
(GRCh37/hg19 by Entrez Gene)
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR3610 Gene

Genes around MIR3610 on UCSC Golden Path with GeneCards custom track
MIR3610 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3610 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3610 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3610 Gene

Proteins for MIR3610 Gene

Post-translational modifications for MIR3610 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3610 Gene

Domains & Families for MIR3610 Gene

Gene Families for MIR3610 Gene

HGNC:
genes like me logo Genes that share domains with MIR3610: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3610 Gene

Function for MIR3610 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3610 Gene

Localization for MIR3610 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3610 Gene

Pathways & Interactions for MIR3610 Gene

genes like me logo Genes that share pathways with MIR3610: view

Pathways by source for MIR3610 Gene

Gene Ontology (GO) - Biological Process for MIR3610 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3610 Gene

Drugs & Compounds for MIR3610 Gene

No Compound Related Data Available

Transcripts for MIR3610 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3610 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075EC53_9606 precursor_RNA 73 4

RefSeq: NR_037404,

Ensembl: ENST00000582903 (view in UCSC) ,

miRBase: MI0016000,

ENA: LM611170.1:1..73:precursor_RNA,

URS0000582627_9606 miRNA 20 3

RefSeq: NR_037404,

miRBase: MIMAT0017987,

ENA: LM382135.1:1..20:ncRNA, LM611170.1:42..61:ncRNA,

MIR3610 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3610 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3610 Gene

No ASD Table

Relevant External Links for MIR3610 Gene

GeneLoc Exon Structure for
MIR3610

Expression for MIR3610 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3610 Gene

Orthologs for MIR3610 Gene

Evolution for MIR3610 Gene

ENSEMBL:
Gene Tree for MIR3610 (if available)
TreeFam:
Gene Tree for MIR3610 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3610

No data available for Orthologs for MIR3610 Gene

Paralogs for MIR3610 Gene

No data available for Paralogs for MIR3610 Gene

Variants for MIR3610 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3610 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3610 Gene

Variant ID Type Subtype PubMed ID
nsv1144231 CNV deletion 24896259
nsv6359 CNV insertion 18451855
nsv831434 CNV gain 17160897

Additional Variant Information for MIR3610 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3610
Leiden Open Variation Database (LOVD)
MIR3610

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3610 Gene

Disorders for MIR3610 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR3610 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
acth deficiency, isolated
  • iad
hypopituitarism
  • pituitary hormone deficiency
trichorhinophalangeal syndrome, type ii
  • trps2
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3610

genes like me logo Genes that share disorders with MIR3610: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3610 Gene

Publications for MIR3610 Gene

  1. Circulating MicroRNAs as Potential Biomarkers for Traumatic Brain Injury-Induced Hypopituitarism. (PMID: 27027233) Taheri S … Kelestimur F (Journal of neurotrauma 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3610 Gene

Sources for MIR3610 Gene