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Aliases for MIR323B Gene

Subcategory (RNA class) for MIR323B Gene


Quality Score for this RNA gene is


Aliases for MIR323B Gene

  • MicroRNA 323b 2 3 5
  • MicroRNA 453 2 3
  • Hsa-Mir-323b 3
  • Hsa-Mir-453 3
  • Mir-323b 3
  • MIRN453 3
  • MIR453 3

External Ids for MIR323B Gene

ORGUL Members for MIR323B Gene

Previous HGNC Symbols for MIR323B Gene

  • MIR453
  • MIRN453

Previous GeneCards Identifiers for MIR323B Gene

  • GC14P101602
  • GC14P081705
  • GC14P101667
  • GC14P101702
  • GC14P101740
  • GC14P101779
  • GC14P101837
  • GC14P101977
  • GC14P102175
  • GC14P101268
  • GC14P101877
  • GC14P102200
  • GC14P102368
  • GC14P102538
  • GC14P102717
  • GC14P102890
  • GC14P103063

Summaries for MIR323B Gene

Entrez Gene Summary for MIR323B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR323B Gene

MIR323B (MicroRNA 323b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR323B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR323B Gene

Genomics for MIR323B Gene

GeneHancer (GH) Regulatory Elements for MIR323B Gene

Promoters and enhancers for MIR323B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J101004 Enhancer 0.7 Ensembl ENCODE 11 -51.1 -51134 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR323B MIR485 MIR154 MIR377 MIR496 MIR376C MIR1185-1 MIR1185-2
GH14J101096 Enhancer 0.7 FANTOM5 ENCODE 10.9 +42.1 42129 3.2 ATF4 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR412 MIR541 MIR656 MIR410 MIR409 MIR154
GH14J101176 Enhancer 0.5 ENCODE 10.7 +121.1 121147 2 ZNF680 ZFP3 RCOR1 CHD2 MIR154 MIR377 MIR496 MIR134 MIR323B MIR485 MIR487A SNORD113-2 SNORD113-3 ENSG00000222185
GH14J101008 Enhancer 0.2 ENCODE 11 -47.5 -47520 0.2 MIR487A MIR134 MIR323B MIR485 MIR154 MIR377 MIR496 MIR1185-1 MIR300 MIR376C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR323B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR323B Gene

Genomic Locations for MIR323B Gene
82 bases
Plus strand
82 bases
Plus strand

Genomic View for MIR323B Gene

Genes around MIR323B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR323B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR323B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR323B Gene

Proteins for MIR323B Gene

Post-translational modifications for MIR323B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR323B Gene

Domains & Families for MIR323B Gene

Gene Families for MIR323B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR323B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR323B Gene

Function for MIR323B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR323B Gene

Localization for MIR323B Gene

Gene Ontology (GO) - Cellular Components for MIR323B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR323B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR323B Gene

Pathways & Interactions for MIR323B Gene

SuperPathways for MIR323B Gene

No Data Available

Interacting Proteins for MIR323B Gene

Gene Ontology (GO) - Biological Process for MIR323B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR323B Gene

Drugs & Compounds for MIR323B Gene

No Compound Related Data Available

Transcripts for MIR323B Gene

mRNA/cDNA for MIR323B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR323B Gene

No ASD Table

Relevant External Links for MIR323B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR323B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR323B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR323B Gene:

genes like me logo Genes that share expression patterns with MIR323B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR323B Gene

Orthologs for MIR323B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR323B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 100 (a)
(Canis familiaris)
Mammalia -- 34
  • 76 (a)
(Bos Taurus)
Mammalia -- 34
  • 59 (a)
Species where no ortholog for MIR323B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR323B Gene

Gene Tree for MIR323B (if available)
Gene Tree for MIR323B (if available)

Paralogs for MIR323B Gene

No data available for Paralogs for MIR323B Gene

Variants for MIR323B Gene

Sequence variations from dbSNP and Humsavar for MIR323B Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000537528 -- 101,056,105(+) G/T upstream_transcript_variant
rs1002358672 -- 101,056,135(+) G/A upstream_transcript_variant
rs1003488050 -- 101,054,234(+) G/A upstream_transcript_variant
rs1003864116 -- 101,054,505(+) G/T upstream_transcript_variant
rs1005576245 -- 101,055,284(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR323B Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR323B Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR323B Gene

Disorders for MIR323B Gene

Additional Disease Information for MIR323B

No disorders were found for MIR323B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR323B Gene

Publications for MIR323B Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. Association of a microRNA-323b polymorphism with the persistence of hepatitis B virus infection by the enhancement of viral replication. (PMID: 24341744) Yu SJ … Kim YJ (Journal of viral hepatitis 2014) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58

Products for MIR323B Gene

Sources for MIR323B Gene

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