microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR320E Gene

Subcategory (RNA class) for MIR320E Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR320E Gene

  • MicroRNA 320e 2 3 5
  • Hsa-Mir-320e 2 3
  • Hsa-MiR-320e 163 173
  • MIR320E 2 5
  • MIMAT0015072 50
  • MI0014234 50
  • Mir-320e 3
  • RF00736 168

External Ids for MIR320E Gene

Previous GeneCards Identifiers for MIR320E Gene

  • GC19U901374
  • GC19M043637
  • GC19M047213

Summaries for MIR320E Gene

Entrez Gene Summary for MIR320E Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320E Gene

MIR320E (MicroRNA 320e) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR320E Gene

Additional gene information for MIR320E Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR320E Gene

Genomics for MIR320E Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR320E Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J046710 Enhancer 0.4 ENCODE 600.7 -1.4 -1409 0.2 POLR2A TAF1 TBP MIR320E lnc-STRN4-2 PRKD2 DACT3
GH19J046764 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.2 -55.7 -55674 1.1 GATAD2A RCOR2 RXRB CEBPA SOX13 RFX3 CEBPB RFX1 ZBTB26 ZKSCAN8 STRN4 SLC1A5 PRKD2 MIR320E GNG8 TMEM160 ARHGAP35 FKRP RF00017-3026 RF00017-3027
GH19J046733 Promoter/Enhancer 0.9 Ensembl ENCODE 12.2 -24.3 -24327 0.9 JUND SCRT2 FOSL1 CTCF FOSL2 DPF2 FOXA1 ATF3 FOS ZBTB33 lnc-PRKD2-2 STRN4 MIR320E GNG8 ENSG00000222614 FKRP LOC107987269
GH19J046767 Enhancer 1 Ensembl dbSUPER 11.2 -57.4 -57441 0.4 CTCF PRDM10 IKZF1 KDM1A ZNF143 MTA1 PATZ1 ZNF501 ZNF24 TRIM22 STRN4 SLC1A5 IRF2BP1 PRKD2 MIR320E GNG8 TMEM160 ARHGAP35 RF00017-3026 RF00017-3027
GH19J046759 Enhancer 1 Ensembl ENCODE 11.2 -51.7 -51680 4.1 TFE3 NFKBIZ RXRB IRF2 SP1 MNT SOX13 CEBPB MGA EGR1 RF00017-3026 STRN4 SLC1A5 PRKD2 MIR320E AP2S1 GNG8 ARHGAP35 TMEM160 FKRP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR320E on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR320E Gene

Genomic Locations for MIR320E Gene
chr19:46,709,278-46,709,360
(GRCh38/hg38)
Size:
83 bases
Orientation:
Minus strand
chr19:47,212,550-47,212,602
(GRCh37/hg19)
Size:
53 bases
Orientation:
Minus strand

Genomic View for MIR320E Gene

Genes around MIR320E on UCSC Golden Path with GeneCards custom track
MIR320E in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR320E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320E Gene

Proteins for MIR320E Gene

Post-translational modifications for MIR320E Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320E Gene

Domains & Families for MIR320E Gene

Gene Families for MIR320E Gene

genes like me logo Genes that share domains with MIR320E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR320E Gene

Function for MIR320E Gene

Phenotypes From GWAS Catalog for MIR320E Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320E Gene

Localization for MIR320E Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR320E gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
nucleus 1
endosome 1

Gene Ontology (GO) - Cellular Components for MIR320E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR320E: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR320E Gene

Pathways & Interactions for MIR320E Gene

PathCards logo

SuperPathways for MIR320E Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR320E Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR320E: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR320E Gene

Drugs & Compounds for MIR320E Gene

No Compound Related Data Available

Transcripts for MIR320E Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR320E Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00003B6B84_9606 miRNA 18 5

RefSeq: NR_036157,

LncBase: hsa-miR-320e,

miRBase: MIMAT0015072,

TarBase: hsa-miR-320e,

ENA: LM381684.1:1..18:ncRNA, LM611047.1:35..52:ncRNA,

URS0000D55CCB_9606 precursor_RNA 73 3

HGNC: 38230,

RefSeq: NR_036157,

miRBase: MI0014234,

URS000075E854_9606 precursor_RNA 53 2

Ensembl: ENST00000390179 (view in UCSC) ,

ENA: LM611047.1:1..53:precursor_RNA,

URS0000651BC7_9606 precursor_RNA 83 1

Rfam: RF00736,

MIR320E in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR320E Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320E Gene

No ASD Table

Relevant External Links for MIR320E Gene

GeneLoc Exon Structure for
MIR320E

Expression for MIR320E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR320E Gene

genes like me logo Genes that share expression patterns with MIR320E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320E Gene

Orthologs for MIR320E Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320E Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320e 31
  • 100 (a)
OneToOne
Species where no ortholog for MIR320E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR320E Gene

ENSEMBL:
Gene Tree for MIR320E (if available)
TreeFam:
Gene Tree for MIR320E (if available)

Paralogs for MIR320E Gene

No data available for Paralogs for MIR320E Gene

Variants for MIR320E Gene

Additional dbSNP identifiers (rs#s) for MIR320E Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR320E Gene

Variant ID Type Subtype PubMed ID
nsv833850 CNV loss 17160897

Additional Variant Information for MIR320E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR320E Gene

Disorders for MIR320E Gene

No disorders were found for MIR320E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320E Gene

Publications for MIR320E Gene

  1. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  2. MiR-320e is a novel prognostic biomarker in colorectal cancer. (PMID: 26035698) Perez-Carbonell L … Goel A (British journal of cancer 2015) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3

Products for MIR320E Gene

Sources for MIR320E Gene