microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR320D1 Gene

Subcategory (RNA class) for MIR320D1 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR320D1 Gene

  • MicroRNA 320d-1 2 3 5
  • Hsa-Mir-320d-1 2 3
  • Hsa-MiR-320d 163 173
  • MIR320D1 2 5
  • MIMAT0006764 50
  • Mir-320d-1 3
  • MIR320D-1 3
  • MIRN320D1 3
  • MI0008190 50

External Ids for MIR320D1 Gene

Previous HGNC Symbols for MIR320D1 Gene

  • MIRN320D1

Previous GeneCards Identifiers for MIR320D1 Gene

  • GC00U922884
  • GC13M040200
  • GC13M041301

Summaries for MIR320D1 Gene

Entrez Gene Summary for MIR320D1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320D1 Gene

MIR320D1 (MicroRNA 320d-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR320D1 include Panhypopituitarism, X-Linked.

Rfam classification for MIR320D1 Gene

Additional gene information for MIR320D1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR320D1 Gene

Genomics for MIR320D1 Gene

Genomic Locations for MIR320D1 Gene

Genomic Locations for MIR320D1 Gene
chr13:40,727,816-40,727,887
(GRCh38/hg38)
Size:
72 bases
Orientation:
Minus strand
chr13:41,301,964-41,302,011
(GRCh37/hg19)
Size:
48 bases
Orientation:
Minus strand

Genomic View for MIR320D1 Gene

Genes around MIR320D1 on UCSC Golden Path with GeneCards custom track
MIR320D1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR320D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320D1 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR320D1 Gene

Proteins for MIR320D1 Gene

Post-translational modifications for MIR320D1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320D1 Gene

Domains & Families for MIR320D1 Gene

Gene Families for MIR320D1 Gene

genes like me logo Genes that share domains with MIR320D1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR320D1 Gene

Function for MIR320D1 Gene

Phenotypes From GWAS Catalog for MIR320D1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320D1 Gene

Localization for MIR320D1 Gene

Gene Ontology (GO) - Cellular Components for MIR320D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR320D1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR320D1 Gene

Pathways & Interactions for MIR320D1 Gene

PathCards logo

SuperPathways for MIR320D1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR320D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR320D1: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR320D1 Gene

Drugs & Compounds for MIR320D1 Gene

No Compound Related Data Available

Transcripts for MIR320D1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR320D1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000010C72_9606 miRNA 19 5

RefSeq: NR_031723, NR_031725,

LncBase: hsa-miR-320d,

miRBase: MIMAT0006764,

TarBase: hsa-miR-320d,

ENA: LM380895.1:1..19:ncRNA, LM610363.1:30..48:ncRNA, LM610365.1:30..48:ncRNA,

URS0000D561AB_9606 precursor_RNA 72 3

HGNC: 35386,

RefSeq: NR_031723,

miRBase: MI0008190,

URS000075B796_9606 precursor_RNA 48 2

Ensembl: ENST00000390157 (view in UCSC) ,

ENA: LM610363.1:1..48:precursor_RNA,

MIR320D1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR320D1 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320D1 Gene

No ASD Table

Relevant External Links for MIR320D1 Gene

GeneLoc Exon Structure for
MIR320D1

Expression for MIR320D1 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320D1 Gene

Orthologs for MIR320D1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320D1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320d-1 31
  • 100 (a)
OneToOne
Species where no ortholog for MIR320D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR320D1 Gene

ENSEMBL:
Gene Tree for MIR320D1 (if available)
TreeFam:
Gene Tree for MIR320D1 (if available)

Paralogs for MIR320D1 Gene

No data available for Paralogs for MIR320D1 Gene

Variants for MIR320D1 Gene

Additional dbSNP identifiers (rs#s) for MIR320D1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR320D1 Gene

Variant ID Type Subtype PubMed ID
esv3892332 CNV gain 25118596
nsv974239 CNV duplication 23825009

Additional Variant Information for MIR320D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR320D1 Gene

Disorders for MIR320D1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR320D1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
panhypopituitarism, x-linked
  • phpx
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR320D1

genes like me logo Genes that share disorders with MIR320D1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR320D1 Gene

Publications for MIR320D1 Gene

  1. CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma. (PMID: 31059102) Su H … Wang J (Oncology reports 2019) 3
  2. Tumor-derived exosomal miRNA-320d as a biomarker for metastatic colorectal cancer. (PMID: 31420913) Tang Y … Xie L (Journal of clinical laboratory analysis 2019) 3
  3. hsa-miR-320d and hsa-miR-582, miRNA Biomarkers of Aortic Dissection, Regulate Apoptosis of Vascular Smooth Muscle Cells. (PMID: 29538087) Shen H … Shu X (Journal of cardiovascular pharmacology 2018) 3
  4. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  5. Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone. (PMID: 24931464) Wu PY … Wang JF (Human pathology 2014) 3

Products for MIR320D1 Gene

Sources for MIR320D1 Gene