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Aliases for MIR320B1 Gene

Subcategory (RNA class) for MIR320B1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR320B1 Gene

  • MicroRNA 320b-1 2 3 5
  • Hsa-Mir-320b-1 3
  • Mir-320b-1 3
  • MIR320B-1 3
  • MIRN320B1 3

External Ids for MIR320B1 Gene

Previous HGNC Symbols for MIR320B1 Gene

  • MIRN320B1

Previous GeneCards Identifiers for MIR320B1 Gene

  • GC00U922991
  • GC01P117016
  • GC01P117214

Summaries for MIR320B1 Gene

Entrez Gene Summary for MIR320B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320B1 Gene

MIR320B1 (MicroRNA 320b-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR320B1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320B1 Gene

Genomics for MIR320B1 Gene

GeneHancer (GH) Regulatory Elements for MIR320B1 Gene

Promoters and enhancers for MIR320B1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I116671 Enhancer 0.9 ENCODE 550.8 +1.9 1890 3.6 HDGF NFIB ARNT NEUROD1 ZBTB40 RAD21 CBX5 EGR1 ZSCAN5C SCRT2 MIR320B1 ATP1A1-AS1 IGSF3 C1orf137
GH01I116880 Enhancer 1.4 FANTOM5 Ensembl ENCODE 10.6 +210.1 210058 2.5 HDGF PKNOX1 ATF1 ARNT IRF4 TCF12 ZNF766 ARID2 ZNF143 FOS LOC105378927 PTGFRN IGSF3 MIR320B1 CD101 FTH1P22
GH01I116823 Enhancer 1.5 Ensembl ENCODE dbSUPER 9.8 +154.4 154449 4.9 HDGF PKNOX1 SMAD1 ARNT FEZF1 ZNF2 IRF4 POLR2B ZNF766 ZNF207 ATP1A1-AS1 MAN1A2 IGSF3 CD2 PTGFRN MIR320B1 FTH1P22 LOC105378927
GH01I116852 Enhancer 1.4 Ensembl ENCODE dbSUPER 9.9 +182.9 182941 5 PKNOX1 CLOCK FOXA2 NEUROD1 SIN3A FEZF1 ZNF2 ZNF213 ZNF207 FOS PTGFRN CD2 MIR320B1 IGSF3 CD101 LOC105378927 FTH1P22
GH01I116588 Enhancer 1.2 FANTOM5 Ensembl ENCODE 10.9 -81.8 -81844 2.2 ESRRA NFIB NEUROD1 HIC1 CTBP1 ZNF366 ZBTB48 SCRT2 FOSL2 FOS LOC105378924 IGSF3 MIR320B1 CD58 ATP1A1 CD101
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR320B1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR320B1 Gene

Genomic Locations for MIR320B1 Gene
chr1:116,671,749-116,671,827
(GRCh38/hg38)
Size:
79 bases
Orientation:
Plus strand
chr1:117,214,371-117,214,449
(GRCh37/hg19)

Genomic View for MIR320B1 Gene

Genes around MIR320B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320B1 Gene

Proteins for MIR320B1 Gene

Post-translational modifications for MIR320B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320B1 Gene

Domains & Families for MIR320B1 Gene

Gene Families for MIR320B1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320B1 Gene

Function for MIR320B1 Gene

Phenotypes From GWAS Catalog for MIR320B1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320B1 Gene

Localization for MIR320B1 Gene

Gene Ontology (GO) - Cellular Components for MIR320B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR320B1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR320B1 Gene

Pathways & Interactions for MIR320B1 Gene

SuperPathways for MIR320B1 Gene

No Data Available

Interacting Proteins for MIR320B1 Gene

Gene Ontology (GO) - Biological Process for MIR320B1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320B1 Gene

Drugs & Compounds for MIR320B1 Gene

No Compound Related Data Available

Transcripts for MIR320B1 Gene

mRNA/cDNA for MIR320B1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320B1 Gene

No ASD Table

Relevant External Links for MIR320B1 Gene

GeneLoc Exon Structure for
MIR320B1
ECgene alternative splicing isoforms for
MIR320B1

Expression for MIR320B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320B1 Gene:

MIR320B1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320B1 Gene

Orthologs for MIR320B1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320b-1 34
  • 100 (a)
OneToOne
Species where no ortholog for MIR320B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320B1 Gene

ENSEMBL:
Gene Tree for MIR320B1 (if available)
TreeFam:
Gene Tree for MIR320B1 (if available)

Paralogs for MIR320B1 Gene

No data available for Paralogs for MIR320B1 Gene

Variants for MIR320B1 Gene

Sequence variations from dbSNP and Humsavar for MIR320B1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000613063 -- 116,670,815(+) G/T upstream_transcript_variant
rs1001709135 -- 116,672,079(+) T/A downstream_transcript_variant
rs1002607128 -- 116,670,105(+) G/A upstream_transcript_variant
rs1002723471 -- 116,670,522(+) TAT/T upstream_transcript_variant
rs1004232191 -- 116,671,282(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR320B1 Gene

Variant ID Type Subtype PubMed ID
nsv831148 CNV gain 17160897
nsv428190 CNV gain 18775914
esv2758963 CNV gain+loss 17122850

Additional Variant Information for MIR320B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320B1 Gene

Disorders for MIR320B1 Gene

Additional Disease Information for MIR320B1

No disorders were found for MIR320B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320B1 Gene

Publications for MIR320B1 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma. (PMID: 27428374) Li Y … Ma J (PLoS genetics 2016) 3 58
  3. Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia. (PMID: 25428891) Kubiczkova Besse L … Sevcikova S (American journal of hematology 2015) 3 58
  4. MicroRNA-320b promotes colorectal cancer proliferation and invasion by competing with its homologous microRNA-320a. (PMID: 25458952) Zhou J … Zheng S (Cancer letters 2015) 3 58
  5. Platelet-derived growth factor-BB enhances MSC-mediated cardioprotection via suppression of miR-320 expression. (PMID: 25724494) Xu B … Wang Y (American journal of physiology. Heart and circulatory physiology 2015) 3 58

Products for MIR320B1 Gene

Sources for MIR320B1 Gene

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