microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3200 Gene

Subcategory (RNA class) for MIR3200 Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR3200 Gene

  • MicroRNA 3200 2 3 5
  • Hsa-Mir-3200 2 3 178
  • Hsa-MiR-3200-3p 163 173
  • Hsa-MiR-3200-5p 163 173
  • MIR3200 2 5
  • MIMAT0015085 50
  • MIMAT0017392 50
  • MI0014249 50
  • Mir-3200 3

External Ids for MIR3200 Gene

Previous GeneCards Identifiers for MIR3200 Gene

  • GC22U900683
  • GC22P031127

Summaries for MIR3200 Gene

Entrez Gene Summary for MIR3200 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3200 Gene

MIR3200 (MicroRNA 3200) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3200 include Lymphoid Interstitial Pneumonia and Orofacial Cleft. Among its related pathways are Alzheimers Disease.

Additional gene information for MIR3200 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3200 Gene

Genomics for MIR3200 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3200 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J030733 Enhancer 0.6 Ensembl ENCODE 600.7 +0.9 944 4.2 JUND CEBPB JUN CTCF MIR3200 SLC35E4 DUSP18 MORC2 SEC14L6 piR-41306-171 OSBP2
GH22J030728 Enhancer 0.8 Ensembl 0.7 -2.6 -2556 2 LEF1 DPF2 HDAC1 SOX6 TCF12 EP300 ZNF766 NFE2 FOXK2 ZNF316 OSBP2 MORC2 MIR3200 lnc-SLC35E4-1
GH22J030716 Enhancer 1.1 FANTOM5 Ensembl ENCODE 0.4 -12.9 -12856 5 ZNF692 ZSCAN4 IKZF2 HDAC1 HMBOX1 EGR1 CTBP1 USF1 MYNN IKZF1 OSBP2 SLC35E4 DUSP18 MIR3200 lnc-SLC35E4-1 MORC2
GH22J030709 Enhancer 0.3 Ensembl 0.4 -21.5 -21456 0.6 NR2F1 OSBP2 SEC14L6 lnc-SLC35E4-1 MIR3200 MORC2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3200 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3200 Gene

Genomic Locations for MIR3200 Gene
chr22:30,731,557-30,731,641
(GRCh38/hg38)
Size:
85 bases
Orientation:
Plus strand
chr22:31,127,544-31,127,628
(GRCh37/hg19)
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR3200 Gene

Genes around MIR3200 on UCSC Golden Path with GeneCards custom track
MIR3200 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3200 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3200 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3200 Gene

Proteins for MIR3200 Gene

Post-translational modifications for MIR3200 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3200 Gene

Domains & Families for MIR3200 Gene

Gene Families for MIR3200 Gene

HGNC:
genes like me logo Genes that share domains with MIR3200: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3200 Gene

Function for MIR3200 Gene

Phenotypes From GWAS Catalog for MIR3200 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3200 Gene

Localization for MIR3200 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3200 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3200 Gene

Pathways & Interactions for MIR3200 Gene

PathCards logo

SuperPathways for MIR3200 Gene

SuperPathway Contained pathways
1 Alzheimers Disease
genes like me logo Genes that share pathways with MIR3200: view

Pathways by source for MIR3200 Gene

1 BioSystems pathway for MIR3200 Gene

Gene Ontology (GO) - Biological Process for MIR3200 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3200 Gene

Drugs & Compounds for MIR3200 Gene

No Compound Related Data Available

Transcripts for MIR3200 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3200 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CE96_9606 precursor_RNA 85 5

HGNC: 38227,

RefSeq: NR_036171,

Ensembl: ENST00000580767 (view in UCSC) ,

miRBase: MI0014249,

ENA: LM611059.1:1..85:precursor_RNA,

URS00001938D9_9606 miRNA 22 5

RefSeq: NR_036171,

LncBase: hsa-miR-3200-5p,

miRBase: MIMAT0017392,

TarBase: hsa-miR-3200-5p,

ENA: LM382027.1:1..22:ncRNA, LM611059.1:13..34:ncRNA,

URS0000381B86_9606 miRNA 22 5

RefSeq: NR_036171,

LncBase: hsa-miR-3200-3p,

miRBase: MIMAT0015085,

TarBase: hsa-miR-3200-3p,

ENA: LM381693.1:1..22:ncRNA, LM611059.1:54..75:ncRNA,

URS000000CFDB_9606 miRNA 23 2

MirGeneDB: Hsa-Mir-3200_3p,

ENA: AB372725.1:1..23:ncRNA, FR772781.1:1..23:ncRNA,

URS00004A4659_9606 miRNA 23 2

MirGeneDB: Hsa-Mir-3200_5p,

ENA: FR772782.1:1..23:ncRNA,

MIR3200 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3200 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3200 Gene

No ASD Table

Relevant External Links for MIR3200 Gene

GeneLoc Exon Structure for
MIR3200

Expression for MIR3200 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3200 Gene

genes like me logo Genes that share expression patterns with MIR3200: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3200 Gene

Orthologs for MIR3200 Gene

Evolution for MIR3200 Gene

ENSEMBL:
Gene Tree for MIR3200 (if available)
TreeFam:
Gene Tree for MIR3200 (if available)

No data available for Orthologs for MIR3200 Gene

Paralogs for MIR3200 Gene

No data available for Paralogs for MIR3200 Gene

Variants for MIR3200 Gene

Additional dbSNP identifiers (rs#s) for MIR3200 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3200 Gene

Variant ID Type Subtype PubMed ID
nsv1110864 OTHER inversion 24896259

Additional Variant Information for MIR3200 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3200

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3200 Gene

Disorders for MIR3200 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR3200 Gene - From: DISEASES

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3200

genes like me logo Genes that share disorders with MIR3200: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3200 Gene

Publications for MIR3200 Gene

  1. MicroRNA-3200-5p Promotes Osteosarcoma Cell Invasion via Suppression of BRMS1. (PMID: 29890825) Li G … Cai M (Molecules and cells 2018) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3

Products for MIR3200 Gene

Sources for MIR3200 Gene