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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR3199-2 Gene
Data sources for MIR3199-2 Gene:
Subcategory (RNA class) for MIR3199-2 Gene
miRNA
Aliases for MIR3199-2 Gene
- MicroRNA 3199-2 (HGNC, NCBI Entrez Gene, Ensembl)
- Hsa-Mir-3199-2 (HGNC, NCBI Entrez Gene)
- Hsa-MiR-3199 (LncBase, TarBase)
- MIMAT0015084 (miRBase)
- Mir-3199-2 (NCBI Entrez Gene)
- MIR3199-2 (Ensembl)
- MI0014248 (miRBase)
External Ids for MIR3199-2 Gene
- HGNC: 38205
- NCBI Entrez Gene: 100422998
- Ensembl: ENSG00000283225
- miRBase: hsa-mir-3199-2
Previous GeneCards Identifiers for MIR3199-2 Gene
- GC22U900724
- GC22P028319
- GC22P028322
- GC22P028326
Summaries for MIR3199-2 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR3199-2 Gene
MIR3199-2 (MicroRNA 3199-2) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR3199-2 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3199-2 Gene
Genomics for MIR3199-2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR3199-2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH22J027917 | Promoter/Enhancer | 2.4 | EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas | 0.7 | -2.2 | -2177 | 5.5 | TBP MXD4 MNT IKZF1 SMAD5 MBD2 POLR2A BHLHE40 ELF1 ZIC2 | TTC28-AS1 PITPNB ENSG00000277460 lnc-TTC28-2 TTC28 MIR3199-1 MIR3199-2 lnc-TTC28-3 MN1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR3199-2 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR3199-2 Gene
Latest Assembly
- chr22:27,920,526-27,920,611
- (GRCh38/hg38)
- Size:
- 86 bases
- Orientation:
- Plus strand
Previous Assembly
- chr22:28,316,514-28,316,599
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 86 bases
- Orientation:
- Plus strand
Genomic View for MIR3199-2 Gene
Genes around MIR3199-2 on UCSC Golden Path with GeneCards custom track
MIR3199-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 22q12.1 by HGNC
- 22q12.1 by Entrez Gene
- 22q12.1 by Ensembl
MIR3199-2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR3199-2 Gene
Proteins for MIR3199-2 Gene
Post-translational modifications for MIR3199-2 Gene
No Post-translational modifications
No data available for DME Specific Peptides for MIR3199-2 Gene
Domains & Families for MIR3199-2 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3199-2 Gene
Function for MIR3199-2 Gene
Phenotypes From GWAS Catalog for MIR3199-2 Gene
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MIR3199-2 - Starting at $85 >
- * MIR3199-2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
Clone products for research
- Applied Biological Materials (abm): Clones for MIR3199-2 - Starting at $45 >
- * MIR3199-2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3199-2 Gene
Localization for MIR3199-2 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3199-2 Gene
Transcripts for MIR3199-2 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3199-2 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000031362A_9606 | miRNA | 23 | 5 |
LncBase: hsa-miR-3199, miRBase: MIMAT0015084, TarBase: hsa-miR-3199, ENA: LM381692.1:1..23:ncRNA, LM611057.1:10..32:ncRNA, LM611058.1:10..32:ncRNA, |
| URS000075B20A_9606 | precursor_RNA | 86 | 4 |
RefSeq: NR_036170, Ensembl: ENST00000636243 (view in UCSC) , miRBase: MI0014248, |
| URS00002ECC5E_9606 | miRNA | 20 | 1 |
ENA: AB372724.1:1..20:ncRNA, |
MIR3199-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for MIR3199-2 Gene
- 1 NCBI additional mRNA sequence :
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MIR3199-2 - Starting at $85 >
- * MIR3199-2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
Clone products for research
- Applied Biological Materials (abm): Clones for MIR3199-2 - Starting at $45 >
- * MIR3199-2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
Relevant External Links for MIR3199-2 Gene
- GeneLoc Exon Structure for
- MIR3199-2
Expression for MIR3199-2 Gene
Primer products for research
-
OriGene qPCR primer pairs for MIR3199-2
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3199-2 Gene
Orthologs for MIR3199-2 Gene
No data available for Orthologs for MIR3199-2 Gene
Paralogs for MIR3199-2 Gene
No data available for Paralogs for MIR3199-2 Gene
Variants for MIR3199-2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1129409 | OTHER | inversion | 24896259 |
Additional Variant Information for MIR3199-2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR3199-2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3199-2 Gene
Disorders for MIR3199-2 Gene
Additional Disease Information for MIR3199-2
No disorders were found for MIR3199-2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3199-2 Gene
Publications for MIR3199-2 Gene
- hsa-mir-3199-2 and hsa-mir-1293 as Novel Prognostic Biomarkers of Papillary Renal Cell Carcinoma by COX Ratio Risk Regression Model Screening. (PMID: 28338236) Luo W … Wang XX (Journal of cellular biochemistry 2017) 3
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
- Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
Products for MIR3199-2 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3199-2
- Origene Custom Protein Services for MIR3199-2
- Browse OriGene Inhibitory RNA Products For MIR3199-2
- OriGene qPCR primer pairs for MIR3199-2
- Browse CRISPR knockouts for MIR3199-2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR3199-2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR3199-2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR3199-2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR3199-2
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR3199-2
Sources for MIR3199-2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB