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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR3198-1 Gene
Subcategory (RNA class) for MIR3198-1 Gene
miRNA
Number of RNA Genes sources:
3 / 17
Aliases for MIR3198-1 Gene
External Ids for MIR3198-1 Gene
- HGNC: 38236
- Entrez Gene: 100423025
- Ensembl: ENSG00000264757
- miRBase: hsa-mir-3198-1
Previous HGNC Symbols for MIR3198-1 Gene
- MIR3198
Previous GeneCards Identifiers for MIR3198-1 Gene
- GC22M018247
Summaries for MIR3198-1 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR3198-1 Gene
MIR3198-1 (MicroRNA 3198-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3198-1 include Retinitis Pigmentosa 41 and Retinitis Pigmentosa 27.
Additional gene information for MIR3198-1 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3198-1 Gene
Genomics for MIR3198-1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR3198-1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH22J017763 | Enhancer | 0.4 | ENCODE dbSUPER | 600.7 | +0.5 | 490 | 0.9 | HNF4A | MIR3198-1 piR-39622-002 BID hsa-miR-5095-329 BCL2L13 | |
| GH22J017759 | Promoter/Enhancer | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 0.7 | +3.6 | 3557 | 1.5 | GATAD2A JUND SP1 CEBPA SOX13 ZBTB20 TCF7 FOXA2 YY1 FOSL1 | BID CECR2 BCL2L13 USP18 MIR3198-1 hsa-miR-5095-329 | |
| GH22J017751 | Enhancer | 0.9 | Ensembl ENCODE dbSUPER | 0.4 | +10.9 | 10858 | 3.2 | HNRNPL CTCF POLR2A RAD21 ZNF316 SMC3 MAFG RXRA ZNF143 KLF1 | hsa-miR-5095-329 BID BCL2L13 MIR3198-1 | |
| GH22J017761 | Enhancer | 0.5 | dbSUPER | 0.7 | +2.3 | 2250 | 0.6 | CEBPA FOXA2 NFIL3 KDM1A FOXA3 | MIR3198-1 hsa-miR-5095-329 BID BCL2L13 | |
| GH22J017757 | Enhancer | 0.3 | Ensembl dbSUPER | 0.4 | +5.9 | 5858 | 0.4 | MIR3198-1 hsa-miR-5095-329 BID BCL2L13 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR3198-1 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR3198-1 Gene
Genomic Locations for MIR3198-1 Gene
- chr22:17,764,180-17,764,259
- (GRCh38/hg38)
- Size:
- 80 bases
- Orientation:
- Minus strand
- chr22:18,246,946-18,247,025
- (GRCh37/hg19)
- Size:
- 80 bases
- Orientation:
- Minus strand
Genomic View for MIR3198-1 Gene
Genes around MIR3198-1 on UCSC Golden Path with GeneCards custom track
MIR3198-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 22q11.21 by HGNC
- 22q11.21 by Entrez Gene
- 22q11.21 by Ensembl
MIR3198-1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR3198-1 Gene
Proteins for MIR3198-1 Gene
Post-translational modifications for MIR3198-1 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3198-1
- Origene Custom Protein Services for MIR3198-1
No data available for DME Specific Peptides for MIR3198-1 Gene
Domains & Families for MIR3198-1 Gene
Gene Families for MIR3198-1 Gene
- HGNC:
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3198-1 Gene
Function for MIR3198-1 Gene
Phenotypes From GWAS Catalog for MIR3198-1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR3198-1 - Select products 50% OFF >
- * MIR3198-1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR3198-1
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR3198-1 - Select products 50% OFF >
- * MIR3198-1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3198-1 Gene
Localization for MIR3198-1 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3198-1 Gene
Transcripts for MIR3198-1 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3198-1 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000075A8F7_9606 | precursor_RNA | 80 | 5 |
HGNC: 38236, RefSeq: NR_036168, Ensembl: ENST00000583102 (view in UCSC) , miRBase: MI0014246, |
| URS000012568D_9606 | miRNA | 22 | 4 |
miRBase: MIMAT0015083, TarBase: hsa-miR-3198, ENA: FR772780.1:1..22:ncRNA, FR772968.1:1..22:ncRNA, LM381691.1:1..22:ncRNA, LM611056.1:49..70:ncRNA, LM611385.1:49..70:ncRNA, |
MIR3198-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for MIR3198-1 Gene
- 1 NCBI additional mRNA sequence :
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR3198-1 - Select products 50% OFF >
- * MIR3198-1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR3198-1
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR3198-1 - Select products 50% OFF >
- * MIR3198-1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for MIR3198-1 Gene
- GeneLoc Exon Structure for
- MIR3198-1
Expression for MIR3198-1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3198-1
Primer Products
-
OriGene qPCR primer pairs for MIR3198-1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3198-1 Gene
Orthologs for MIR3198-1 Gene
No data available for Orthologs for MIR3198-1 Gene
Paralogs for MIR3198-1 Gene
No data available for Paralogs for MIR3198-1 Gene
Variants for MIR3198-1 Gene
Additional Variant Information for MIR3198-1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR3198-1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3198-1 Gene
Disorders for MIR3198-1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinitis pigmentosa 41 |
|
|
| retinitis pigmentosa 27 |
|
|
| usher syndrome, type ig |
|
|
Search MIR3198-1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MIR3198-1
No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3198-1 Gene
Publications for MIR3198-1 Gene
- Compression and tension variably alter Osteoprotegerin expression via miR-3198 in periodontal ligament cells. (PMID: 31041888) Kanzaki H … Nakamura Y (BMC molecular and cell biology 2019) 3
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
- Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
- Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
Products for MIR3198-1 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3198-1
- Origene Custom Protein Services for MIR3198-1
- Browse OriGene Inhibitory RNA Products For MIR3198-1
- OriGene qPCR primer pairs for MIR3198-1
- Browse CRISPR knockouts for MIR3198-1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR3198-1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR3198-1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR3198-1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR3198-1
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR3198-1
Sources for MIR3198-1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
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- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
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- (122) ENCODE
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- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
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- (128) SNPedia
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- (130) CIViC
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- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
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- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
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- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB