microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3185 Gene

Data sources for MIR3185 Gene:

RNA type for MIR3185 Gene

miRNA

Aliases for MIR3185 Gene

External Ids for MIR3185 Gene

Previous GeneCards Identifiers for MIR3185 Gene

  • GC17U901506
  • GC17M042170
  • GC17M046801

Summaries for MIR3185 Gene

Entrez Gene Summary for MIR3185 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3185 Gene

MIR3185 (MicroRNA 3185) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3185 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3185 Gene

Genomics for MIR3185 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3185 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J048722 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE dbSUPER 250.7 +1.2 1171 3.8 ZNF654 REST TRIM22 CTCF RAD21 SMC3 TCF7L2 CBX8 ELF1 ZBTB33 PRAC2 ENSG00000273750 ENSG00000277542 HSALNG0117116 HSALNG0117117 MIR3185 PRAC1 LRRC46 HOXB13 UBE2Z
GH17J048728 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE dbSUPER 0.7 -4.1 -4126 2.4 EZH2 ZNF654 ZNF600 ZNF580 ATF2 ZSCAN16 NFIC ZIC2 ZBTB10 PLRG1 HOXB13 HSALNG0117118 UBE2Z SP2 ENSG00000264701 CDK5RAP3 SCRN2 ENSG00000266601 CBX1 LOC105371814
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3185 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3185 Gene

Latest Assembly
chr17:48,724,408-48,724,475
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand

Previous Assembly
chr17:46,801,770-46,801,837
(GRCh37/hg19 by Entrez Gene)
Size:
68 bases
Orientation:
Minus strand

chr17:46,801,770-46,801,837
(GRCh37/hg19 by Ensembl)
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR3185 Gene

Genes around MIR3185 on UCSC Golden Path with GeneCards custom track
MIR3185 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3185 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3185 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3185 Gene

Proteins for MIR3185 Gene

Post-translational modifications for MIR3185 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3185 Gene

Domains & Families for MIR3185 Gene

Gene Families for MIR3185 Gene

HGNC:
genes like me logo Genes that share domains with MIR3185: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3185 Gene

Function for MIR3185 Gene

Phenotypes From GWAS Catalog for MIR3185 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3185 Gene

Localization for MIR3185 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3185 Gene

Pathways & Interactions for MIR3185 Gene

PathCards logo

SuperPathways for MIR3185 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3185 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3185 Gene

Drugs & Compounds for MIR3185 Gene

No Compound Related Data Available

Transcripts for MIR3185 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3185 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075AE3A_9606 pre_miRNA 68 3

RefSeq: NR_036150,

Ensembl: ENST00000583892 (view in UCSC) ,

miRBase: MI0014227,

URS0000152381_9606 miRNA 23 2

RefSeq: NR_036150,

miRBase: MIMAT0015065,

MIR3185 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3185 Gene

No ASD Table

Relevant External Links for MIR3185 Gene

GeneLoc Exon Structure for
MIR3185

No data available for mRNA/cDNA for MIR3185 Gene

Expression for MIR3185 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3185 Gene

Orthologs for MIR3185 Gene

Evolution for MIR3185 Gene

ENSEMBL:
Gene Tree for MIR3185 (if available)
TreeFam:
Gene Tree for MIR3185 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3185

No data available for Orthologs for MIR3185 Gene

Paralogs for MIR3185 Gene

No data available for Paralogs for MIR3185 Gene

Variants for MIR3185 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3185 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3185 Gene

Variant ID Type Subtype PubMed ID
esv2758694 CNV gain 17122850

Additional Variant Information for MIR3185 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3185
Leiden Open Variation Database (LOVD)
MIR3185

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3185 Gene

Disorders for MIR3185 Gene

Additional Disease Information for MIR3185

No disorders were found for MIR3185 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3185 Gene

Publications for MIR3185 Gene

  1. Identification of the miRNA-3185/CYP4A11 axis in cardiac tissue as a biomarker for mechanical asphyxia. (PMID: 32320934) Han L … Chen L (Forensic science international 2020) 3
  2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3185 Gene

Sources for MIR3185 Gene