microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3182 Gene

Data sources for MIR3182 Gene:

Subcategory (RNA class) for MIR3182 Gene

miRNA

Aliases for MIR3182 Gene

External Ids for MIR3182 Gene

Previous GeneCards Identifiers for MIR3182 Gene

  • GC16U901251

Summaries for MIR3182 Gene

Entrez Gene Summary for MIR3182 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3182 Gene

MIR3182 (MicroRNA 3182) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3182 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3182 Gene

Genomics for MIR3182 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3182 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J083512 Enhancer 0.6 Ensembl ENCODE 0.7 +5.0 4987 1.3 FOSL1 JUND EP300 FOS MIR3182 HSALNG0113064 HSBP1 CDH13
GH16J083532 Enhancer 0.5 Ensembl 0.3 +24.8 24755 1 ELF1 JUND FOSL2 FOS ZFHX2 MIR3182 HSALNG0113064 HSBP1 CDH13
GH16J083529 Enhancer 0.3 Ensembl ENCODE 0.3 +22.2 22234 1.4 MIR3182 HSALNG0113064 HSBP1 CDH13
GH16J083549 Enhancer 0.4 Ensembl 0.3 +41.9 41855 0.8 ATF4 MEIS2 POLR2A CTCF HSALNG0113064 MIR3182 HSBP1 CDH13
GH16J083552 Enhancer 0.3 Ensembl 0.3 +44.1 44055 0.8 BHLHE40 EP300 HSALNG0113064 MIR3182 HSBP1 CDH13
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3182 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3182 Gene

Latest Assembly
chr16:83,508,346-83,508,408
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand

Previous Assembly
chr16:83,541,951-83,542,013
(GRCh37/hg19 by Entrez Gene)
Size:
63 bases
Orientation:
Plus strand

chr16:83,541,951-83,542,013
(GRCh37/hg19 by Ensembl)
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR3182 Gene

Genes around MIR3182 on UCSC Golden Path with GeneCards custom track
MIR3182 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3182 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3182 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3182 Gene

Proteins for MIR3182 Gene

Post-translational modifications for MIR3182 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3182 Gene

Domains & Families for MIR3182 Gene

Gene Families for MIR3182 Gene

HGNC:
genes like me logo Genes that share domains with MIR3182: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3182 Gene

Function for MIR3182 Gene

Phenotypes From GWAS Catalog for MIR3182 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3182 Gene

Localization for MIR3182 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3182 Gene

Pathways & Interactions for MIR3182 Gene

PathCards logo

SuperPathways for MIR3182 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3182 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3182 Gene

Drugs & Compounds for MIR3182 Gene

No Compound Related Data Available

Transcripts for MIR3182 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3182 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B814_9606 precursor_RNA 63 4

RefSeq: NR_036147,

Ensembl: ENST00000580839 (view in UCSC) ,

miRBase: MI0014224,

ENA: LM611039.1:1..63:precursor_RNA,

URS00002FAA8C_9606 miRNA 17 3

RefSeq: NR_036147,

miRBase: MIMAT0015062,

ENA: LM381677.1:1..17:ncRNA, LM611039.1:4..20:ncRNA,

MIR3182 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3182 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3182 Gene

No ASD Table

Relevant External Links for MIR3182 Gene

GeneLoc Exon Structure for
MIR3182

Expression for MIR3182 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3182 Gene

Orthologs for MIR3182 Gene

Evolution for MIR3182 Gene

ENSEMBL:
Gene Tree for MIR3182 (if available)
TreeFam:
Gene Tree for MIR3182 (if available)

No data available for Orthologs for MIR3182 Gene

Paralogs for MIR3182 Gene

No data available for Paralogs for MIR3182 Gene

Variants for MIR3182 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3182 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3182 Gene

Variant ID Type Subtype PubMed ID
dgv3051n100 CNV gain 25217958
dgv5253n54 CNV gain 21841781
esv2761929 CNV loss 21179565
nsv1061288 CNV gain+loss 25217958
nsv1064977 CNV loss 25217958
nsv573371 CNV loss 21841781
nsv573397 CNV loss 21841781

Additional Variant Information for MIR3182 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3182

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3182 Gene

Disorders for MIR3182 Gene

Additional Disease Information for MIR3182

No disorders were found for MIR3182 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3182 Gene

Publications for MIR3182 Gene

  1. The long noncoding RNA linc00858 promotes progress of lung cancer through miR-3182/MMP2 axis. (PMID: 31131637) Xue M … Wang W (Artificial cells, nanomedicine, and biotechnology 2019) 3
  2. Three miRNAs cooperate with host genes involved in human cardiovascular disease. (PMID: 31464655) Zhu Y … Sun H (Human genomics 2019) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3182 Gene

Sources for MIR3182 Gene