microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3179-1 Gene

Subcategory (RNA class) for MIR3179-1 Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR3179-1 Gene

  • MicroRNA 3179-1 2 3 5
  • Hsa-Mir-3179-1 2 3
  • Hsa-MiR-3179 163 173
  • MIR3179-1 2 5
  • MIMAT0015056 50
  • MI0014216 50
  • MI0014213 50
  • MIR3179-4 2
  • MI0031510 50
  • MIR3179-3 2
  • MI0014221 50
  • MIR3179-2 2
  • RF02021 168

External Ids for MIR3179-1 Gene

Previous GeneCards Identifiers for MIR3179-1 Gene

  • GC16U901220
  • GC16P014995
  • GC16P014902
  • GC16P014905
  • GC16P015040

Summaries for MIR3179-1 Gene

Entrez Gene Summary for MIR3179-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3179-1 Gene

MIR3179-1 (MicroRNA 3179-1) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR3179-1 Gene

Additional gene information for MIR3179-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3179-1 Gene

Genomics for MIR3179-1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3179-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J014901 Enhancer 0.4 Ensembl ENCODE 600.7 +1.1 1093 3.6 ATF4 ENSG00000257264 MIR3179-1 piR-57045-001 LOC101927469 NPIPA1 NOMO1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3179-1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3179-1 Gene

Genomic Locations for MIR3179-1 Gene
chr16:14,901,508-14,901,591
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand
chr16:14,995,356-14,996,031
(GRCh37/hg19)
Size:
676 bases
Orientation:
Plus strand

Genomic View for MIR3179-1 Gene

Genes around MIR3179-1 on UCSC Golden Path with GeneCards custom track
MIR3179-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3179-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3179-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3179-1 Gene

Proteins for MIR3179-1 Gene

Post-translational modifications for MIR3179-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3179-1 Gene

Domains & Families for MIR3179-1 Gene

Gene Families for MIR3179-1 Gene

genes like me logo Genes that share domains with MIR3179-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3179-1 Gene

Function for MIR3179-1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3179-1 Gene

Localization for MIR3179-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3179-1 Gene

Pathways & Interactions for MIR3179-1 Gene

PathCards logo

SuperPathways for MIR3179-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3179-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR3179-1: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3179-1 Gene

Drugs & Compounds for MIR3179-1 Gene

No Compound Related Data Available

Transcripts for MIR3179-1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3179-1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000064A21C_9606 precursor_RNA 84 6

HGNC: 38214, 38325, 38353, 50838,

RefSeq: NR_036140, NR_036143, NR_036145, NR_128709,

Ensembl: ENST00000578940 (view in UCSC) , ENST00000579107 (view in UCSC) , ENST00000579566 (view in UCSC) , ENST00000617599 (view in UCSC) ,

miRBase: MI0014213, MI0014216, MI0014221, MI0031510,

Rfam: RF02021,

ENA: LM611032.1:1..84:precursor_RNA, LM611035.1:1..84:precursor_RNA, LM611037.1:1..84:precursor_RNA, LM611888.1:1..84:precursor_RNA,

URS00003AF4CD_9606 miRNA 22 5

RefSeq: NR_036140, NR_036143, NR_036145, NR_128709,

LncBase: hsa-miR-3179,

miRBase: MIMAT0015056,

TarBase: hsa-miR-3179,

ENA: View 8 records in RNAcentral

MIR3179-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3179-1 Gene

No ASD Table

Relevant External Links for MIR3179-1 Gene

GeneLoc Exon Structure for
MIR3179-1

No data available for mRNA/cDNA for MIR3179-1 Gene

Expression for MIR3179-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3179-1 Gene

genes like me logo Genes that share expression patterns with MIR3179-1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3179-1 Gene

Orthologs for MIR3179-1 Gene

Evolution for MIR3179-1 Gene

ENSEMBL:
Gene Tree for MIR3179-1 (if available)
TreeFam:
Gene Tree for MIR3179-1 (if available)

No data available for Orthologs for MIR3179-1 Gene

Paralogs for MIR3179-1 Gene

No data available for Paralogs for MIR3179-1 Gene

Variants for MIR3179-1 Gene

Additional dbSNP identifiers (rs#s) for MIR3179-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3179-1 Gene

Variant ID Type Subtype PubMed ID
dgv111n111 CNV duplication 26073780
dgv112n111 CNV duplication 26073780
dgv2738n100 CNV gain 25217958
dgv2740n100 CNV loss 25217958
dgv2741n100 CNV gain+loss 25217958
dgv2742n100 CNV gain 25217958
dgv2744n100 CNV loss 25217958
dgv2745n100 CNV gain 25217958
dgv2746n100 CNV gain+loss 25217958
dgv2747n100 CNV loss 25217958
dgv2749n100 CNV gain 25217958
dgv2750n100 CNV loss 25217958
dgv2751n100 CNV gain 25217958
dgv2752n100 CNV gain+loss 25217958
dgv2753n100 CNV loss 25217958
dgv2754n100 CNV loss 25217958
dgv2755n100 CNV gain 25217958
dgv2756n100 CNV loss 25217958
dgv2757n100 CNV gain+loss 25217958
dgv2775n100 CNV gain 25217958
dgv2776n100 CNV gain+loss 25217958
dgv2777n100 CNV loss 25217958
dgv2781n100 CNV gain+loss 25217958
dgv2782n100 CNV loss 25217958
dgv2783n100 CNV gain 25217958
dgv2784n100 CNV gain 25217958
dgv2n1 OTHER inversion 15895083
dgv4924n54 CNV gain 21841781
dgv791e212 CNV loss 25503493
esv22206 CNV gain+loss 19812545
esv2714015 CNV deletion 23290073
esv2751550 CNV gain 17911159
esv2758632 CNV gain+loss 17122850
esv2758633 CNV gain+loss 17122850
esv2758634 CNV gain+loss 17122850
esv2760416 CNV gain+loss 21179565
esv2762254 CNV gain+loss 21179565
esv2762276 CNV gain+loss 21179565
esv28069 CNV gain+loss 19812545
esv28183 CNV gain+loss 19812545
esv32598 CNV gain 17666407
esv33614 CNV gain+loss 17666407
esv3414503 CNV duplication 20981092
esv34419 CNV gain 17911159
esv3570331 CNV gain 25503493
esv3570398 CNV gain 25503493
esv3582069 CNV loss 25503493
esv3584701 CNV loss 24956385
esv990950 CNV gain 20482838
esv994412 CNV gain 20482838
nsv1038955 CNV loss 25217958
nsv1043239 CNV gain 25217958
nsv1047898 CNV loss 25217958
nsv1048002 CNV gain 25217958
nsv1049647 CNV gain+loss 25217958
nsv1075912 CNV duplication 25765185
nsv1076420 CNV duplication 25765185
nsv1077817 CNV duplication 25765185
nsv1110264 CNV duplication 24896259
nsv1110270 CNV duplication 24896259
nsv1124728 CNV duplication 24896259
nsv1125134 CNV deletion 24896259
nsv1141278 CNV duplication 24896259
nsv1147165 CNV duplication 26484159
nsv1151549 CNV duplication 26484159
nsv1152913 CNV duplication 26484159
nsv1160344 CNV deletion 26073780
nsv1160345 CNV duplication 26073780
nsv1160346 CNV duplication 26073780
nsv1160365 CNV duplication 26073780
nsv136 OTHER inversion 15895083
nsv428319 CNV loss 18775914
nsv428320 CNV loss 18775914
nsv433435 CNV gain 18776910
nsv435664 CNV deletion 17901297
nsv442710 CNV gain 18776908
nsv457428 CNV gain 19166990
nsv499081 OTHER inversion 21111241
nsv509599 CNV insertion 20534489
nsv509601 CNV insertion 20534489
nsv511045 OTHER complex 20534489
nsv7277 OTHER inversion 18451855
nsv7278 OTHER inversion 18451855
nsv820784 CNV deletion 20802225
nsv833160 CNV gain 17160897
nsv9355 CNV gain+loss 18304495
nsv9363 CNV loss 18304495
nsv9378 CNV gain+loss 18304495
nsv952929 CNV duplication 24416366
nsv974762 CNV duplication 23825009
nsv977930 CNV duplication 23825009
nsv978101 CNV duplication 23825009

Additional Variant Information for MIR3179-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3179-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3179-1 Gene

Disorders for MIR3179-1 Gene

Additional Disease Information for MIR3179-1

No disorders were found for MIR3179-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3179-1 Gene

Publications for MIR3179-1 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  3. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3179-1 Gene

Sources for MIR3179-1 Gene