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Aliases for MIR3177 Gene

Subcategory (RNA class) for MIR3177 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3177 Gene

  • MicroRNA 3177 2 3 5
  • Hsa-Mir-3177 3
  • Mir-3177 3

External Ids for MIR3177 Gene

Previous GeneCards Identifiers for MIR3177 Gene

  • GC16U901235
  • GC16P001784

Summaries for MIR3177 Gene

Entrez Gene Summary for MIR3177 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3177 Gene

MIR3177 (MicroRNA 3177) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3177 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3177 Gene

Genomics for MIR3177 Gene

GeneHancer (GH) Regulatory Elements for MIR3177 Gene

Promoters and enhancers for MIR3177 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I001720 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 -12.4 -12371 3.4 ZNF2 ZBTB7B IRF4 SLC30A9 ZNF121 ZNF143 ZNF548 FOS RUNX3 DEK ENSG00000261505 TELO2 SNORA64 ENSG00000260954 ENSG00000260051 ENSG00000255513 CRAMP1 UBE2I UNKL E4F1
GH16I001718 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 -15.6 -15619 2.6 ELF3 FOXA2 NFIB ARID4B ZSCAN9 RARA ZSCAN5C FOS RCOR1 RUNX3 TMEM204 TELO2 LOC101929480 MAPK8IP3 LOC105379547 MIR3177
GH16I001744 Enhancer 0.8 Ensembl ENCODE 0.4 +11.3 11251 2.8 STAT1 MAZ USF1 JUN CEBPB MNT JUND POLR2A STAT3 SMC3 HAGH MAPK8IP3 JPT2 RPS3AP2 CLCN7 ENSG00000261207 GC16P001748 MIR3177
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3177 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3177 Gene

Genomic Locations for MIR3177 Gene
chr16:1,734,985-1,735,066
(GRCh38/hg38)
Size:
82 bases
Orientation:
Plus strand
chr16:1,784,986-1,785,067
(GRCh37/hg19)

Genomic View for MIR3177 Gene

Genes around MIR3177 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3177 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3177 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3177 Gene

Proteins for MIR3177 Gene

Post-translational modifications for MIR3177 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3177 Gene

Domains & Families for MIR3177 Gene

Gene Families for MIR3177 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3177: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3177 Gene

Function for MIR3177 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3177 Gene

Localization for MIR3177 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3177 Gene

Pathways & Interactions for MIR3177 Gene

SuperPathways for MIR3177 Gene

No Data Available

Interacting Proteins for MIR3177 Gene

Gene Ontology (GO) - Biological Process for MIR3177 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3177 Gene

Drugs & Compounds for MIR3177 Gene

No Compound Related Data Available

Transcripts for MIR3177 Gene

mRNA/cDNA for MIR3177 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3177 Gene

No ASD Table

Relevant External Links for MIR3177 Gene

GeneLoc Exon Structure for
MIR3177
ECgene alternative splicing isoforms for
MIR3177

Expression for MIR3177 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3177 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3177 Gene:

MIR3177
genes like me logo Genes that share expression patterns with MIR3177: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3177 Gene

Orthologs for MIR3177 Gene

Evolution for MIR3177 Gene

ENSEMBL:
Gene Tree for MIR3177 (if available)
TreeFam:
Gene Tree for MIR3177 (if available)

No data available for Orthologs for MIR3177 Gene

Paralogs for MIR3177 Gene

No data available for Paralogs for MIR3177 Gene

Variants for MIR3177 Gene

Sequence variations from dbSNP and Humsavar for MIR3177 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000659364 -- 1,733,657(+) G/A upstream_transcript_variant
rs1001409044 -- 1,733,503(+) C/T upstream_transcript_variant
rs1001443974 -- 1,733,217(+) G/A upstream_transcript_variant
rs1003440950 -- 1,734,763(+) A/G upstream_transcript_variant
rs1004130238 -- 1,735,217(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3177 Gene

Variant ID Type Subtype PubMed ID
nsv952900 CNV deletion 24416366
nsv571169 CNV loss 21841781
nsv518641 CNV loss 19592680
nsv517196 CNV gain+loss 19592680
nsv457335 CNV loss 19166990
nsv1160328 CNV deletion 26073780
nsv1075908 CNV duplication 25765185
nsv1051692 CNV loss 25217958
esv27589 CNV loss 19812545
esv2422427 CNV duplication 17116639
dgv4856n54 CNV loss 21841781

Additional Variant Information for MIR3177 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3177

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3177 Gene

Disorders for MIR3177 Gene

Additional Disease Information for MIR3177

No disorders were found for MIR3177 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3177 Gene

Publications for MIR3177 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3177 Gene

Sources for MIR3177 Gene

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