microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3173 Gene

Data sources for MIR3173 Gene:

Subcategory (RNA class) for MIR3173 Gene

miRNA

Aliases for MIR3173 Gene

External Ids for MIR3173 Gene

Previous GeneCards Identifiers for MIR3173 Gene

  • GC14U901190
  • GC14M095604

Summaries for MIR3173 Gene

Entrez Gene Summary for MIR3173 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3173 Gene

MIR3173 (MicroRNA 3173) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3173 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3173 Gene

Genomics for MIR3173 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3173 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J095138 Promoter 0.8 EPDnew 250.7 +0.8 771 0.1 IKZF1 SPI1 ZNF366 ZNF473 MAX IKZF2 ZNF512 YBX1 NBN ETV6 MIR3173 DICER1 SNHG10 lnc-DICER1-2 HSALNG0103420 GSC
GH14J095137 Enhancer 0.5 ENCODE 250.7 +0.1 78 0.6 IKZF1 YBX1 ZNF512 ETV6 PRDM1 MIR3173 CLMN DICER1 lnc-DICER1-2 HSALNG0103420 GSC
GH14J095139 Promoter 0.3 EPDnew 250.7 +1.2 1165 0.1 MIR3173 DICER1 lnc-DICER1-2 HSALNG0103420 GSC
GH14J095155 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -18.9 -18915 3.8 ZSCAN16 CHD2 ZBTB10 SP1 FEZF1 NR2C1 MNT SMAD5 MBD2 ZNF217 DICER1 DICER1-AS1 lnc-DICER1-2 SCARNA13 SNHG10 MIR3173 GSC
GH14J095143 Promoter/Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -6.0 -5974 1.3 IRF2 IKZF1 SPI1 IKZF2 RELB MLLT1 DICER1 CLMN MIR3173 DICER1-AS1 lnc-DICER1-2 GSC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3173 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3173 Gene

Latest Assembly
chr14:95,137,919-95,137,986
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand

Previous Assembly
chr14:95,604,256-95,604,323
(GRCh37/hg19 by Entrez Gene)
Size:
68 bases
Orientation:
Minus strand

chr14:95,604,256-95,604,323
(GRCh37/hg19 by Ensembl)
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR3173 Gene

Genes around MIR3173 on UCSC Golden Path with GeneCards custom track
MIR3173 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3173 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3173 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3173 Gene

Proteins for MIR3173 Gene

Post-translational modifications for MIR3173 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3173 Gene

Domains & Families for MIR3173 Gene

Gene Families for MIR3173 Gene

HGNC:
genes like me logo Genes that share domains with MIR3173: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3173 Gene

Function for MIR3173 Gene

Phenotypes From GWAS Catalog for MIR3173 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3173 Gene

Localization for MIR3173 Gene

Gene Ontology (GO) - Cellular Components for MIR3173 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR3173: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3173 Gene

Pathways & Interactions for MIR3173 Gene

PathCards logo

SuperPathways for MIR3173 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3173 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3173 Gene

Drugs & Compounds for MIR3173 Gene

No Compound Related Data Available

Transcripts for MIR3173 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3173 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000017CCCB_9606 miRNA 22 5

RefSeq: NR_036131,

LncBase: hsa-miR-3173-3p,

miRBase: MIMAT0015048,

TarBase: hsa-miR-3173-3p,

ENA: FR772759.1:1..22:ncRNA, LM381666.1:1..22:ncRNA, LM611024.1:43..64:ncRNA,

URS000075C556_9606 precursor_RNA 68 4

RefSeq: NR_036131,

Ensembl: ENST00000580810 (view in UCSC) ,

miRBase: MI0014204,

ENA: LM611024.1:1..68:precursor_RNA,

URS00004216E6_9606 miRNA 22 4

RefSeq: NR_036131,

miRBase: MIMAT0019214,

TarBase: hsa-miR-3173-5p,

ENA: FR772760.1:1..22:ncRNA, LM382499.1:1..22:ncRNA, LM611024.1:5..26:ncRNA,

URS0000EFF36C_9606 precursor_RNA 62 1

MirGeneDB: Hsa-Mir-3173,

URS0000EFE1DA_9606 miRNA 23 1

MirGeneDB: Hsa-Mir-3173_5p,

MIR3173 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3173 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3173 Gene

No ASD Table

Relevant External Links for MIR3173 Gene

GeneLoc Exon Structure for
MIR3173

Expression for MIR3173 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3173 Gene

Orthologs for MIR3173 Gene

Evolution for MIR3173 Gene

ENSEMBL:
Gene Tree for MIR3173 (if available)
TreeFam:
Gene Tree for MIR3173 (if available)

No data available for Orthologs for MIR3173 Gene

Paralogs for MIR3173 Gene

No data available for Paralogs for MIR3173 Gene

Variants for MIR3173 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3173 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3173 Gene

Variant ID Type Subtype PubMed ID
esv3635396 CNV gain 21293372

Additional Variant Information for MIR3173 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3173

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3173 Gene

Disorders for MIR3173 Gene

Additional Disease Information for MIR3173

No disorders were found for MIR3173 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3173 Gene

Publications for MIR3173 Gene

  1. The downregulation of miR-3173 in B-cell acute lymphoblastic leukaemia promotes cell invasion via PTK2. (PMID: 29066351) Tian L … Tian X (Biochemical and biophysical research communications 2017) 3
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  3. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M … Kelso J (Genome biology and evolution 2012) 3
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  5. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3

Products for MIR3173 Gene

Sources for MIR3173 Gene