microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3168 Gene

Subcategory (RNA class) for MIR3168 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR3168 Gene

  • MicroRNA 3168 2 3 5
  • Hsa-Mir-3168 2 3
  • MIR3168 2 5
  • Hsa-MiR-3168 173
  • MIMAT0015043 50
  • MI0014199 50

External Ids for MIR3168 Gene

Previous GeneCards Identifiers for MIR3168 Gene

  • GC13U900768
  • GC13M041675

Summaries for MIR3168 Gene

Entrez Gene Summary for MIR3168 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3168 Gene

MIR3168 (MicroRNA 3168) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3168 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3168 Gene

Genomics for MIR3168 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3168 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J041107 Enhancer 0.6 ENCODE 0.4 -6.8 -6760 0.2 POLR2A TAF1 YY1 TFDP1 RFX5 TBP ZGPAT DRAP1 THAP11 ARID4B MIR3168 RN7SL597P RF00017-1400 lnc-WBP4-3 KBTBD6 lnc-KBTBD6-1 WBP4
GH13J041108 Enhancer 0.6 ENCODE 0.4 -6.6 -6586 0.1 YY1 TFDP1 RFX5 ZGPAT THAP11 ARID4B ZNF48 TAF1 POLR2A RBPJ MIR3168 RN7SL597P RF00017-1400 lnc-WBP4-3 KBTBD6 lnc-KBTBD6-1 WBP4
GH13J041098 Enhancer 0.2 Ensembl 0.7 +2.3 2299 0.8 RF00017-1399 MIR3168 KBTBD6 WBP4 lnc-KBTBD6-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3168 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3168 Gene

Genomic Locations for MIR3168 Gene
chr13:41,101,019-41,101,100
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand
chr13:41,675,155-41,675,236
(GRCh37/hg19)
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR3168 Gene

Genes around MIR3168 on UCSC Golden Path with GeneCards custom track
MIR3168 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3168 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3168 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3168 Gene

Proteins for MIR3168 Gene

Post-translational modifications for MIR3168 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3168 Gene

Domains & Families for MIR3168 Gene

Gene Families for MIR3168 Gene

HGNC:
genes like me logo Genes that share domains with MIR3168: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3168 Gene

Function for MIR3168 Gene

Phenotypes From GWAS Catalog for MIR3168 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3168 Gene

Localization for MIR3168 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3168 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3168 Gene

Pathways & Interactions for MIR3168 Gene

PathCards logo

SuperPathways for MIR3168 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3168 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3168 Gene

Drugs & Compounds for MIR3168 Gene

No Compound Related Data Available

Transcripts for MIR3168 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3168 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AFC1_9606 precursor_RNA 82 4

HGNC: 38249,

RefSeq: NR_036127,

Ensembl: ENST00000577639 (view in UCSC) ,

miRBase: MI0014199,

URS000020C393_9606 miRNA 17 3

RefSeq: NR_036127,

miRBase: MIMAT0015043,

TarBase: hsa-miR-3168,

MIR3168 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3168 Gene

No ASD Table

Relevant External Links for MIR3168 Gene

GeneLoc Exon Structure for
MIR3168

No data available for mRNA/cDNA for MIR3168 Gene

Expression for MIR3168 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3168 Gene

genes like me logo Genes that share expression patterns with MIR3168: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3168 Gene

Orthologs for MIR3168 Gene

Evolution for MIR3168 Gene

ENSEMBL:
Gene Tree for MIR3168 (if available)
TreeFam:
Gene Tree for MIR3168 (if available)

No data available for Orthologs for MIR3168 Gene

Paralogs for MIR3168 Gene

No data available for Paralogs for MIR3168 Gene

Variants for MIR3168 Gene

Additional dbSNP identifiers (rs#s) for MIR3168 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3168 Gene

Variant ID Type Subtype PubMed ID
nsv832587 CNV gain 17160897

Additional Variant Information for MIR3168 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3168

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3168 Gene

Disorders for MIR3168 Gene

No disorders were found for MIR3168 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3168 Gene

Publications for MIR3168 Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3168 Gene

Sources for MIR3168 Gene