microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3163 Gene

Data sources for MIR3163 Gene:

RNA type for MIR3163 Gene

miRNA

Aliases for MIR3163 Gene

External Ids for MIR3163 Gene

Previous GeneCards Identifiers for MIR3163 Gene

  • GC11U901739
  • GC11M066701

Summaries for MIR3163 Gene

Entrez Gene Summary for MIR3163 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3163 Gene

MIR3163 (MicroRNA 3163) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3163 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3163 Gene

Genomics for MIR3163 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3163 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J066933 Enhancer 1.2 Ensembl ENCODE dbSUPER 250.7 -1.0 -1037 4.8 NCOR1 IKZF1 ZNF592 CEBPA BRCA1 NFIC REST CEBPB BHLHE40 TBP MIR3163 RAD9A ACTN3 PC SYT12 LRFN4 RHOD DPP3-DT EIF1AD piR-44451-003
GH11J066929 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +5.0 4954 1.9 TRIM25 PRDM10 HDAC2 JUND NR2F6 GATA2 PHF21A KDM1A ATF3 FOS ACTN3 PC RHOD ZDHHC24 CDK2AP2 SPTBN2 MIR3163 piR-50437-082 LRFN4
GH11J066932 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.7 +2.1 2090 0.8 ZNF592 ELF1 ETV1 ZNF384 POLR2A ZBTB40 NR2C1 GABPB1 ATF7 POLR2B PC RHOD CTSF MIR3163 piR-50437-082 LRFN4
GH11J066938 Enhancer 0.5 Ensembl 0.7 -4.4 -4395 0.2 ZNF316 NFE2 MAFG MEIS2 CREB1 PKNOX1 ATF2 MEF2D EMSY SYT12 LRFN4 MIR3163 piR-44451-003 PC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3163 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3163 Gene

Latest Assembly
chr11:66,934,434-66,934,506
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand

Previous Assembly
chr11:66,701,905-66,701,977
(GRCh37/hg19 by Entrez Gene)
Size:
73 bases
Orientation:
Minus strand

chr11:66,701,905-66,701,977
(GRCh37/hg19 by Ensembl)
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR3163 Gene

Genes around MIR3163 on UCSC Golden Path with GeneCards custom track
MIR3163 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3163 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3163 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3163 Gene

Proteins for MIR3163 Gene

Post-translational modifications for MIR3163 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3163 Gene

Domains & Families for MIR3163 Gene

Gene Families for MIR3163 Gene

HGNC:
genes like me logo Genes that share domains with MIR3163: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3163 Gene

Function for MIR3163 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3163 Gene

Localization for MIR3163 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3163 Gene

Pathways & Interactions for MIR3163 Gene

PathCards logo

SuperPathways for MIR3163 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3163 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3163 Gene

Drugs & Compounds for MIR3163 Gene

No Compound Related Data Available

Transcripts for MIR3163 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3163 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075A0BF_9606 pre_miRNA 73 4

RefSeq: NR_036121,

Ensembl: ENST00000581592 (view in UCSC) ,

miRBase: MI0014193,

ENA: LM611018.1:1..73:precursor_RNA,

URS00003A5E54_9606 miRNA 22 3

RefSeq: NR_036121,

miRBase: MIMAT0015037,

ENA: LM381660.1:1..22:ncRNA, LM611018.1:10..31:ncRNA,

MIR3163 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3163 Gene

No ASD Table

Relevant External Links for MIR3163 Gene

GeneLoc Exon Structure for
MIR3163

No data available for mRNA/cDNA for MIR3163 Gene

Expression for MIR3163 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3163 Gene

Orthologs for MIR3163 Gene

Evolution for MIR3163 Gene

ENSEMBL:
Gene Tree for MIR3163 (if available)
TreeFam:
Gene Tree for MIR3163 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3163

No data available for Orthologs for MIR3163 Gene

Paralogs for MIR3163 Gene

No data available for Paralogs for MIR3163 Gene

Variants for MIR3163 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3163 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3163 Gene

Variant ID Type Subtype PubMed ID
nsv555226 CNV gain 21841781
nsv832194 CNV gain+loss 17160897

Additional Variant Information for MIR3163 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3163
Leiden Open Variation Database (LOVD)
MIR3163

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3163 Gene

Disorders for MIR3163 Gene

Additional Disease Information for MIR3163

No disorders were found for MIR3163 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3163 Gene

Publications for MIR3163 Gene

  1. MicroRNA-3163 targets ADAM-17 and enhances the sensitivity of hepatocellular carcinoma cells to molecular targeted agents. (PMID: 31611551) Yang B … Lu Y (Cell death & disease 2019) 3
  2. Skp2 regulates non-small cell lung cancer cell growth by Meg3 and miR-3163. (PMID: 26482610) Su L … Huo X (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3163 Gene

Sources for MIR3163 Gene