microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3159 Gene

Data sources for MIR3159 Gene:

Subcategory (RNA class) for MIR3159 Gene

miRNA

Aliases for MIR3159 Gene

External Ids for MIR3159 Gene

Previous GeneCards Identifiers for MIR3159 Gene

  • GC11U901538
  • GC09P037795
  • GC09P037796
  • GC09P037797
  • GC09P037799
  • GC09P037801
  • GC09P037802
  • GC11P018411

Summaries for MIR3159 Gene

Entrez Gene Summary for MIR3159 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3159 Gene

MIR3159 (MicroRNA 3159) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3159 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3159 Gene

Genomics for MIR3159 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3159 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J018385 Enhancer 0.2 dbSUPER 250.7 -0.9 -910 1.8 MIR3159 LDHC HSALNG0082999 LDHA HPS5
GH11J018382 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -3.7 -3713 3 BCL11A CEBPA DEK IRF2 ELF1 CEBPB ZNF395 GTF2E2 FOXA2 SMAD4 HSALNG0082999 LDHC LDHA LDHAL6A SPTY2D1 HPS5 TSG101 MIR3159
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3159 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3159 Gene

Latest Assembly
chr11:18,387,787-18,387,860
(GRCh38/hg38)
Size:
74 bases
Orientation:
Plus strand

Previous Assembly
chr11:18,409,334-18,409,407
(GRCh37/hg19 by Entrez Gene)
Size:
74 bases
Orientation:
Plus strand

chr11:18,409,334-18,409,407
(GRCh37/hg19 by Ensembl)
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR3159 Gene

Genes around MIR3159 on UCSC Golden Path with GeneCards custom track
MIR3159 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3159 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3159 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3159 Gene

Proteins for MIR3159 Gene

Post-translational modifications for MIR3159 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3159 Gene

Domains & Families for MIR3159 Gene

Gene Families for MIR3159 Gene

HGNC:
genes like me logo Genes that share domains with MIR3159: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3159 Gene

Function for MIR3159 Gene

Phenotypes From GWAS Catalog for MIR3159 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3159 Gene

Localization for MIR3159 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3159 Gene

Pathways & Interactions for MIR3159 Gene

PathCards logo

SuperPathways for MIR3159 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3159 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3159 Gene

Drugs & Compounds for MIR3159 Gene

No Compound Related Data Available

Transcripts for MIR3159 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3159 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C9AA_9606 precursor_RNA 74 4

RefSeq: NR_036116,

Ensembl: ENST00000584572 (view in UCSC) ,

miRBase: MI0014188,

ENA: LM611013.1:1..74:precursor_RNA,

URS00002FB065_9606 miRNA 22 4

RefSeq: NR_036116,

miRBase: MIMAT0015033,

TarBase: hsa-miR-3159,

ENA: LM381656.1:1..22:ncRNA, LM611013.1:10..31:ncRNA,

MIR3159 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3159 Gene

No ASD Table

Relevant External Links for MIR3159 Gene

GeneLoc Exon Structure for
MIR3159

No data available for mRNA/cDNA for MIR3159 Gene

Expression for MIR3159 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3159 Gene

Orthologs for MIR3159 Gene

Evolution for MIR3159 Gene

ENSEMBL:
Gene Tree for MIR3159 (if available)
TreeFam:
Gene Tree for MIR3159 (if available)

No data available for Orthologs for MIR3159 Gene

Paralogs for MIR3159 Gene

No data available for Paralogs for MIR3159 Gene

Variants for MIR3159 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3159 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3159 Gene

Variant ID Type Subtype PubMed ID
nsv509392 CNV insertion 20534489
nsv510999 OTHER complex 20534489
nsv553633 CNV gain 21841781

Additional Variant Information for MIR3159 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3159

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3159 Gene

Disorders for MIR3159 Gene

Additional Disease Information for MIR3159

No disorders were found for MIR3159 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3159 Gene

Publications for MIR3159 Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3159 Gene

Sources for MIR3159 Gene