microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3158-2 Gene

Subcategory (RNA class) for MIR3158-2 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR3158-2 Gene

  • MicroRNA 3158-2 2 3 5
  • Hsa-MiR-3158-3p 166 177
  • Hsa-Mir-3158-2 3
  • MIMAT0015032 51
  • MIMAT0019211 51
  • Mir-3158-2 3
  • MIR3158-2 2
  • MI0014187 51

External Ids for MIR3158-2 Gene

Previous GeneCards Identifiers for MIR3158-2 Gene

  • GC10U901427
  • GC10M103363

Summaries for MIR3158-2 Gene

Entrez Gene Summary for MIR3158-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3158-2 Gene

MIR3158-2 (MicroRNA 3158-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3158-2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3158-2 Gene

Genomics for MIR3158-2 Gene

GeneHancer (GH) Regulatory Elements for MIR3158-2 Gene

Promoters and enhancers for MIR3158-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J101602 Enhancer 0.8 ENCODE 500.7 -1.4 -1412 0.2 CTCF NRF1 GABPA REST MYC RAD21 CTBP1 TRIM22 SMC3 MXI1 MIR3158-1 MIR3158-2 lnc-POLL-1 DPCD
GH10J101601 Enhancer 0.4 Ensembl 500.7 +0.1 96 0.4 ATF2 ZFP69B SP7 ESR1 ZFX MIR3158-1 MIR3158-2 POLL lnc-BTRC-4 DPCD
GH10J101606 Enhancer 0.8 Ensembl ENCODE 0.4 -5.8 -5846 1.3 CTBP1 KLF13 ZFHX2 TAL1 NR2F1 HDAC2 KLF17 TCF12 NR2F6 MTA2 POLL DPCD MIR3158-2 lnc-POLL-1
GH10J101610 Enhancer 0.6 Ensembl ENCODE 0.4 -10.3 -10317 1.7 POLR2A GABPB1 MAX lnc-POLL-1 MIR3158-2 FBXW4
GH10J101608 Enhancer 0.4 Ensembl 0.4 -7.8 -7804 1.8 POLR2A FOS SPI1 FGF8 NPM3 HPS6 POLL lnc-POLL-1 MIR3158-2 DPCD
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3158-2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3158-2 Gene

Genomic Locations for MIR3158-2 Gene
chr10:101,601,417-101,601,497
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr10:103,361,174-103,361,254
(GRCh37/hg19)
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR3158-2 Gene

Genes around MIR3158-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3158-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3158-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3158-2 Gene

Proteins for MIR3158-2 Gene

Post-translational modifications for MIR3158-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3158-2 Gene

Domains & Families for MIR3158-2 Gene

Gene Families for MIR3158-2 Gene

HGNC:
genes like me logo Genes that share domains with MIR3158-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3158-2 Gene

Function for MIR3158-2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3158-2 Gene

Localization for MIR3158-2 Gene

Gene Ontology (GO) - Cellular Components for MIR3158-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR3158-2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3158-2 Gene

Pathways & Interactions for MIR3158-2 Gene

PathCards logo

SuperPathways for MIR3158-2 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR3158-2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3158-2 Gene

Drugs & Compounds for MIR3158-2 Gene

No Compound Related Data Available

Transcripts for MIR3158-2 Gene

mRNA/cDNA for MIR3158-2 Gene

3 RNACentral transcripts :
2 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
8 ENA transcripts :
1 LncBase transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3158-2 Gene

No ASD Table

Relevant External Links for MIR3158-2 Gene

GeneLoc Exon Structure for
MIR3158-2

Expression for MIR3158-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3158-2 Gene

genes like me logo Genes that share expression patterns with MIR3158-2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3158-2 Gene

Orthologs for MIR3158-2 Gene

Evolution for MIR3158-2 Gene

ENSEMBL:
Gene Tree for MIR3158-2 (if available)
TreeFam:
Gene Tree for MIR3158-2 (if available)

No data available for Orthologs for MIR3158-2 Gene

Paralogs for MIR3158-2 Gene

No data available for Paralogs for MIR3158-2 Gene

Variants for MIR3158-2 Gene

Additional dbSNP identifiers (rs#s) for MIR3158-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3158-2 Gene

Variant ID Type Subtype PubMed ID
esv2750847 CNV gain 17911159
esv3624382 CNV gain 21293372
nsv1053934 CNV gain 25217958
nsv527185 CNV loss 19592680

Additional Variant Information for MIR3158-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3158-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3158-2 Gene

Disorders for MIR3158-2 Gene

Additional Disease Information for MIR3158-2

No disorders were found for MIR3158-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3158-2 Gene

Publications for MIR3158-2 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 54
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 54
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 54
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR3158-2 Gene

Sources for MIR3158-2 Gene